The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling

Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes

(2016) Gina A. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer

(2015) L. S. Schneider et al.   CANCER RESEARCH

Mammary gland development: cell fate specification, stem cells and the microenvironment

(2015) J. L. Inman et al.   DEVELOPMENT

Latent transforming growth factor binding protein 4 regulates transforming growth factor beta receptor stability

(2015) C.-T. Su et al.   HUMAN MOLECULAR GENETICS

Inhibition of vacuolar ATPase subunit in tumor cells delays tumor growth by decreasing the essential macrophage population in the tumor microenvironment

(2015) G K Katara et al.   ONCOGENE

TGF-β1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis

(2015) M-F Pang et al.   ONCOGENE

Recent Insights into the Structure, Regulation, and Function of the V-ATPases

(2015) Kristina Cotter et al.   TRENDS IN BIOCHEMICAL SCIENCES

Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer

(2015) Arpita Kulshrestha et al.   Oncotarget

Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor

(2015) Varkha Agrawal et al.   Scientific Reports

Notch Signaling in Inflammation-Induced Preterm Labor

(2015) Mukesh K. Jaiswal et al.   Scientific Reports

Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation

(2015) Maria Merkulova et al.   Scientific Reports

Autophagy eliminates cytoplasmic β-catenin and NICD to promote the cardiac differentiation of P19CL6 cells

(2014) Zhuqing Jia et al.   CELLULAR SIGNALLING

Molecular Pathways: Translational and Therapeutic Implications of the Notch Signaling Pathway in Cancer

(2014) R. A. Previs et al.   CLINICAL CANCER RESEARCH

Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells

(2014) R. J. Huebner et al.   DEVELOPMENT

Conditional Overexpression of Liver Receptor Homolog-1 in Female Mouse Mammary Epithelium Results in Altered Mammary Morphogenesis via the Induction of TGF-β

(2014) Kyren A. Lazarus et al.   ENDOCRINOLOGY

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

(2014) Timothy J. Sargeant et al.   NATURE CELL BIOLOGY

How to Take Autophagy and Endocytosis Up a Notch

(2014) Julia M. I. Barth et al.   Biomed Research International

V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activationin vivo

(2013) Rebekka Kubisch et al.   INTERNATIONAL JOURNAL OF CANCER

Notch3 marks clonogenic mammary luminal progenitor cells in vivo

(2013) Daniel Lafkas et al.   JOURNAL OF CELL BIOLOGY

Regulation of Luminal Acidification by the V-ATPase

(2013) Sylvie Breton et al.   PHYSIOLOGY

Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytes

(2013) Mallika Valapala et al.   Nature Communications

The lack of autophagy triggers precocious activation of Notch signaling during Drosophila oogenesis

(2012) Julia MI Barth et al.   BMC DEVELOPMENTAL BIOLOGY

Endocytosis and control of Notch signaling

(2012) Vasundhara Kandachar et al.   CURRENT OPINION IN CELL BIOLOGY

Further characterization of ATP6V0A2-related autosomal recessive cutis laxa

(2012) Björn Fischer et al.   HUMAN GENETICS

Postpartum Remodeling, Lactation, and Breast Cancer Risk: Summary of a National Cancer Institute–Sponsored Workshop

(2012) Jessica M. Faupel-Badger et al.   JNCI-Journal of the National Cancer Institute

Endocytic routes to Notch activation

(2012) Martin Baron   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Elf5 Regulates Mammary Gland Stem/Progenitor Cell Fate by Influencing Notch Signaling

(2012) Rumela Chakrabarti et al.   STEM CELLS

Modulation of mammary gland development in pre-pubertal mice as affected by soya and milk protein supplements

(2011) Brenda Alston-Mills et al.   BRITISH JOURNAL OF NUTRITION

From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer

(2011) Benjamin Tiede et al.   CELL RESEARCH

Necrotic cell death: harnessing the Dark side of the Force in mammary gland involution

(2011) Cliff J. Luke et al.   NATURE CELL BIOLOGY

Regulation and Isoform Function of the V-ATPases

(2010) Masashi Toei et al.   BIOCHEMISTRY

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

(2010) Ö Yalcin-Ozuysal et al.   CELL DEATH AND DIFFERENTIATION

Endocytic Internalization Routes Required for Delta/Notch Signaling

(2010) Sarah L. Windler et al.   CURRENT BIOLOGY

The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor

(2010) T. Vaccari et al.   DEVELOPMENT

The Pathophysiology of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β in Normal and Malignant Mammary Epithelial Cells

(2010) Molly A. Taylor et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development

(2010) Ahmet Ucar et al.   NATURE GENETICS

Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells

(2010) M. Mazzone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-  Biology in Mammary Development and Breast Cancer

(2010) H. Moses et al.   Cold Spring Harbor Perspectives in Biology

Function of a Subunit Isoforms of the V-ATPase in pH Homeostasis andin VitroInvasion of MDA-MB231 Human Breast Cancer Cells

(2009) Ayana Hinton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Cathepsins in Involution and Breast Cancer

(2009) Christine J. Watson et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment

(2008) Toula Bouras et al.   Cell Stem Cell

Mammary development in the embryo and adult: a journey of morphogenesis and commitment

(2008) C. J. Watson et al.   DEVELOPMENT

Endocytosis: A Positive or a Negative Influence on Wnt Signalling?

(2007) Maria Gagliardi et al.   TRAFFIC