Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation

Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?

(2017) Ambra Vestri et al.   Frontiers in Pharmacology

Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment

(2016) F. Pierucci et al.   ARCHIVES OF TOXICOLOGY

Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases

(2016) Antoine Monsel et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2

(2016) Alena Chumanevich et al.   MEDIATORS OF INFLAMMATION

Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro-engineering of their niche

(2016) Julianna Kobolak et al.   METHODS

MicroRNA-195a-3pinhibits angiogenesis by targetingMmp2in murine mesenchymal stem cells

(2016) Fan Gao et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

The ever-expanding role of HIF in tumour and stromal biology

(2016) Edward L. LaGory et al.   NATURE CELL BIOLOGY

Effects of matrix metalloproteinases on the fate of mesenchymal stem cells

(2016) Sami G. Almalki et al.   Stem Cell Research & Therapy

Hypoxia Inducible Factor-1αRegulates the Migration of Bone Marrow Mesenchymal Stem Cells via Integrinα4

(2016) Jong Ho Choi et al.   Stem Cells International

Composite microsphere-functionalized scaffold for the controlled release of small molecules in tissue engineering

(2016) Laura Pandolfi et al.   Journal of Tissue Engineering

The Regulation of Cellular Responses to Mechanical Cues by Rho GTPases

(2016) Jing Hoon et al.   Cells

Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?

(2016) Ann De Becker et al.   World Journal of Stem Cells

Human bone marrow stem cells cultured under hypoxic conditions present altered characteristics and enhanced in vivo tissue regeneration

(2015) Jung-Seok Lee et al.   BONE

The effect of the bioactive sphingolipids S1P and C1P on multipotent stromal cells – new opportunities in regenerative medicine

(2015) Krzysztof Marycz et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Mesenchymal Stem Cells as a Biological Drug for Heart Disease

(2015) Cristina Sanina et al.   CIRCULATION RESEARCH

Paracrine action of mesenchymal stromal cells delivered by microspheres contributes to cutaneous wound healing and prevents scar formation in mice

(2015) Sha Huang et al.   CYTOTHERAPY

BMSCs and hematopoiesis

(2015) Andrés García-García et al.   IMMUNOLOGY LETTERS

Cortactin promotes colon cancer progression by regulating ERK pathway

(2015) QING-FENG NI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

(2015) Richard L. Proia et al.   JOURNAL OF CLINICAL INVESTIGATION

MMP2 and MMP9 participate in S1P-induced invasion of follicular ML-1 thyroid cancer cells

(2015) Veronica Kalhori et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process

(2015) John H. Henson et al.   MOLECULAR BIOLOGY OF THE CELL

Role of Sphingosine Kinase/S1P Axis in ECM Remodeling of Cardiac Cells Elicited by Relaxin

(2015) Alessia Frati et al.   MOLECULAR ENDOCRINOLOGY

Mesenchymal stem cells-based therapy as a potential treatment in neurodegenerative disorders: is the escape from senescence an answer?

(2015) Alessandro Castorina et al.   Neural Regeneration Research

Improved Proliferation and Differentiation of Bone Marrow Mesenchymal Stem Cells Into Vascular Endothelial Cells With Sphingosine 1-Phosphate

(2015) W. Lu et al.   TRANSPLANTATION PROCEEDINGS

MSCs seeded on bioengineered scaffolds improve skin wound healing in rats

(2015) Lucia Formigli et al.   WOUND REPAIR AND REGENERATION

Altered protein secretions during interactions between adipose tissue- or bone marrow-derived stromal cells and inflammatory cells

(2015) Hidemi Hattori et al.   Stem Cell Research & Therapy

Amniotic Mesenchymal Stem Cells Can Enhance Angiogenic Capacity via MMPsIn VitroandIn Vivo

(2015) Fei Jiang et al.   Biomed Research International

Adult Mesenchymal Stem Cells: When, Where, and How

(2015) Arnold I. Caplan   Stem Cells International

Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells

(2014) Chiara Sassoli et al.   EXPERIMENTAL CELL RESEARCH

Sphingosine-1-phosphate/S1P Receptors Signaling Modulates Cell Migration in Human Bone Marrow-Derived Mesenchymal Stem Cells

(2014) Yaxian Kong et al.   MEDIATORS OF INFLAMMATION

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

Mesenchymal Stromal Cell Secreted Sphingosine 1-Phosphate (S1P) Exerts a Stimulatory Effect on Skeletal Myoblast Proliferation

(2014) Chiara Sassoli et al.   PLoS One

Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-αStimulated Protein/Gene 6

(2014) Zhigang He et al.   Stem Cells International

Activation of intracellular matrix metalloproteinase-2 by reactive oxygen–nitrogen species: Consequences and therapeutic strategies in the heart

(2013) Anna L. Jacob-Ferreira et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Sphingosine 1-phosphate signalling

(2013) K. Mendelson et al.   DEVELOPMENT

Sphingosine 1-Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Mesenchymal Cell Migration through S1P Activation of Complementary Kinase Pathways

(2013) Patrick Quint et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine-1-Phosphate as a Regulator of Hypoxia-Induced Factor-1α in Thyroid Follicular Carcinoma Cells

(2013) Veronica Kalhori et al.   PLoS One

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

(2013) D. M. Gilkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Nontranscriptional Role for HIF-1  as a Direct Inhibitor of DNA Replication

(2013) M. E. Hubbi et al.   Science Signaling

In situ mechanotransduction via vinculin regulates stem cell differentiation

(2013) Andrew W. Holle et al.   STEM CELLS

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

(2013) Bryan N. Brown et al.   Translational Research

Matrix Mechanics and Fluid Shear Stress Control Stem Cells Fate in Three Dimensional Microenvironment

(2013) Guobao Chen et al.   Current Stem Cell Research & Therapy

Bone Marrow-Derived Mesenchymal Stem Cells Differentiate to Hepatic Myofibroblasts by Transforming Growth Factor-β1 via Sphingosine Kinase/Sphingosine 1-Phosphate (S1P)/S1P Receptor Axis

(2012) Le Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Bone Marrow Mesenchymal Stromal Cells Stimulate Skeletal Myoblast Proliferation through the Paracrine Release of VEGF

(2012) Chiara Sassoli et al.   PLoS One

Trophic Actions of Bone Marrow-Derived Mesenchymal Stromal Cells for Muscle Repair/Regeneration

(2012) Chiara Sassoli et al.   Cells

The Secretory Profiles of Cultured Human Articular Chondrocytes and Mesenchymal Stem Cells: Implications for Autologous Cell Transplantation Strategies

(2011) Martin Polacek et al.   CELL TRANSPLANTATION

Cortactin Controls Cell Motility and Lamellipodial Dynamics by Regulating ECM Secretion

(2011) Bong Hwan Sung et al.   CURRENT BIOLOGY

Mesenchymal stem cells and their microenvironment

(2011) Ingrid et al.   Frontiers in Bioscience-Landmark

Mesenchymal stromal cells affect cardiomyocyte growth through juxtacrine Notch-1/Jagged-1 signaling and paracrine mechanisms: Clues for cardiac regeneration

(2011) Chiara Sassoli et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Dermal matrix scaffold engineered with adult mesenchymal stem cells and platelet-rich plasma as a potential tool for tissue repair and regeneration

(2011) Lucia Formigli et al.   Journal of Tissue Engineering and Regenerative Medicine

Cortactin

(2011) Kellye C. Kirkbride et al.   Cell Adhesion & Migration

Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

(2010) Jerold Chun et al.   CLINICAL NEUROPHARMACOLOGY

Paracrine mechanisms of stem cell reparative and regenerative actions in the heart

(2010) Maria Mirotsou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

An update on sphingosine-1-phosphate and other sphingolipid mediators

(2010) Henrik Fyrst et al.   Nature Chemical Biology

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

In vitro study of matrix metalloproteinase/tissue inhibitor of metalloproteinase production by mesenchymal stromal cells in response to inflammatory cytokines: the role of their migration in injured tissues

(2009) Tatiana Tondreau et al.   CYTOTHERAPY

Cortactin Promotes Migration and Platelet-derived Growth Factor-induced Actin Reorganization by Signaling to Rho-GTPases

(2009) Frank P.L. Lai et al.   MOLECULAR BIOLOGY OF THE CELL

Cdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activation

(2008) Eric Ispanovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sphingosine Kinase as an Oncogene: Autocrine Sphingosine 1-Phoshate Modulates ML-1 Thyroid Carcinoma Cell Migration by a Mechanism Dependent on Protein Kinase C-α and ERK1/2

(2008) N. Bergelin et al.   ENDOCRINOLOGY

S1P induced changes in epithelial ovarian cancer proteolysis, invasion, and attachment are mediated by Gi and Rac

(2008) Kathleen M. Devine et al.   GYNECOLOGIC ONCOLOGY