In situ mechanotransduction via vinculin regulates stem cell differentiation

The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices

(2012) Yu Suk Choi et al.   BIOMATERIALS

Coordination of Satellite Cell Activation and Self-Renewal by Par-Complex-Dependent Asymmetric Activation of p38α/β MAPK

(2012) Andrew Troy et al.   Cell Stem Cell

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

Small Molecule Inhibition of RISC Loading

(2011) Grace S. Tan et al.   ACS Chemical Biology

Head/tail interaction of vinculin influences cell mechanical behavior

(2011) Gerold Diez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanical derivation of functional myotubes from adipose-derived stem cells

(2011) Yu Suk Choi et al.   BIOMATERIALS

More than a feeling: discovering, understanding, and influencing mechanosensing pathways

(2011) Andrew W Holle et al.   CURRENT OPINION IN BIOTECHNOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

(2011) Masha Prager-Khoutorsky et al.   NATURE CELL BIOLOGY

Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

(2011) Justin R. Tse et al.   PLoS One

Vinculin Facilitates Cell Invasion into Three-dimensional Collagen Matrices

(2010) Claudia T. Mierke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Optimal matrix rigidity for stress-fibre polarization in stem cells

(2010) A. Zemel et al.   Nature Physics

Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix

(2009) Farshid Guilak et al.   Cell Stem Cell

Matrix Strains Induced by Cells: Computing How Far Cells Can Feel

(2009) Shamik Sen et al.   Cellular and Molecular Bioengineering

Novel Nuclear Nesprin-2 Variants Tether Active Extracellular Signal-regulated MAPK1 and MAPK2 at Promyelocytic Leukemia Protein Nuclear Bodies and Act to Regulate Smooth Muscle Cell Proliferation

(2009) Derek T. Warren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation

(2008) Andrew S. Rowlands et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Mechanical Environment of Bone Marrow: A Review

(2008) Umut Atakan Gurkan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Combinatorial Signaling Microenvironments for Studying Stem Cell Fate

(2008) Christopher J. Flaim et al.   STEM CELLS AND DEVELOPMENT

Mechano-Coupling and Regulation of Contractility by the Vinculin Tail Domain

(2007) Claudia Tanja Mierke et al.   BIOPHYSICAL JOURNAL

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL