Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-αStimulated Protein/Gene 6

Modification of Hyaluronan by Heavy Chains of Inter-α-Inhibitor in Idiopathic Pulmonary Arterial Hypertension

(2014) Mark E. Lauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mesenchymal stem cells transplantation suppresses inflammatory responses in global cerebral ischemia: contribution of TNF-α-induced protein 6

(2013) Qing-ming Lin et al.   ACTA PHARMACOLOGICA SINICA

Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungs

(2013) Andrea M. Foskett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Paracrine Mechanisms of Mesenchymal Stem Cell-Based Therapy: Current Status and Perspectives

(2013) Xiaoting Liang et al.   CELL TRANSPLANTATION

TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity

(2013) D. J. Kota et al.   DIABETES

TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds

(2013) Yu Qi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Administration of TSG-6 improves memory after traumatic brain injury in mice

(2013) Jun Watanabe et al.   NEUROBIOLOGY OF DISEASE

TSG-6 Protein Is Crucial for the Development of Pulmonary Hyaluronan Deposition, Eosinophilia, and Airway Hyperresponsiveness in a Murine Model of Asthma

(2012) Shadi Swaidani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intravenous Mesenchymal Stem Cells Prevented Rejection of Allogeneic Corneal Transplants by Aborting the Early Inflammatory Response

(2012) Joo Youn Oh et al.   MOLECULAR THERAPY

Role of mesenchymal stem cell therapy in Crohn’s disease

(2012) Jignesh Dalal et al.   PEDIATRIC RESEARCH

Mesenchymal Stem Cells Attenuate Peritoneal Injury through Secretion of TSG-6

(2012) Nan Wang et al.   PLoS One

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

(2011) Darwin J Prockop et al.   MOLECULAR THERAPY

The immunomodulatory properties of mesenchymal stem cells

(2011) Ilaria Marigo et al.   Seminars in Immunopathology

Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

(2011) Gavin W. Roddy et al.   STEM CELLS

Comparative Analysis of Paracrine Factor Expression in Human Adult Mesenchymal Stem Cells Derived from Bone Marrow, Adipose, and Dermal Tissue

(2011) Sarah Tzu-Feng Hsiao et al.   STEM CELLS AND DEVELOPMENT

Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6

(2011) Svitlana Danchuk et al.   Stem Cell Research & Therapy

Therapeutic Potential of Mesenchymal Stem Cells for Severe Acute Lung Injury

(2010) Michael A. Matthay et al.   CHEST

Bone marrow-derived mesenchymal stem cells for treatment of heart failure: is it all paracrine actions and immunomodulation?

(2010) Pankaj Kumar Mishra   Journal of Cardiovascular Medicine

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs

(2010) Federica Collino et al.   PLoS One

Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury

(2010) J. Y. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal stem cell therapy: Two steps forward, one step back

(2010) James Ankrum et al.   TRENDS IN MOLECULAR MEDICINE

Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease

(2009) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Sleuthing the Source of Regeneration by MSCs

(2009) Mark Pittenger   Cell Stem Cell

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

DAMPs and inflammatory processes: the role of redox in the different outcomes

(2009) Sonia Carta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury

(2009) S. Bruno et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

(2009) Tian Sheng Chen et al.   NUCLEIC ACIDS RESEARCH

Stem cell paracrine actions and tissue regeneration

(2009) Priya R Baraniak et al.   Regenerative Medicine

Mesenchymal stem cells enhance the viability and proliferation of human fetal intestinal epithelial cells following hypoxic injury via paracrine mechanisms

(2009) Brent R. Weil et al.   SURGERY

Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy

(2008) Massimiliano Gnecchi et al.   CIRCULATION RESEARCH

IGF-1–Overexpressing Mesenchymal Stem Cells Accelerate Bone Marrow Stem Cell Mobilization via Paracrine Activation of SDF-1α/CXCR4 Signaling to Promote Myocardial Repair

(2008) Husnain Kh Haider et al.   CIRCULATION RESEARCH

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool

(2008) J. García-Castro et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Acute myocardial infarction

(2008) Harvey D White et al.   LANCET

Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing

(2008) Liwen Chen et al.   PLoS One