Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome

Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles

(2017) Stella Cosenza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis

(2017) Taeko Shigemoto-Kuroda et al.   Stem Cell Reports

Immunomodulatory Properties of Induced Pluripotent Stem Cell-Derived Mesenchymal Cells

(2016) Jia Ng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Treatment of primary Sjögren syndrome

(2016) Alain Saraux et al.   Nature Reviews Rheumatology

Interleukin-15 as a potential new target in Sjögren's syndrome-associated inflammation

(2016) Margherita Sisto et al.   PATHOLOGY

Autoimmune manifestations in aged mice arise from early-life immune dysregulation

(2016) T. I. Mahmoud et al.   Science Translational Medicine

Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs

(2016) Catherine E. Hughes et al.   Frontiers in Immunology

Sjögren syndrome

(2016) Pilar Brito-Zerón et al.   Nature Reviews Disease Primers

Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions

(2016) Mariano Di Trapani et al.   Scientific Reports

Human mesenchymal stem cells and derived extracellular vesicles induce regulatory dendritic cells in type 1 diabetic patients

(2015) Enrica Favaro et al.   DIABETOLOGIA

The secretome of mesenchymal stromal cells: Role of extracellular vesicles in immunomodulation

(2015) Stefania Bruno et al.   IMMUNOLOGY LETTERS

The clinical spectrum of autoimmune congenital heart block

(2015) Pilar Brito-Zerón et al.   Nature Reviews Rheumatology

Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye

(2015) Jung Hwa Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI

(2015) Dong-ki Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of Sjögren's Syndrome Years Before Diagnosis and Identification of Patients With Early Onset and Severe Disease Course by Autoantibody Profiling

(2015) Elke Theander et al.   Arthritis & Rheumatology

Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway

(2014) N. C. Kyriakidis et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome

(2014) Ya-Zhuo Gong et al.   JOURNAL OF AUTOIMMUNITY

Identification of IL-18 and Th17 Cells in Salivary Glands of Patients with Sjogren's Syndrome, and Amplification of IL-17-Mediated Secretion of Inflammatory Cytokines from Salivary Gland Cells by IL-18

(2014) A. Sakai et al.   JOURNAL OF IMMUNOLOGY

The Histopathology of Labial Salivary Glands in Primary Sjögren’s Syndrome: Focusing on Follicular Helper T Cells in the Inflammatory Infiltrates

(2014) Krisztina Szabo et al.   MEDIATORS OF INFLAMMATION

Quantitative Analysis of Protein and Gene Expression in Salivary Glands of Sjogren’s-Like Disease NOD Mice Treated by Bone Marrow Soup

(2014) Kaori Misuno et al.   PLoS One

TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo

(2014) Ryang Hwa Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs

(2014) Qingguo Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Umbilical cord mesenchymal stem cells inhibit the differentiation of circulating T follicular helper cells in patients with primary Sjögren’s syndrome through the secretion of indoleamine 2,3-dioxygenase

(2014) Rui Liu et al.   RHEUMATOLOGY

Transient Activation of Hedgehog Pathway Rescued Irradiation-Induced Hyposalivation by Preserving Salivary Stem/Progenitor Cells and Parasympathetic Innervation

(2013) B. Hai et al.   CLINICAL CANCER RESEARCH

Autoantibodies Present Before Symptom Onset in Primary Sjögren Syndrome

(2013) Roland Jonsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Advances in understanding the pathogenesis of primary Sjögren's syndrome

(2013) Gaëtane Nocturne et al.   Nature Reviews Rheumatology

Innate Immune Signaling Induces Interleukin-7 Production from Salivary Gland Cells and Accelerates the Development of Primary Sjӧgren’s Syndrome in a Mouse Model

(2013) Jun-O Jin et al.   PLoS One

Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome

(2012) J. Xu et al.   BLOOD

Preactivation of Human MSCs with TNF-α Enhances Tumor-Suppressive Activity

(2012) Ryang Hwa Lee et al.   Cell Stem Cell

Mesenchymal Stromal Cells Improve Salivary Function and Reduce Lymphocytic Infiltrates in Mice with Sjögren's-Like Disease

(2012) Saeed Khalili et al.   PLoS One

Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome

(2011) Keiko Yoshimoto et al.   ARTHRITIS RESEARCH & THERAPY

IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection

(2010) D. G. Brooks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

(2010) T. J. Bartosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome

(2009) Maria I. Christodoulou et al.   JOURNAL OF AUTOIMMUNITY

Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression

(2009) Guangwen Ren et al.   STEM CELLS