Innate Immune Signaling Induces Interleukin-7 Production from Salivary Gland Cells and Accelerates the Development of Primary Sjӧgren’s Syndrome in a Mouse Model

Systemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung

(2012) J.-O. Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anti-IL-7 receptor-  reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function

(2012) L.-F. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

(2011) Marc Pellegrini et al.   CELL

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

CXCR3 ligands: redundant, collaborative and antagonistic functions

(2011) Joanna R Groom et al.   IMMUNOLOGY AND CELL BIOLOGY

Upregulated IL-7 Receptor   Expression on Colitogenic Memory CD4+ T Cells May Participate in the Development and Persistence of Chronic Colitis

(2011) T. Shinohara et al.   JOURNAL OF IMMUNOLOGY

Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells

(2011) Jonathan Sprent et al.   NATURE IMMUNOLOGY

Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren’s syndrome-like disease

(2011) S-R Nandula et al.   ORAL DISEASES

Location of Immunization and Interferon-γ Are Central to Induction of Salivary Gland Dysfunction in Ro60 Peptide Immunized Model of Sjögren's Syndrome

(2011) Hongen Yin et al.   PLoS One

Systemic Autoimmunity and Lymphoproliferation Are Associated with Excess IL-7 and Inhibited by IL-7Rα Blockade

(2011) Rosana Gonzalez-Quintial et al.   PLoS One

Antiviral responses induced by the TLR3 pathway

(2011) Misako Matsumoto et al.   REVIEWS IN MEDICAL VIROLOGY

MDA5 and TLR3 Initiate Pro-Inflammatory Signaling Pathways Leading to Rhinovirus-Induced Airways Inflammation and Hyperresponsiveness

(2011) Qiong Wang et al.   PLoS Pathogens

Cytokines in Sjogren's syndrome: potential therapeutic targets

(2010) N. Roescher et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjögren's syndrome correlates with increased inflammation

(2010) A. Bikker et al.   ARTHRITIS AND RHEUMATISM

Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators

(2010) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Pathogenesis of Sjögrenʼs syndrome and therapeutic consequences

(2010) Xavier Mariette et al.   CURRENT OPINION IN RHEUMATOLOGY

Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function

(2010) Umesh S. Deshmukh et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Toll-like Receptor3-mediated Induction of Chemokines in Salivary Epithelial Cells

(2010) Jingchao Li et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

Pathogenetic mechanisms in the initiation and perpetuation of Sjögren's syndrome

(2010) Michael Voulgarelis et al.   Nature Reviews Rheumatology

Sjögren’s syndrome: An old tale with a new twist

(2009) Byung Ha Lee et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Interleukin-12 induces salivary gland dysfunction in transgenic mice, providing a new model of Sjögren's syndrome

(2009) Jelle L. Vosters et al.   ARTHRITIS AND RHEUMATISM

Pathogenesis of Sjögrenʼs syndrome

(2009) Nikolay P Nikolov et al.   CURRENT OPINION IN RHEUMATOLOGY

B-cell-activating factor expressions in salivary epithelial cells after dsRNA virus infection depends on RNA-activated protein kinase activation

(2009) Marc Ittah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Primary Sjögren's Syndrome: health experiences and predictors of health quality among patients in the United States

(2009) Barbara Segal et al.   Health and Quality of Life Outcomes

Hepatic Interleukin-7 Expression Regulates T Cell Responses

(2009) Yukihisa Sawa et al.   IMMUNITY

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells

(2009) Stephen McCartney et al.   JOURNAL OF EXPERIMENTAL MEDICINE

X-linked Foxp3 (Scurfy) Mutation Dominantly Inhibits Submandibular Gland Development and Inflammation Respectively through Adaptive and Innate Immune Mechanisms

(2009) R. Sharma et al.   JOURNAL OF IMMUNOLOGY

Differential gene expression in the salivary gland during development and onset of xerostomia in Sjögren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse

(2009) Cuong Q Nguyen et al.   ARTHRITIS RESEARCH & THERAPY

Salivary gland tissue expression of interleukin-23 and interleukin-17 in Sjögren's syndrome: Findings in humans and mice

(2008) Cuong Q. Nguyen et al.   ARTHRITIS AND RHEUMATISM

MDA5/RIG-I and virus recognition

(2008) Osamu Takeuchi et al.   CURRENT OPINION IN IMMUNOLOGY

Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways

(2008) Marc Ittah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

(2008) T. Calzascia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA