Autoimmune manifestations in aged mice arise from early-life immune dysregulation

A Novel, Blocking, Fc-Silent Anti-CD40 Monoclonal Antibody Prolongs Nonhuman Primate Renal Allograft Survival in the Absence of B Cell Depletion

(2015) F. Cordoba et al.   AMERICAN JOURNAL OF TRANSPLANTATION

First-in-human trial of the safety, pharmacokinetics and immunogenicity of a PEGylated anti-CD40L antibody fragment (CDP7657) in healthy individuals and patients with systemic lupus erythematosus

(2015) A Tocoian et al.   LUPUS

Population dynamics of islet-infiltrating cells in autoimmune diabetes

(2015) Angela M. Magnuson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subclinical atherosclerosis and impaired bone health in patients with primary Sjogren’s syndrome: prevalence, clinical and laboratory associations

(2015) Fotini Gravani et al.   ARTHRITIS RESEARCH & THERAPY

Prediction of Sjögren's Syndrome Years Before Diagnosis and Identification of Patients With Early Onset and Severe Disease Course by Autoantibody Profiling

(2015) Elke Theander et al.   Arthritis & Rheumatology

Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjögren's syndrome

(2014) L. A. Aqrawi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

SerpinA3g participates in the antiadipogenesis and insulin-resistance induced by tumor necrosis factor-α in 3T3-F442A cells

(2014) Luis A. Salazar-Olivo et al.   CYTOKINE

A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis

(2014) Antonio Julià et al.   HUMAN MOLECULAR GENETICS

Discerning the kinetics of autoimmune manifestations in a model of Sjögren's syndrome

(2014) Jodi L. Karnell et al.   MOLECULAR IMMUNOLOGY

Germinal Center B Cell Depletion Diminishes CD4+ Follicular T Helper Cells in Autoimmune Mice

(2014) Isharat Yusuf et al.   PLoS One

Dynamic signaling by T follicular helper cells during germinal center B cell selection

(2014) Z. Shulman et al.   SCIENCE

Pharmacokinetics and Pharmacodynamics of ASKP1240, a Fully Human Anti-CD40 Antibody, in Normal and Renal Transplanted Cynomolgus Monkeys

(2014) Anlun Ma et al.   TRANSPLANTATION

Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype

(2013) Dirk Baumjohann et al.   IMMUNITY

Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4

(2013) Kyoko Ochiai et al.   IMMUNITY

Autoantibodies Present Before Symptom Onset in Primary Sjögren Syndrome

(2013) Roland Jonsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Circadian Clock in Oral Health and Diseases

(2013) S. Papagerakis et al.   JOURNAL OF DENTAL RESEARCH

Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse

(2013) Javier A. Carrero et al.   PLoS One

B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells

(2012) Matthieu Mahévas et al.   JOURNAL OF CLINICAL INVESTIGATION

Bcl6 and Maf Cooperate To Instruct Human Follicular Helper CD4 T Cell Differentiation

(2012) M. A. Kroenke et al.   JOURNAL OF IMMUNOLOGY

Local Administration of Soluble CD40:Fc to the Salivary Glands of Non-Obese Diabetic Mice Does Not Ameliorate Autoimmune Inflammation

(2012) Nienke Roescher et al.   PLoS One

The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions

(2011) C. Costa et al.   BLOOD

Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies

(2011) David V. Serreze et al.   DIABETES

Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjögren’s syndrome

(2011) N Roescher et al.   ORAL DISEASES

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

The meaning of anti-Ro and anti-La antibodies in primary Sjögren's syndrome

(2010) Gabriela Hernández-Molina et al.   AUTOIMMUNITY REVIEWS

Mzb1 Protein Regulates Calcium Homeostasis, Antibody Secretion, and Integrin Activation in Innate-like B Cells

(2010) Henrik Flach et al.   IMMUNITY

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease

(2010) John P. Driver et al.   Seminars in Immunopathology

Sex Differences in a Murine Model of Sjögren's Syndrome

(2009) Daniela Čiháková et al.   Annals of the New York Academy of Sciences

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

Primary Sjögren Syndrome in Spain

(2009) Manuel Ramos-Casals et al.   MEDICINE

Structural characterization of a human Fc fragment engineered for lack of effector functions

(2008) Vaheh Oganesyan et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Interferon-  initiates type 1 diabetes in nonobese diabetic mice

(2008) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA