Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway

Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjögren’s Syndrome-like Autoimmune Disease

(2013) Atsushi Okuma et al.   IMMUNITY

Innate Immune Signaling Induces Interleukin-7 Production from Salivary Gland Cells and Accelerates the Development of Primary Sjӧgren’s Syndrome in a Mouse Model

(2013) Jun-O Jin et al.   PLoS One

Pathogenesis of Sjögren’s syndrome: What we know and what we should learn

(2012) Athanasios G. Tzioufas et al.   JOURNAL OF AUTOIMMUNITY

The immunobiology of Ro52 (TRIM21) in autoimmunity: A critical review

(2012) Vilija Oke et al.   JOURNAL OF AUTOIMMUNITY

Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling

(2012) Seshagiri-Rao Nandula et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases

(2012) J. C. Hall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren’s syndrome-like disease

(2011) S-R Nandula et al.   ORAL DISEASES

Salivary epithelial cells from Sjogren’s syndrome patients are highly sensitive to anoikis induced by TLR-3 ligation

(2010) Menelaos N. Manoussakis et al.   JOURNAL OF AUTOIMMUNITY

Activation of the type I interferon pathway in primary Sjogren’s syndrome

(2010) Clio P. Mavragani et al.   JOURNAL OF AUTOIMMUNITY

Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function

(2010) Umesh S. Deshmukh et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

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(2010) John Routsias et al.   MOLECULAR MEDICINE

Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogren's syndrome

(2009) P. Vogelsang et al.   ANNALS OF THE RHEUMATIC DISEASES

Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome

(2009) Maria I. Christodoulou et al.   JOURNAL OF AUTOIMMUNITY

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

(2009) Alexander Espinosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRIM21 Is Essential to Sustain IFN Regulatory Factor 3 Activation during Antiviral Response

(2009) K. Yang et al.   JOURNAL OF IMMUNOLOGY

The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide

(2008) Alexander Espinosa et al.   EXPERIMENTAL CELL RESEARCH

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

(2008) H. Negishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA