Transcription Factor SmWRKY1 Positively Promotes the Biosynthesis of Tanshinones in Salvia miltiorrhiza

A WRKY transcription factor from Withania somnifera regulates triterpenoid withanolide accumulation and biotic stress tolerance through modulation of phytosterol and defense pathways

(2017) Anup Kumar Singh et al.   NEW PHYTOLOGIST

Overexpression of SmMYB9b enhances tanshinone concentration in Salvia miltiorrhiza hairy roots

(2017) Jingxian Zhang et al.   PLANT CELL REPORTS

Overexpression of NtWRKY50 Increases Resistance to Ralstonia solanacearum and Alters Salicylic Acid and Jasmonic Acid Production in Tobacco

(2017) Qiuping Liu et al.   Frontiers in Plant Science

Comprehensive transcriptome profiling of Salvia miltiorrhiza for discovery of genes associated with the biosynthesis of tanshinones and phenolic acids

(2017) Wei Zhou et al.   Scientific Reports

Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering

(2016) Min Shi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular cloning and characterization of two 1-deoxy-d-xylulose-5-phosphate synthase genes involved in tanshinone biosynthesis in Salvia miltiorrhiza

(2016) Wei Zhou et al.   MOLECULAR BREEDING

GLANDULAR TRICHOME-SPECIFIC WRKY 1 promotes artemisinin biosynthesis in Artemisia annua

(2016) Minghui Chen et al.   NEW PHYTOLOGIST

Mapping of Ppd-B1, a Major Candidate Gene for Late Heading on Wild Emmer Chromosome Arm 2BS and Assessment of Its Interactions with Early Heading QTLs on 3AL

(2016) Wei Zhou et al.   PLoS One

Overexpression ofAaWRKY1Leads to an Enhanced Content of Artemisinin inArtemisia annua

(2016) Weimin Jiang et al.   Biomed Research International

WRKY Transcription Factors: Molecular Regulation and Stress Responses in Plants

(2016) Ujjal J. Phukan et al.   Frontiers in Plant Science

Metabolic regulation and genetic engineering of pharmaceutical component tanshinone biosynthesis in Salvia miltiorrhiza

(2016) Xu Hui et al.   Journal of Medicinal Plants Research

Methyl jasmonate induction of tanshinone biosynthesis in Salvia miltiorrhiza hairy roots is mediated by JASMONATE ZIM-DOMAIN repressor proteins

(2016) Min Shi et al.   Scientific Reports

SmMYC2a and SmMYC2b played similar but irreplaceable roles in regulating the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza

(2016) Yangyun Zhou et al.   Scientific Reports

Molecular cloning and expression analysis of jasmonic acid dependent but salicylic acid independent LeWRKY1

(2015) M. Lu et al.   GENETICS AND MOLECULAR RESEARCH

Enhancing diterpenoid concentration inSalvia miltiorrhizahairy roots through pathway engineering with maize C1 transcription factor

(2015) Shujuan Zhao et al.   JOURNAL OF EXPERIMENTAL BOTANY

Overexpression ofSpWRKY1promotes resistance toPhytophthora nicotianaeand tolerance to salt and drought stress in transgenic tobacco

(2015) Jing-bin Li et al.   PHYSIOLOGIA PLANTARUM

In vitro inhibitory effects of ethanol extract of Danshen (Salvia miltiorrhiza) and its components on the catalytic activity of soluble epoxide hydrolase

(2015) Meijuan Xu et al.   PHYTOMEDICINE

GmWRKY27 interacts with GmMYB174 to reduce expression ofGmNAC29for stress tolerance in soybean plants

(2015) Fang Wang et al.   PLANT JOURNAL

GhWRKY25, a group I WRKY gene from cotton, confers differential tolerance to abiotic and biotic stresses in transgenic Nicotiana benthamiana

(2015) Xiufang Liu et al.   PROTOPLASMA

Effects of methyl jasmonate and salicylic acid on tanshinone production and biosynthetic gene expression in transgenicSalvia miltiorrhizahairy roots

(2014) Xiaolong Hao et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Increased accumulation of the cardio-cerebrovascular disease treatment drug tanshinone in Salvia miltiorrhiza hairy roots by the enzymes 3-hydroxy-3-methylglutaryl CoA reductase and 1-deoxy-d-xylulose 5-phosphate reductoisomerase

(2014) Min Shi et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts

(2013) J. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanism of elicitor-induced tanshinone accumulation in Salvia miltiorrhiza hairy root cultures

(2012) Guoyin Kai et al.   ACTA PHYSIOLOGIAE PLANTARUM

Tanshinones Inhibit the Growth of Breast Cancer Cells through Epigenetic Modification of Aurora A Expression and Function

(2012) Yi Gong et al.   PLoS One

Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures

(2011) Guoyin Kai et al.   METABOLIC ENGINEERING

Tanshinone�IIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo

(2011) Liang Zhong   ONCOLOGY REPORTS

The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

(2011) N. Suttipanta et al.   PLANT PHYSIOLOGY

Molecular cloning and expression analysis of a new putative gene encoding 3-hydroxy-3-methylglutaryl-CoA synthase from Salvia miltiorrhiza

(2010) Lin Zhang et al.   ACTA PHYSIOLOGIAE PLANTARUM

Characterization, expression profiling, and functional identification of a gene encoding geranylgeranyl diphosphate synthase from Salvia miltiorrhiza

(2010) Guoyin Kai et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents

(2010) Yuan Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Salvia miltiorrhiza involved in diterpenoid tanshinone accumulation

(2010) Zhubo Dai et al.   JOURNAL OF PLANT PHYSIOLOGY

WRKY transcription factors

(2010) Paul J. Rushton et al.   TRENDS IN PLANT SCIENCE

Molecular characterization and expression of 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) gene from Salvia miltiorrhiza

(2009) Xiangming Yan et al.   ACTA PHYSIOLOGIAE PLANTARUM

A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights

(2009) Wei Gao et al.   ORGANIC LETTERS

Isolation and Characterization of AaWRKY1, an Artemisia annua Transcription Factor that Regulates the Amorpha-4,11-diene Synthase Gene, a Key Gene of Artemisinin Biosynthesis

(2009) Dongming Ma et al.   PLANT AND CELL PHYSIOLOGY