CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts

Downstream reactions and engineering in the microbially reconstituted pathway for Taxol

(2012) Ming Jiang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Impacts of Diversification of Cytochrome P450 on Plant Metabolism

(2012) Masaharu Mizutani   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Characterization of CYP76M5–8 Indicates Metabolic Plasticity within a Plant Biosynthetic Gene Cluster

(2012) Qiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza

(2012) Yimian Ma et al.   JOURNAL OF EXPERIMENTAL BOTANY

Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

(2012) Yongjin J. Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7

(2011) Yisheng Wu et al.   FEBS LETTERS

Convergence: Where West meets East

(2011) Peng Tian   NATURE

Modernization: One step at a time

(2011) Zhiguo Xu   NATURE

Evolution of Diterpene Metabolism: Sitka Spruce CYP720B4 Catalyzes Multiple Oxidations in Resin Acid Biosynthesis of Conifer Defense against Insects

(2011) B. Hamberger et al.   PLANT PHYSIOLOGY

Diversification of P450 Genes During Land Plant Evolution

(2010) Masaharu Mizutani et al.   Annual Review of Plant Biology

Tanshinone biosynthesis in Salvia miltiorrhiza and production in plant tissue cultures

(2010) Jian Wen Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Candidate genes involved in tanshinone biosynthesis in hairy roots of Salvia miltiorrhiza revealed by cDNA microarray

(2010) Guanghong Cui et al.   MOLECULAR BIOLOGY REPORTS

Two rings in them all: The labdane-related diterpenoids

(2010) Reuben J. Peters   NATURAL PRODUCT REPORTS

CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice

(2010) Qiang Wang et al.   PLANT JOURNAL

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

Biosynthesis of Plant Isoprenoids: Perspectives for Microbial Engineering

(2009) James Kirby et al.   Annual Review of Plant Biology

Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering

(2009) Dana Morrone et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights

(2009) Wei Gao et al.   ORGANIC LETTERS

CYP76M7 Is an ent-Cassadiene C11 -Hydroxylase Defining a Second Multifunctional Diterpenoid Biosynthetic Gene Cluster in Rice

(2009) S. Swaminathan et al.   PLANT CELL

Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells

(2008) Marcelo Bispo de Jesus et al.   BIOCHIMIE