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Title
Harnessing the mTOR Pathway for Tuberculosis Treatment
Authors
Keywords
-
Journal
Frontiers in Microbiology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-01-30
DOI
10.3389/fmicb.2018.00070
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Note: Only part of the references are listed.- Inhibition of the PI3K-Akt-mTOR signaling pathway in T lymphocytes in patients with active tuberculosis
- (2017) XueXuan Zhang et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
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- (2017) Aditya Sharma et al. LANCET INFECTIOUS DISEASES
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- (2017) Filipe Palavra et al. Oxidative Medicine and Cellular Longevity
- Eastern Canadian Gastrointestinal Cancer Consensus Conference 2016
- (2016) D. Bossé et al. Current Oncology
- mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
- (2016) Hu Zeng et al. IMMUNITY
- Autophagy induction targeting mTORC1 enhances Mycobacterium tuberculosis replication in HIV co-infected human macrophages
- (2016) Anna-Maria Andersson et al. Scientific Reports
- Cellular and molecular effects of the mTOR inhibitor everolimus
- (2015) U. Saran et al. CLINICAL SCIENCE
- Clinical efficacy of mTOR inhibitors in solid tumors: a systematic review
- (2015) Zebo Huang et al. Future Oncology
- Towards host-directed therapies for tuberculosis
- (2015) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- Differentiating the mTOR inhibitors everolimus and sirolimus in the treatment of tuberous sclerosis complex
- (2015) Jeffrey P. MacKeigan et al. NEURO-ONCOLOGY
- Regulation of mTORC1 by PI3K signaling
- (2015) Christian C. Dibble et al. TRENDS IN CELL BIOLOGY
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- (2015) Jolanta Barbara Fijałkowska-Morawska et al. Annals of Transplantation
- Mycobacterium tuberculosis Inhibits RAB7 Recruitment to Selectively Modulate Autophagy Flux in Macrophages
- (2015) Pallavi Chandra et al. Scientific Reports
- Bacterial Pathogen Manipulation of Host Membrane Trafficking
- (2014) Seblewongel Asrat et al. Annual Review of Cell and Developmental Biology
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- Combination of the mTOR Inhibitor Ridaforolimus and the Anti-IGF1R Monoclonal Antibody Dalotuzumab: Preclinical Characterization and Phase I Clinical Trial
- (2014) S. Di Cosimo et al. CLINICAL CANCER RESEARCH
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- (2014) J. B. Mannick et al. Science Translational Medicine
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- (2014) H. B. Yu et al. mBio
- Autophagy Adaptor Protein p62/SQSTM1 and Autophagy-Related Gene Atg5 Mediate Autophagosome Formation in Response to Mycobacterium tuberculosis Infection in Dendritic Cells
- (2013) Shintaro Seto et al. PLoS One
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- (2013) Evelyn Guirado et al. Seminars in Immunopathology
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- (2012) Y. Koh et al. ANNALS OF ONCOLOGY
- Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections
- (2012) David M. Tobin et al. CELL
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- (2012) Mathieu Laplante et al. CELL
- Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action
- (2012) Jwa-Jin Kim et al. Cell Host & Microbe
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- (2012) Shintaro Seto et al. CELLULAR MICROBIOLOGY
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- (2012) H. Pan et al. JOURNAL OF IMMUNOLOGY
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- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
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- (2012) A. Choy et al. SCIENCE
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- (2012) Mário Songane et al. TUBERCULOSIS
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- (2011) Selvakumar Subbian et al. AMERICAN JOURNAL OF PATHOLOGY
- The Role of Atg Proteins in Autophagosome Formation
- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress
- (2011) Shukie Ng et al. Autophagy
- Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma
- (2011) Camillo Porta et al. EUROPEAN JOURNAL OF CANCER
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- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2011) V. M. Rivera et al. MOLECULAR CANCER THERAPEUTICS
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- (2011) Beth Levine et al. NATURE
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- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
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- (2011) A. Parkhitko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) L. Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) L. Guenin-Macé et al. Transboundary and Emerging Diseases
- Autophagy: For Better or for Worse, in Good Times or in Bad Times …
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- The TSC1-TSC2 Complex Is Required for Proper Activation of mTOR Complex 2
- (2008) J. Huang et al. MOLECULAR AND CELLULAR BIOLOGY
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