Phosphodiesterase-4 Inhibition Alters Gene Expression and Improves Isoniazid – Mediated Clearance of Mycobacterium tuberculosis in Rabbit Lungs
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phosphodiesterase-4 Inhibition Alters Gene Expression and Improves Isoniazid – Mediated Clearance of Mycobacterium tuberculosis in Rabbit Lungs
Authors
Keywords
Mycobacterium tuberculosis, Rabbits, Gene expression, Immune response, Macrophages, Respiratory infections, Tuberculosis, Granulomas
Journal
PLoS Pathogens
Volume 7, Issue 9, Pages e1002262
Publisher
Public Library of Science (PLoS)
Online
2011-09-16
DOI
10.1371/journal.ppat.1002262
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel Inhibitors of InhA Efficiently KillMycobacterium tuberculosisunder Aerobic and Anaerobic Conditions
- (2011) Catherine Vilchèze et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism
- (2011) Kristin N. Adams et al. CELL
- Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch
- (2011) Santosh Chauhan et al. NUCLEIC ACIDS RESEARCH
- Phosphodiesterase 4 Inhibition Reduces Innate Immunity and Improves Isoniazid Clearance of Mycobacterium tuberculosis in the Lungs of Infected Mice
- (2011) Mi-Sun Koo et al. PLoS One
- Pharmacology of TNF blockade in rheumatoid arthritis and other chronic inflammatory diseases
- (2010) Peter C Taylor CURRENT OPINION IN PHARMACOLOGY
- Tumor Necrosis Factor-α Monoclonal Antibodies in the Treatment of Inflammatory Bowel Disease: Clinical Practice Pharmacology
- (2010) Thomas W. Lee et al. GASTROENTEROLOGY CLINICS OF NORTH AMERICA
- The SigF Regulon in Mycobacterium smegmatis Reveals Roles in Adaptation to Stationary Phase, Heat, and Oxidative Stress
- (2010) A. Humpel et al. JOURNAL OF BACTERIOLOGY
- Genetic Requirements for the Survival of Tubercle Bacilli in Primates
- (2010) Noton K. Dutta et al. JOURNAL OF INFECTIOUS DISEASES
- The Stringent Response Is Required for Full Virulence ofMycobacterium tuberculosisin Guinea Pigs
- (2010) Lee G. Klinkenberg et al. JOURNAL OF INFECTIOUS DISEASES
- The Population Dynamics and Control of Tuberculosis
- (2010) C. Dye et al. SCIENCE
- Functional Genetic Diversity among Mycobacterium tuberculosis Complex Clinical Isolates: Delineation of Conserved Core and Lineage-Specific Transcriptomes during Intracellular Survival
- (2010) Susanne Homolka et al. PLoS Pathogens
- Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis
- (2009) PH Schafer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Recognizing Macrophage Activation and Host Defense
- (2009) John D. MacMicking Cell Host & Microbe
- Mycobacterial survival strategies in the phagosome: defence against host stresses
- (2009) Sabine Ehrt et al. CELLULAR MICROBIOLOGY
- Penitentiary or penthouse condo: the tuberculous granuloma from the microbe's point of view
- (2009) Carleitta Paige et al. CELLULAR MICROBIOLOGY
- The sigma factors of Mycobacterium tuberculosis: regulation of the regulators
- (2009) Preeti Sachdeva et al. FEBS Journal
- Adjusting to a new home:Mycobacterium tuberculosisgene expression in response to an intracellular lifestyle
- (2009) Richard W Stokes et al. Future Microbiology
- The many niches and strategies used by pathogenic mycobacteria for survival within host macrophages
- (2009) Chantal de Chastellier IMMUNOBIOLOGY
- The Mycobacterium tuberculosis DosR Regulon Assists in Metabolic Homeostasis and Enables Rapid Recovery from Nonrespiring Dormancy
- (2009) R. L. Leistikow et al. JOURNAL OF BACTERIOLOGY
- Neutralization of TNFα alters inflammation in guinea pig tuberculous pleuritis
- (2009) Lan H. Ly et al. MICROBES AND INFECTION
- Microarray Analysis of Efflux Pump Genes in Multidrug-Resistant Mycobacterium tuberculosis During Stress Induced by Common Anti-Tuberculous Drugs
- (2009) Anuj Kumar Gupta et al. Microbial Drug Resistance
- The Mycobacterium bovis Bacille Calmette-Guérin Phagosome Proteome
- (2009) Bai-Yu Lee et al. MOLECULAR & CELLULAR PROTEOMICS
- Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase
- (2009) Nisheeth Agarwal et al. NATURE
- The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
- (2009) Shengli Hao et al. NATURE IMMUNOLOGY
- Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
- (2009) Ronald S. Flannagan et al. NATURE REVIEWS MICROBIOLOGY
- A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen
- (2009) Chirajyoti Deb et al. PLoS One
- The DosR regulon of M. tuberculosis and antibacterial tolerance
- (2009) I.L. Bartek et al. TUBERCULOSIS
- Cyclic AMP
- (2008) Carlos H. Serezani et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- PDE4 inhibitors: current status
- (2008) D Spina BRITISH JOURNAL OF PHARMACOLOGY
- Mycobacterium tuberculosis and the Macrophage: Maintaining a Balance
- (2008) Jean Pieters Cell Host & Microbe
- Mycobacterium tuberculosis Senses Host-Derived Carbon Monoxide during Macrophage Infection
- (2008) Michael U. Shiloh et al. Cell Host & Microbe
- Insights into the regulation of TNF-a production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition
- (2008) Jessica Deree et al. Clinics
- Human macrophage host defense against Mycobacterium tuberculosis
- (2008) Philip T Liu et al. CURRENT OPINION IN IMMUNOLOGY
- Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models
- (2008) P. J. Converse et al. INFECTION AND IMMUNITY
- Tumor Necrosis Factor Blockade in Chronic Murine Tuberculosis Enhances Granulomatous Inflammation and Disorganizes Granulomas in the Lungs
- (2008) S. D. Chakravarty et al. INFECTION AND IMMUNITY
- Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates
- (2008) L. E. Via et al. INFECTION AND IMMUNITY
- Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants
- (2008) Benjamin E. Steinberg et al. JOURNAL OF CLINICAL INVESTIGATION
- Mycobacterium tuberculosisSigma Factor E Regulon Modulates the Host Inflammatory Response
- (2008) Patricia A. Fontán et al. JOURNAL OF INFECTIOUS DISEASES
- Quantitative Proteomic Profiling of Host−Pathogen Interactions: The Macrophage Response toMycobacterium tuberculosisLipids
- (2008) Wenqing Shui et al. JOURNAL OF PROTEOME RESEARCH
- Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages
- (2008) Ludovic Tailleux et al. PLoS One
- Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model
- (2008) Anup K. Kesavan et al. TUBERCULOSIS
- Identification of Tuberculosis Susceptibility Genes with Human Macrophage Gene Expression Profiles
- (2008) Nguyen Thuy Thuong Thuong et al. PLoS Pathogens
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now