The diagnosis of progressive supranuclear palsy: current opinions and challenges

[18F] AV-1451 uptake in corticobasal syndrome: the influence of beta-amyloid and clinical presentation

(2018) F. Ali et al.   JOURNAL OF NEUROLOGY

Tracking brain damage in progressive supranuclear palsy: a longitudinal MRI study

(2018) Federica Agosta et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Lifetime exposure to estrogen and progressive supranuclear palsy: Environmental and Genetic PSP study

(2018) Hee Kyung Park et al.   MOVEMENT DISORDERS

Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies

(2018) Jose-Alberto Palma et al.   MOVEMENT DISORDERS

Beyond ALS and FTD: the phenotypic spectrum of TBK1 mutations includes PSP-like and cerebellar phenotypes

(2018) Carlo Wilke et al.   NEUROBIOLOGY OF AGING

Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration

(2018) Sang Won Seo et al.   NEUROLOGY

The diagnostic accuracy of the hummingbird and morning glory sign in patients with neurodegenerative parkinsonism

(2018) Christoph Mueller et al.   PARKINSONISM & RELATED DISORDERS

Pittsburgh Compound B and AV-1451 positron emission tomography assessment of molecular pathologies of Alzheimer's disease in progressive supranuclear palsy

(2018) Jennifer L. Whitwell et al.   PARKINSONISM & RELATED DISORDERS

Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies

(2017) Jianlan Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predictors of survival in progressive supranuclear palsy and multiple system atrophy: a systematic review and meta-analysis

(2017) Stella Andrea Glasmacher et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Preclinical Evaluation of 18 F-JNJ64349311, a Novel PET Tracer for Tau Imaging

(2017) Lieven Declercq et al.   JOURNAL OF NUCLEAR MEDICINE

Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria

(2017) Günter U. Höglinger et al.   MOVEMENT DISORDERS

Intrinsic functional connectivity alterations in progressive supranuclear palsy: Differential effects in frontal cortex, motor, and midbrain networks

(2017) Johannes Rosskopf et al.   MOVEMENT DISORDERS

Longitudinal magnetic resonance imaging in progressive supranuclear palsy: A new combined score for clinical trials

(2017) Günter U. Höglinger et al.   MOVEMENT DISORDERS

Which ante mortem clinical features predict progressive supranuclear palsy pathology?

(2017) Gesine Respondek et al.   MOVEMENT DISORDERS

CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP

(2017) Julio C. Rojas et al.   NEUROLOGY

Palliative care and its emerging role in Multiple System Atrophy and Progressive Supranuclear Palsy

(2017) Louise Wiblin et al.   PARKINSONISM & RELATED DISORDERS

Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy

(2017) Sarah L. DeVos et al.   Science Translational Medicine

Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains

(2017) Laetitia Lemoine et al.   Alzheimers Research & Therapy

Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms

(2017) Andrew Kneynsberg et al.   Frontiers in Neuroscience

Rehabilitation in progressive supranuclear palsy: Effectiveness of two multidisciplinary treatments

(2017) Ilaria Clerici et al.   PLoS One

Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer’s disease and progressive supranuclear palsy brains

(2017) Vincent Huin et al.   Scientific Reports

Tau neuropathology correlates with FDG-PET, but not AV-1451-PET, in progressive supranuclear palsy

(2016) Ruben Smith et al.   ACTA NEUROPATHOLOGICA

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci

(2016) Mariet Allen et al.   ACTA NEUROPATHOLOGICA

Characterization of tau positron emission tomography tracer [ 18 F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias

(2016) Kerstin Sander et al.   Alzheimers & Dementia

Progressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment Options

(2016) Ruth Lamb et al.   Current Treatment Options in Neurology

Tau physiology and pathomechanisms in frontotemporal lobar degeneration

(2016) Liviu-Gabriel Bodea et al.   JOURNAL OF NEUROCHEMISTRY

The clinical spectrum and natural history of pure akinesia with gait freezing

(2016) Emily Owens et al.   JOURNAL OF NEUROLOGY

Atypical parkinsonism in C9orf72 expansions: a case report and systematic review of 45 cases from the literature

(2016) Carlo Wilke et al.   JOURNAL OF NEUROLOGY

Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

(2016) E. D. Hostetler et al.   JOURNAL OF NUCLEAR MEDICINE

Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP-C

(2016) Shunsuke Koga et al.   MOVEMENT DISORDERS

Environmental and occupational risk factors for progressive supranuclear palsy: Case-control study

(2016) Irene Litvan et al.   MOVEMENT DISORDERS

Distribution and characteristics of transactive response DNA binding protein 43 kDa pathology in progressive supranuclear palsy

(2016) Shunsuke Koga et al.   MOVEMENT DISORDERS

[18F]AV-1451 tau positron emission tomography in progressive supranuclear palsy

(2016) Jennifer L. Whitwell et al.   MOVEMENT DISORDERS

Subcortical18F-AV-1451 binding patterns in progressive supranuclear palsy

(2016) Hanna Cho et al.   MOVEMENT DISORDERS

Increased basal ganglia binding of18F-AV-1451 in patients with progressive supranuclear palsy

(2016) Ruben Smith et al.   MOVEMENT DISORDERS

Regional expression of the MAPT gene is associated with loss of hubs in brain networks and cognitive impairment in Parkinson disease and progressive supranuclear palsy

(2016) Timothy Rittman et al.   NEUROBIOLOGY OF AGING

Progression of brain atrophy in PSP and CBS over 6 months and 1 year

(2016) Shubir Dutt et al.   NEUROLOGY

Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes

(2016) Ian T.S. Coyle-Gilchrist et al.   NEUROLOGY

MR parkinsonism index predicts vertical supranuclear gaze palsy in patients with PSP–parkinsonism

(2016) Aldo Quattrone et al.   NEUROLOGY

Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model

(2016) Kathleen M. Schoch et al.   NEURON

The phenotypic spectrum of progressive supranuclear palsy

(2016) G. Respondek et al.   PARKINSONISM & RELATED DISORDERS

DCTN1 p.K56R in progressive supranuclear palsy

(2016) Emil K. Gustavsson et al.   PARKINSONISM & RELATED DISORDERS

Highly specific radiographic marker predates clinical diagnosis in progressive supranuclear palsy

(2016) Emily Owens et al.   PARKINSONISM & RELATED DISORDERS

Prevalence of progressive supranuclear palsy in Yonago: change throughout a decade

(2016) Hiroshi Takigawa et al.   Brain and Behavior

Discriminating among degenerative parkinsonisms using advanced 123 I-ioflupane SPECT analyses

(2016) Simon Badoud et al.   NeuroImage-Clinical

Plasma neurofilament light chain predicts progression in progressive supranuclear palsy

(2016) Julio C. Rojas et al.   Annals of Clinical and Translational Neurology

An autoradiographic evaluation of AV-1451 Tau PET in dementia

(2016) Val J. Lowe et al.   Acta Neuropathologica Communications

An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability

(2016) Carolin Kurz et al.   Acta Neuropathologica Communications

Progression of Microstructural Degeneration in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Longitudinal Diffusion Tensor Imaging Study

(2016) Yu Zhang et al.   PLoS One

Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

(2015) Marta Marquié et al.   ANNALS OF NEUROLOGY

Cascading network failure across the Alzheimer’s disease spectrum

(2015) David T. Jones et al.   BRAIN

Progressive supranuclear palsy: progression and survival

(2015) Julieta E. Arena et al.   JOURNAL OF NEUROLOGY

The Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and Therapy

(2015) Cheng-Cheng Zhang et al.   MOLECULAR NEUROBIOLOGY

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

(2015) Meaghan Morris et al.   NATURE NEUROSCIENCE

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Atypical Parkinsonism

(2015) Maria Stamelou et al.   NEUROLOGIC CLINICS

A geographical cluster of progressive supranuclear palsy in northern France

(2015) Dominique Caparros-Lefebvre et al.   NEUROLOGY

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

(2015) Yingjun Zhao et al.   NEURON

Three sib-pairs of autopsy-confirmed progressive supranuclear palsy

(2015) Shinsuke Fujioka et al.   PARKINSONISM & RELATED DISORDERS

Tau immunotherapy for Alzheimer's disease

(2015) Jan Torleif Pedersen et al.   TRENDS IN MOLECULAR MEDICINE

Early Stage of Progressive Supranuclear Palsy: A Neuropathological Study of 324 Consecutive Autopsy Cases

(2015) Akane Nogami et al.   JOURNAL OF NIPPON MEDICAL SCHOOL

The evolution of primary progressive apraxia of speech

(2014) Keith A. Josephs et al.   BRAIN

Clinical outcomes of two main variants of progressive supranuclear palsy and multiple system atrophy: a prospective natural history study

(2014) Milica Jecmenica-Lukic et al.   JOURNAL OF NEUROLOGY

Clinical, cognitive, and behavioural correlates of white matter damage in progressive supranuclear palsy

(2014) Federica Agosta et al.   JOURNAL OF NEUROLOGY

FDG-PET in pathologically confirmed spontaneous 4R-tauopathy variants

(2014) Nicholas Zalewski et al.   JOURNAL OF NEUROLOGY

Clinicopathological Outcomes of Prospectively Followed Normal Elderly Brain Bank Volunteers

(2014) Brittany N. Dugger et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

(2014) Adam L Boxer et al.   LANCET NEUROLOGY

A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy

(2014) Eduardo Tolosa et al.   MOVEMENT DISORDERS

Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial

(2014) Günter U. Höglinger et al.   MOVEMENT DISORDERS

The phenotypic spectrum of progressive supranuclear palsy: A retrospective multicenter study of 100 definite cases

(2014) Gesine Respondek et al.   MOVEMENT DISORDERS

The use of botulinum toxin in the treatment of sialorrhea in parkinsonian disorders

(2014) María T. Gómez-Caravaca et al.   NEUROLOGICAL SCIENCES

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Diffusion tensor imaging comparison of progressive supranuclear palsy and corticobasal syndromes

(2014) Jennifer L. Whitwell et al.   PARKINSONISM & RELATED DISORDERS

Concomitant pathologies among a spectrum of parkinsonian disorders

(2014) Brittany N. Dugger et al.   PARKINSONISM & RELATED DISORDERS

Diffusion Tensor Imaging of Parkinson’s Disease, Multiple System Atrophy and Progressive Supranuclear Palsy: A Tract-Based Spatial Statistics Study

(2014) Amanda Worker et al.   PLoS One

Globular glial tauopathies (GGT): consensus recommendations

(2013) Zeshan Ahmed et al.   ACTA NEUROPATHOLOGICA

[18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

(2013) Chun-Fang Xia et al.   Alzheimers & Dementia

Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies

(2013) David J. Irwin et al.   AMERICAN JOURNAL OF PATHOLOGY

Intrinsic connectivity network disruption in progressive supranuclear palsy

(2013) Raquel C. Gardner et al.   ANNALS OF NEUROLOGY

Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration

(2013) Carole S. Scherling et al.   ANNALS OF NEUROLOGY

Midbrain atrophy is not a biomarker of progressive supranuclear palsy pathology

(2013) J. L. Whitwell et al.   EUROPEAN JOURNAL OF NEUROLOGY

Validation of parkinsonian disease-related metabolic brain patterns

(2013) Laura K. Teune et al.   MOVEMENT DISORDERS

Accuracy of the national institute for neurological disorders and stroke/society for progressive supranuclear palsy and neuroprotection and natural history in Parkinson plus syndromes criteria for the diagnosis of progressive supranuclear palsy

(2013) Gesine Respondek et al.   MOVEMENT DISORDERS

Criteria for the diagnosis of corticobasal degeneration

(2013) M. J. Armstrong et al.   NEUROLOGY

Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo

(2013) Kiran Yanamandra et al.   NEURON

Characteristics of progressive supranuclear palsy presenting with corticobasal syndrome: a cortical variant

(2013) H. Ling et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The pimple sign of progressive supranuclear palsy syndrome

(2013) Hugo Botha et al.   PARKINSONISM & RELATED DISORDERS

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Saccade Abnormalities in Autopsy-Confirmed Frontotemporal Lobar Degeneration and Alzheimer Disease

(2012) Siobhan Garbutt   ARCHIVES OF NEUROLOGY

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

(2012) Daniah Trabzuni et al.   HUMAN MOLECULAR GENETICS

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

(2012) Giovanni Coppola et al.   HUMAN MOLECULAR GENETICS

Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests

(2012) Valeria Iodice et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Subregional Patterns of Preferential Striatal Dopamine Transporter Loss Differ in Parkinson Disease, Progressive Supranuclear Palsy, and Multiple-System Atrophy

(2012) M. Oh et al.   JOURNAL OF NUCLEAR MEDICINE

Primary lateral sclerosis as progressive supranuclear palsy: Diagnosis by diffusion tensor imaging

(2012) Elizabeth A. Coon et al.   MOVEMENT DISORDERS

Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

(2012) Scott A Yuzwa et al.   Nature Chemical Biology

Diffusion tensor MRI contributes to differentiate Richardson's syndrome from PSP-parkinsonism

(2012) Federica Agosta et al.   NEUROBIOLOGY OF AGING

Nigro-striatal involvement in primary progressive freezing gait: Insights into a heterogeneous pathogenesis

(2012) Alfonso Fasano et al.   PARKINSONISM & RELATED DISORDERS

Clinical Correlates of White Matter Tract Degeneration in Progressive Supranuclear Palsy

(2011) Jennifer L. Whitwell et al.   ARCHIVES OF NEUROLOGY

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

(2011) Katya Rascovsky et al.   BRAIN

Distinctive Features of Saccadic Intrusions and Microsaccades in Progressive Supranuclear Palsy

(2011) J. Otero-Millan et al.   JOURNAL OF NEUROSCIENCE

Gray matter correlates of behavioral severity in progressive supranuclear palsy

(2011) Keith A. Josephs et al.   MOVEMENT DISORDERS

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

(2011) Günter U Höglinger et al.   NATURE GENETICS

Autopsy-proven progressive supranuclear palsy presenting as behavioral variant frontotemporal dementia

(2011) Anhar Hassan et al.   NEUROCASE

Disrupted thalamocortical connectivity in PSP: A resting-state fMRI, DTI, and VBM study

(2011) Jennifer L. Whitwell et al.   PARKINSONISM & RELATED DISORDERS

Neuropathological findings of PSP in the elderly without clinical PSP: Possible incidental PSP?

(2011) Virgilio Gerald H. Evidente et al.   PARKINSONISM & RELATED DISORDERS

Does corticobasal degeneration exist? A clinicopathological re-evaluation

(2010) H. Ling et al.   BRAIN

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Neuropathology of variants of progressive supranuclear palsy

(2010) Dennis W Dickson et al.   CURRENT OPINION IN NEUROLOGY

What features improve the accuracy of the clinical diagnosis of progressive supranuclear palsy-parkinsonism (PSP-P)?

(2010) David R Williams et al.   MOVEMENT DISORDERS

Preliminary studies of differential impairments of the dopaminergic system in subtypes of progressive supranuclear palsy

(2010) Wey-Yil Lin et al.   NUCLEAR MEDICINE COMMUNICATIONS

Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: The NNIPPS Study

(2008) Gilbert Bensimon et al.   BRAIN

Apraxia of speech and nonfluent aphasia: a new clinical marker for corticobasal degeneration and progressive supranuclear palsy

(2008) Keith A Josephs et al.   CURRENT OPINION IN NEUROLOGY

Short-term effects of coenzyme Q10 in progressive supranuclear palsy: A randomized, placebo-controlled trial

(2008) Maria Stamelou et al.   MOVEMENT DISORDERS

Diffusion tensor analysis of corpus callosum in progressive supranuclear palsy

(2008) Shoichi Ito et al.   NEURORADIOLOGY