The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation

Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway

(2018) Cheng Dong et al.   Nature Chemical Biology

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes

(2017) Shun-Jia Chen et al.   SCIENCE

Cell signalling pathway regulation by RanBPM: molecular insights and disease implications

(2017) Louisa M. Salemi et al.   Open Biology

MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation

(2017) X Jin et al.   Oncogenesis

Studies of recombinant TWA1 reveal constitutive dimerization

(2016) Ore Francis et al.   BIOSCIENCE REPORTS

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

(2016) Daniel C. Scott et al.   CELL

Drugging the undruggables: exploring the ubiquitin system for drug development

(2016) Xiaodong Huang et al.   CELL RESEARCH

CRL4 WDR23 -Mediated SLBP Ubiquitylation Ensures Histone Supply during DNA Replication

(2016) Mia M.L. Brodersen et al.   MOLECULAR CELL

The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation

(2016) Mehrpouya B. Mobin et al.   Nature Communications

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

CRL4RBBP7 is required for efficient CENP-A deposition at centromeres

(2015) J. Mouysset et al.   JOURNAL OF CELL SCIENCE

The LisH Motif of Muskelin Is Crucial for Oligomerization and Governs Intracellular Localization

(2015) Carolyn F. Delto et al.   STRUCTURE

New insights into ubiquitin E3 ligase mechanism

(2014) Christopher E Berndsen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Molecular Phylogeny of a RING E3 Ubiquitin Ligase, Conserved in Eukaryotic Cells and Dominated by Homologous Components, the Muskelin/RanBPM/CTLH Complex

(2013) Ore Francis et al.   PLoS One

RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer’s brain synaptosomes

(2013) J P Palavicini et al.   Cell Death & Disease

Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C)

(2012) Ziguo Zhang et al.   BIOCHEMICAL JOURNAL

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1

(2012) F Rizzolio et al.   CELL DEATH AND DIFFERENTIATION

Exploring the Topology of the Gid Complex, the E3 Ubiquitin Ligase Involved in Catabolite-induced Degradation of Gluconeogenic Enzymes

(2012) Ruth Menssen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HECT and RING finger families of E3 ubiquitin ligases at a glance

(2012) M. B. Metzger et al.   JOURNAL OF CELL SCIENCE

HBP1-Mediated Transcriptional Regulation of DNA Methyltransferase 1 and Its Impact on Cell Senescence

(2012) K. Pan et al.   MOLECULAR AND CELLULAR BIOLOGY

RanBPM is essential for mouse spermatogenesis and oogenesis

(2011) S. Puverel et al.   DEVELOPMENT

Control of Blood Glucose in the Absence of Hepatic Glucose Production During Prolonged Fasting in Mice: Induction of Renal and Intestinal Gluconeogenesis by Glucagon

(2011) E. Mutel et al.   DIABETES

Diverse roles of the scaffolding protein RanBPM

(2011) Bharathi Suresh et al.   DRUG DISCOVERY TODAY

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

(2011) Wenqing Jiang et al.   MOLECULAR CELL

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression

(2011) W. Wang et al.   NUCLEIC ACIDS RESEARCH

RNAi-based screening identifies the Mms22L–Nfkbil2 complex as a novel regulator of DNA replication in human cells

(2010) Wojciech Piwko et al.   EMBO JOURNAL

SAINT: probabilistic scoring of affinity purification–mass spectrometry data

(2010) Hyungwon Choi et al.   NATURE METHODS

Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence

(2010) H Li et al.   ONCOGENE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Is There Glucose Production Outside of the Liver and Kidney?

(2009) Stephen F. Previs et al.   Annual Review of Nutrition

The Yeast GID Complex, a Novel Ubiquitin Ligase (E3) Involved in the Regulation of Carbohydrate Metabolism

(2008) Olivier Santt et al.   MOLECULAR BIOLOGY OF THE CELL