MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation

Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma

(2016) H. Hirata et al.   CANCER RESEARCH

Oncogenic MAGEA-TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer

(2015) Carlos T Pineda et al.   Autophagy

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

(2015) Carlos T. Pineda et al.   CELL

The MAGE protein family and cancer

(2015) Jenny L Weon et al.   CURRENT OPINION IN CELL BIOLOGY

An aptamer targeting shared tumor-specific peptide antigen of MAGE-A3 in multiple cancers

(2015) Chin-Yu Wang et al.   INTERNATIONAL JOURNAL OF CANCER

TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification

(2015) Shu Hui Neo et al.   MOLECULAR AND CELLULAR BIOLOGY

NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells

(2015) Yi Zhu et al.   Oncotarget

KAP1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells

(2014) J. B. Addison et al.   CANCER RESEARCH

Emerging Potential of Therapeutic Targeting of Ubiquitin-Specific Proteases in the Treatment of Cancer

(2014) A. Pal et al.   CANCER RESEARCH

KAP-1 is overexpressed and correlates with increased metastatic ability and tumorigenicity in pancreatic cancer

(2014) Chao Yu et al.   MEDICAL ONCOLOGY

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

(2014) Bo Li et al.   NATURE

Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

(2013) Chenfang Dong et al.   CANCER CELL

Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

(2013) Shauna N. Vasilatos et al.   CARCINOGENESIS

Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination

(2013) Yi-Heng Hao et al.   CELL

BRCA1 is a negative modulator of the PRC2 complex

(2013) Lan Wang et al.   EMBO JOURNAL

Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model

(2012) Cun Wang et al.   BMC CANCER

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

(2012) Brandon Faubert et al.   Cell Metabolism

Increased apoptosis induction in hepatocellular carcinoma by a novel tumor-targeted TRAIL fusion protein combined with bortezomib

(2012) Kristin Wahl et al.   HEPATOLOGY

Proliferative activity in hepatocellular carcinoma is closely correlated with glucose metabolism but not angiogenesis

(2011) Koji Kitamura et al.   JOURNAL OF HEPATOLOGY

Tripartite Motif-Containing Protein 28 Is a Small Ubiquitin-Related Modifier E3 Ligase and Negative Regulator of IFN Regulatory Factor 7

(2011) Q. Liang et al.   JOURNAL OF IMMUNOLOGY

When MAGE meets RING: insights into biological functions of MAGE proteins

(2011) Yue Feng et al.   Protein & Cell

A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients

(2010) S. Roessler et al.   CANCER RESEARCH

Mage-A Cancer/Testis Antigens Inhibit p53 Function by Blocking Its Interaction with Chromatin

(2010) L. Marcar et al.   CANCER RESEARCH

An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma

(2010) George P. Kim et al.   INVESTIGATIONAL NEW DRUGS

aMAGEing New Players Enter the RING to Promote Ubiquitylation

(2010) Kristen C. Espantman et al.   MOLECULAR CELL

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

(2010) Jennifer M. Doyle et al.   MOLECULAR CELL

KAP1 Is Associated With Peritoneal Carcinomatosis in Gastric Cancer

(2009) Takeshi Yokoe et al.   ANNALS OF SURGICAL ONCOLOGY

Bortezomib suppresses focal adhesion kinase expression via interrupting nuclear factor-kappa B

(2009) Bor-Sheng Ko et al.   LIFE SCIENCES

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

(2009) X Liu et al.   ONCOGENE

Frequent expression of the novel cancer testis antigen MAGE-C2/CT-10 in hepatocellular carcinoma

(2008) Marc-Oliver Riener et al.   INTERNATIONAL JOURNAL OF CANCER