HBP1-Mediated Transcriptional Regulation of DNA Methyltransferase 1 and Its Impact on Cell Senescence

Twist-1 Induces Ezh2 Recruitment Regulating Histone Methylation along the Ink4A/Arf Locus in Mesenchymal Stem Cells

(2012) D. Cakouros et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

(2012) J. Song et al.   SCIENCE

Analysis of global DNA methylation by hydrophilic interaction ultra high-pressure liquid chromatography tandem mass spectrometry

(2011) Jun-jie Zhang et al.   ANALYTICAL BIOCHEMISTRY

All-trans retinoic acid induces cellular senescence by up-regulating levels of p16 and p21 via promoter hypomethylation

(2011) Joo Song Lim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Physical Association of HDAC1 and HDAC2 with p63 Mediates Transcriptional Repression and Tumor Maintenance in Squamous Cell Carcinoma

(2011) M. R. Ramsey et al.   CANCER RESEARCH

Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma

(2011) Michele Avissar-Whiting et al.   Epigenetics

SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

(2011) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

(2011) Zuping Zhang et al.   Molecular Cancer

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression

(2011) W. Wang et al.   NUCLEIC ACIDS RESEARCH

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

(2011) Max Felle et al.   NUCLEIC ACIDS RESEARCH

DNA Methyltransferase Controls Stem Cell Aging by Regulating BMI1 and EZH2 through MicroRNAs

(2011) Ah-Young So et al.   PLoS One

miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1

(2010) Hongling Li et al.   BREAST CANCER RESEARCH AND TREATMENT

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence

(2010) Agustin Chicas et al.   CANCER CELL

Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors

(2010) Flora Chik et al.   CARCINOGENESIS

BRCA1 affects global DNA methylation through regulation of DNMT1

(2010) Vivek Shukla et al.   CELL RESEARCH

Acetylation-dependent oncogenic activity of metastasis-associated protein 1 co-regulator

(2010) Kazufumi Ohshiro et al.   EMBO REPORTS

p35 Is Required for CDK5 Activation in Cellular Senescence

(2010) Daqin Mao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Regulation of HIC1 Target Genes by CtBP and NuRD, via an Acetylation/SUMOylation Switch, in Quiescent versus Proliferating Cells

(2010) C. Van Rechem et al.   MOLECULAR AND CELLULAR BIOLOGY

Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine

(2010) Seung-Gi Jin et al.   NUCLEIC ACIDS RESEARCH

Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence

(2010) H Li et al.   ONCOGENE

Macrophage migration inhibitory factor is a direct target of HBP1-mediated transcriptional repression that is overexpressed in prostate cancer

(2010) Y C Chen et al.   ONCOGENE

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Decreased DNA methyltransferase levels contribute to abnormal gene expression in “senescent” CD4+CD28− T cells

(2009) Ying Liu et al.   CLINICAL IMMUNOLOGY

Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes

(2009) YePeng Li et al.   EXPERIMENTAL GERONTOLOGY

Polycomb protein Ezh2 regulates pancreatic  -cell Ink4a/Arf expression and regeneration in diabetes mellitus

(2009) H. Chen et al.   GENES & DEVELOPMENT

The Tumor Suppressor Protein HBP1 Is a Novel c-Myc-binding Protein That Negatively Regulates c-Myc Transcriptional Activity

(2009) Julienne R. Escamilla-Powers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant DNA methylation status in human uterine leiomyoma

(2009) Y. Yamagata et al.   MOLECULAR HUMAN REPRODUCTION

5-Lipoxygenase and epigenetic DNA methylation in aging cultures of cerebellar granule cells

(2009) M. Imbesi et al.   NEUROSCIENCE

Immunolocalization of DNMT1 and DNMT3a in Salivary Gland Neoplasms

(2009) Carolina Cavaliéri Gomes et al.   PATHOBIOLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis

(2008) Xiaoyun Liao et al.   INTERNATIONAL JOURNAL OF CANCER

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS