Corni Fructus: a review of chemical constituents and pharmacological activities

Four new iridoid glucosides containing the furan ring from the fruit of Cornus officinalis

(2017) Jun He et al.   FITOTERAPIA

Combination of Morroniside and Diosgenin Prevents High Glucose-Induced Cardiomyocytes Apoptosis

(2017) Wen-Xia Pi et al.   MOLECULES

Antioxidant activities and oxidative stress inhibitory effects of ethanol extracts from Cornus officinalis on raw 264.7 cells

(2016) Kyung-A Hwang et al.   BMC Complementary and Alternative Medicine

Optimization for ultrasonic-microwave synergistic extraction of polysaccharides from Cornus officinalis and characterization of polysaccharides

(2016) Xiulian Yin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synergistic interaction of effective parts in Rehmanniae Radix and Cornus officinalis ameliorates renal injury in C57BL/KsJ-db/db diabetic mice: Involvement of suppression of AGEs/RAGE/SphK1 signaling pathway

(2016) Xing Lv et al.   JOURNAL OF ETHNOPHARMACOLOGY

Iridoid glycoside from Cornus officinalis ameliorated diabetes mellitus-induced testicular damage in male rats: Involvement of suppression of the AGEs/RAGE/p38 MAPK signaling pathway

(2016) Yuping Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Preventing the BDNF and NGF loss involved in the effects of cornel iridoid glycoside on attenuation of experimental autoimmune encephalomyelitis in mice

(2016) Zhao Qu et al.   NEUROLOGICAL RESEARCH

Inhibitory effects of Chinese nutritional herbs in isogenic breast carcinoma cells with modulated estrogen receptor function

(2016) Nitin Telang et al.   Oncology Letters

Patterns of Chinese medicine use in prescriptions for treating Alzheimer’s disease in Taiwan

(2016) Shun-Ku Lin et al.   Chinese Medicine

Identification of Chinese medicine syndromes in persistent insomnia associated with major depressive disorder: a latent tree analysis

(2016) Wing-Fai Yeung et al.   Chinese Medicine

Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach

(2015) Jihoon Nah et al.   MOLECULES AND CELLS

A new secoiridoid glycoside from the fruits ofCornus officinalis(Cornaceae)

(2015) Ji-Yeon Park et al.   NATURAL PRODUCT RESEARCH

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

The Hypoglycemic and Synergistic Effect of Loganin, Morroniside, and Ursolic Acid Isolated from the Fruits ofCornus officinalis

(2015) Kai He et al.   PHYTOTHERAPY RESEARCH

Fructus Corni extract-induced neuritogenesis in PC12 cells is associated with the suppression of stromal interaction molecule 1 expression and inhibition of Ca2+ influx

(2015) XUSHI WANG et al.   Experimental and Therapeutic Medicine

Selective Therapeutic Effect of Cornus officinalis Fruits on the Damage of Different Organs in STZ-Induced Diabetic Rats

(2014) Yunkyung Han et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Polyphenol isolated from Corni Fructus, 7-O-galloyl-d-sedoheptulose, modulates advanced glycation endproduct-related pathway in type 2 diabetic db/db mice

(2014) Chan Hum Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Bioactive compounds from Cornus officinalis fruits and their effects on diabetic nephropathy

(2014) Wei Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

Involvement of JAK/STAT signaling in the effect of cornel iridoid glycoside on experimental autoimmune encephalomyelitis amelioration in rats

(2014) Linlin Yin et al.   JOURNAL OF NEUROIMMUNOLOGY

Effect of 5-hydroxymethylfurfural derived from processed Cornus officinalis on the prevention of high glucose-induced oxidative stress in human umbilical vein endothelial cells and its mechanism

(2013) Gang Cao et al.   FOOD CHEMISTRY

Antiplatelet Activity of a Novel Formula Composed of Malic Acid, Succinic Acid and Citric Acid fromCornus officinalisFruit

(2013) Qi-Chun Zhang et al.   PHYTOTHERAPY RESEARCH

Chemical constituents from the fruits of Cornus officinalis

(2012) Xiao-Yu Xie et al.   BIOCHEMICAL SYSTEMATICS AND ECOLOGY

Protective effects of sweroside on human MG-63 cells and rat osteoblasts

(2012) Hui Sun et al.   FITOTERAPIA

Effects of Corni fructus on ovalbumin-induced airway inflammation and airway hyper-responsiveness in a mouse model of allergic asthma

(2012) Seung-Hyung Kim et al.   Journal of Inflammation-London

Rapid simultaneous identification and determination of the multiple compounds in crudeFructus Corniand its processed products by HPLC–MS/MS with multiple reaction monitoring mode

(2012) Hao Cai et al.   PHARMACEUTICAL BIOLOGY

The Effects of Corni Fructus Extract and Its Fractions Against α-Glucosidase Inhibitory Activities in Vitro and Sucrose Tolerance in Normal Rats

(2011) Chan Hum Park et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Cornuside Suppresses Lipopolysaccharide-Induced Inflammatory Mediators by Inhibiting Nuclear Factor-Kappa B Activation in RAW 264.7 Macrophages

(2011) Yun Ho Choi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Evaluation of the Potential Hypoglycemic and Beta-Cell Protective Constituents Isolated from Corni Fructus To Tackle Insulin-Dependent Diabetes Mellitus

(2011) Mei-Hsiang Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of loganin on experimental diabetic nephropathy

(2011) Wang-Lin Jiang et al.   PHYTOMEDICINE

Neuroprotective iridoid glycosides from Cornus officinalis fruits against glutamate-induced toxicity in HT22 hippocampal cells

(2011) Eun Ju Jeong et al.   PHYTOMEDICINE

Oleanolic Acid and Ursolic Acid Derived fromCornus officinalisSieb. et Zucc. Suppress Epidermal Growth Factor- and Phorbol Ester-induced MUC5AC Mucin Production and Gene Expression from Human Airway Epithelial Cells

(2011) Kyoungrai Cho et al.   PHYTOTHERAPY RESEARCH

Comparative Study for α-Glucosidase Inhibitory Effects of Total Iridoid Glycosides in the Crude Products and the Wine-processed Products from Cornus officinalis

(2011) Li-Hua HE   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Neuroprotective effect of morroniside on focal cerebral ischemia in rats

(2010) Wen Wang et al.   BRAIN RESEARCH BULLETIN

Isolation and structural characterization of a polysaccharide FCAP1 from the fruit of Cornus officinalis

(2010) Liyan Yang et al.   CARBOHYDRATE RESEARCH

Cornel iridoid glycoside improves memory ability and promotes neuronal survival in fimbria–fornix transected rats

(2010) Li-hong Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of 5-hydroxymethylfurfural derived from processed Fructus Corni on human hepatocyte LO2 injured by hydrogen peroxide and its mechanism

(2010) Xia Ding et al.   JOURNAL OF ETHNOPHARMACOLOGY

Investigation on the morphological protective effect of 5-hydroxymethylfurfural extracted from wine-processed Fructus corni on human L02 hepatocytes

(2010) Ming-Yan Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats

(2010) Min-You Qi et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Protective Effect of Ursolic Acid from Cornus officinalis on the Hydrogen Peroxide-Induced Damage of HEI-OC1 Auditory Cells

(2009) Hyeon-Hee Yu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

7-O-Galloyl-D-sedoheptulose Is a Novel Therapeutic Agent against Oxidative Stress and Advanced Glycation Endproducts in the Diabetic Kidney

(2009) Noriko Yamabe et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cornel iridoid glycoside promotes neurogenesis and angiogenesis and improves neurological function after focal cerebral ischemia in rats

(2009) R.-Q. Yao et al.   BRAIN RESEARCH BULLETIN

Morroniside protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide-induced cytotoxicity

(2009) Wen Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Fructus Corni suppresses hepatic gluconeogenesis related gene transcription, enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death

(2008) Chien-Chih Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY