Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment

Protection against Shiga Toxins

(2017) Simona Kavaliauskiene et al.   Toxins

Nanobodies as therapeutics: big opportunities for small antibodies

(2016) Sophie Steeland et al.   DRUG DISCOVERY TODAY

Development of camelid single chain antibodies against Shiga toxin type 2 (Stx2) with therapeutic potential against Hemolytic Uremic Syndrome (HUS)

(2016) Maria P. Mejías et al.   Scientific Reports

The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers

(2016) Sven O. Dahms et al.   Scientific Reports

The epidemiology, microbiology and clinical impact of Shiga toxin-producing Escherichia coli in England, 2009–2012

(2015) L. BYRNE et al.   EPIDEMIOLOGY AND INFECTION

Increasing the potency of neutralizing single-domain antibodies by functionalization with a CD11b/CD18 binding domain

(2015) Martin A Rossotti et al.   mAbs

A camelid antibody candidate for development of a therapeutic agent against Hemiscorpius lepturus envenomation

(2014) Najmeh Yardehnavi et al.   FASEB JOURNAL

The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain

(2014) Alvin W. H. Lo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ThePDB_REDOserver for macromolecular structure model optimization

(2014) Robbie P. Joosten et al.   IUCrJ

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2

(2013) Jacqueline M. Tremblay et al.   INFECTION AND IMMUNITY

Nanobodies as novel agents for disease diagnosis and therapy

(2013) Christina G. Siontorou   International Journal of Nanomedicine

Advances in pathogenesis and therapy of hemolytic uremic syndrome caused by shiga toxin-2

(2013) Cristina Ibarra et al.   IUBMB LIFE

Immunization with a Chimera Consisting of the B Subunit of Shiga Toxin Type 2 and Brucella Lumazine Synthase Confers Total Protection against Shiga Toxins in Mice

(2013) M. P. Mejias et al.   JOURNAL OF IMMUNOLOGY

Nanobodies and their potential applications

(2013) Gholamreza Hassanzadeh-Ghassabeh et al.   Nanomedicine

Long-term outcomes of Shiga toxin hemolytic uremic syndrome

(2013) Joann M. Spinale et al.   PEDIATRIC NEPHROLOGY

Ribosome-inactivating proteins

(2013) Matthew J Walsh et al.   Virulence

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER

(2012) Oliver S. Smart et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Need for Long-term Follow-up in Enterohemorrhagic Escherichia coli–Associated Hemolytic Uremic Syndrome Due to Late-Emerging Sequelae

(2012) Alejandra Rosales et al.   CLINICAL INFECTIOUS DISEASES

The enemy within us: lessons from the 2011 EuropeanEscherichia coliO104:H4 outbreak

(2012) Helge Karch et al.   EMBO Molecular Medicine

Nanobody®-based chromatin immunoprecipitation/micro-array analysis for genome-wide identification of transcription factor DNA binding sites

(2012) Trong Nguyen-Duc et al.   NUCLEIC ACIDS RESEARCH

Shiga toxins

(2012) Jonas Bergan et al.   TOXICON

Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli

(2012) Susanne Hauswaldt et al.   Current Infectious Disease Reports

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Protection of Piglets against Edema Disease by Maternal Immunization with Stx2e Toxoid

(2011) Thi Kim Nguyen Oanh et al.   INFECTION AND IMMUNITY

Shiga Toxin Subtypes Display Dramatic Differences in Potency

(2011) Cynthia A. Fuller et al.   INFECTION AND IMMUNITY

Epidemic Profile of Shiga-Toxin–ProducingEscherichia coliO104:H4 Outbreak in Germany

(2011) Christina Frank et al.   NEW ENGLAND JOURNAL OF MEDICINE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A bispecific nanobody to provide full protection against lethal scorpion envenoming

(2010) Issam Hmila et al.   FASEB JOURNAL

Escherichia coli O157

(2010) Hugh Pennington   LANCET

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Hemolytic uremic syndrome: pathogenesis and update of interventions

(2009) Marina S Palermo et al.   Expert Review of Anti-Infective Therapy

The Economics of Enteric Infections: Human Foodborne Disease Costs

(2009) Jean C. Buzby et al.   GASTROENTEROLOGY

Shiga toxins — from cell biology to biomedical applications

(2009) Ludger Johannes et al.   NATURE REVIEWS MICROBIOLOGY