Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons

Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1

(2017) Rajeshwer S. Sankhala et al.   Nature Communications

Viral gene products actively promote latent infection by epigenetic silencing mechanisms

(2017) David M Knipe et al.   Current Opinion in Virology

A Therapeutic Antiviral Antibody Inhibits the Anterograde Directed Neuron-to-Cell Spread of Herpes Simplex Virus and Protects against Ocular Disease

(2017) Dirk Bauer et al.   Frontiers in Microbiology

Importin α: a key molecule in nuclear transport and non-transport functions

(2016) Yoichi Miyamoto et al.   JOURNAL OF BIOCHEMISTRY

Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits

(2016) Rajeshwer S. Sankhala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Biology and Regulation of Protein Import into the Nucleus

(2016) Mary Christie et al.   JOURNAL OF MOLECULAR BIOLOGY

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1

(2016) James R. Brown et al.   JOURNAL OF VIROLOGY

Conserved Tryptophan Motifs in the Large Tegument Protein pUL36 Are Required for Efficient Secondary Envelopment of Herpes Simplex Virus Capsids

(2016) Lyudmila Ivanova et al.   JOURNAL OF VIROLOGY

VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability

(2016) Toni M. Schwarz et al.   JOURNAL OF VIROLOGY

Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles

(2016) H. Broder Schmidt et al.   TRENDS IN BIOCHEMICAL SCIENCES

Herpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is Key

(2016) Henri Gruffat et al.   Frontiers in Microbiology

Diversification of importin-α isoforms in cellular trafficking and disease states

(2015) Ruth A. Pumroy et al.   BIOCHEMICAL JOURNAL

Microtubule plus end–associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells

(2015) Vladimir Jovasevic et al.   JOURNAL OF CELL BIOLOGY

The nuclear pore complex - structure and function at a glance

(2015) G. Kabachinski et al.   JOURNAL OF CELL SCIENCE

Herpesvirus gB: A Finely Tuned Fusion Machine

(2015) Rebecca Cooper et al.   Viruses-Basel

Selective Recruitment of Nuclear Factors to Productively Replicating Herpes Simplex Virus Genomes

(2015) Jill A. Dembowski et al.   PLoS Pathogens

Prevention of Herpes Simplex Virus Induced Stromal Keratitis by a Glycoprotein B-Specific Monoclonal Antibody

(2015) Adalbert Krawczyk et al.   PLoS One

Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

(2014) Wei Xu et al.   Cell Host & Microbe

The α-importome of mammalian germ cell maturation provides novel insights for importin biology

(2014) Arash Arjomand et al.   FASEB JOURNAL

Contribution of Direct and Cross-Presentation to CTL Immunity against Herpes Simplex Virus 1

(2014) A. C. Jirmo et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Virus Internalization into Epithelial Cells Requires Na+/H+ Exchangers and p21-Activated Kinases but neither Clathrin- nor Caveolin-Mediated Endocytosis

(2014) D. Devadas et al.   JOURNAL OF VIROLOGY

Functional Analysis of Nuclear Localization Signals in VP1-2 Homologues from All Herpesvirus Subfamilies

(2014) T. Hennig et al.   JOURNAL OF VIROLOGY

Identification of Importin α 7 Specific Transport Cargoes Using a Proteomic Screening Approach

(2014) Stefanie Hügel et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural basis for nuclear import of splicing factors by human Transportin 3

(2014) G. N. Maertens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

(2014) A. Franceschini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of Viral Capsids to Nuclear Pores in a Cell-Free Reconstitution System

(2014) Fenja Anderson et al.   TRAFFIC

Biological Significance of the Importin-β Family-Dependent Nucleocytoplasmic Transport Pathways

(2014) Makoto Kimura et al.   TRAFFIC

An Inquiry into the Molecular Basis of HSV Latency and Reactivation

(2013) Bernard Roizman et al.   Annual Review of Microbiology

Importin Alpha Subtypes Determine Differential Transcription Factor Localization in Embryonic Stem Cells Maintenance

(2013) Noriko Yasuhara et al.   DEVELOPMENTAL CELL

Chromatin Dynamics during Lytic Infection with Herpes Simplex Virus 1

(2013) Kristen Conn et al.   Viruses-Basel

The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection

(2013) Jodi Vogel et al.   Viruses-Basel

Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins

(2013) Gualtiero Alvisi et al.   Viruses-Basel

A Systematic Analysis of Host Factors Reveals a Med23-Interferon-λ Regulatory Axis against Herpes Simplex Virus Type 1 Replication

(2013) Samantha J. Griffiths et al.   PLoS Pathogens

Cytosolic herpes simplex virus capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment

(2012) Malte Sandbaumhüter et al.   CELLULAR MICROBIOLOGY

Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ

(2012) Jieliang Chen et al.   HEPATOLOGY

Regulation of alphaherpesvirus infections by the ICP0 family of proteins

(2012) C. Boutell et al.   JOURNAL OF GENERAL VIROLOGY

Identification of a novel NLS of herpes simplex virus type 1 (HSV-1) VP19C and its nuclear localization is required for efficient production of HSV-1

(2012) Y. Li et al.   JOURNAL OF GENERAL VIROLOGY

A Nuclear Localization Signal in Herpesvirus Protein VP1-2 Is Essential for Infection via Capsid Routing to the Nuclear Pore

(2012) F. Abaitua et al.   JOURNAL OF VIROLOGY

The C Terminus of the Large Tegument Protein pUL36 Contains Multiple Capsid Binding Sites That Function Differently during Assembly and Cell Entry of Herpes Simplex Virus

(2012) J. Schipke et al.   JOURNAL OF VIROLOGY

Single-cell analysis of population context advances RNAi screening at multiple levels

(2012) Berend Snijder et al.   Molecular Systems Biology

Improper Tagging of the Non-Essential Small Capsid Protein VP26 Impairs Nuclear Capsid Egress of Herpes Simplex Virus

(2012) Claus-Henning Nagel et al.   PLoS One

Active maintenance of nuclear actin by importin 9 supports transcription

(2012) J. Dopie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes Simplex Viruses: Mechanisms of DNA Replication

(2012) S. K. Weller et al.   Cold Spring Harbor Perspectives in Biology

The many roles of the highly interactive HSV protein ICP27, a key regulator of infection

(2011) Rozanne M Sandri-Goldin   Future Microbiology

Replication and Recombination of Herpes Simplex Virus DNA

(2011) Isabella Muylaert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncoupling Uncoating of Herpes Simplex Virus Genomes from Their Nuclear Import and Gene Expression

(2011) K. Rode et al.   JOURNAL OF VIROLOGY

Importin α7 Is Essential for Zygotic Genome Activation and Early Mouse Development

(2011) Franziska Rother et al.   PLoS One

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

(2011) Gülsah Gabriel et al.   Nature Communications

Molecular Basis for the Recognition of Phosphorylated STAT1 by Importin α5

(2010) Jonathan Nardozzi et al.   JOURNAL OF MOLECULAR BIOLOGY

CD317/Tetherin Is Enriched in the HIV-1 Envelope and Downregulated from the Plasma Membrane upon Virus Infection

(2010) A. Habermann et al.   JOURNAL OF VIROLOGY

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

(2009) Lasse Weinmann et al.   CELL

Evolution of the Metazoan-Specific Importin α Gene Family

(2009) D. Adam Mason et al.   JOURNAL OF MOLECULAR EVOLUTION

The role of the nuclear transport system in cell differentiation

(2009) Noriko Yasuhara et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Nuclear transport factors in neuronal function

(2009) Rotem Ben-Tov Perry et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Nuclear Import of HSV-1 DNA Polymerase Processivity Factor UL42 Is Mediated by a C-Terminally Located Bipartite Nuclear Localization Signal†

(2008) Gualtiero Alvisi et al.   BIOCHEMISTRY

Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α

(2008) Shunichi Kosugi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of karyopherin-alpha 2 as an Oct4 associated protein

(2008) Xiangqun Li et al.   Journal of Genetics and Genomics

Differing Roles of Inner Tegument Proteins pUL36 and pUL37 during Entry of Herpes Simplex Virus Type 1

(2008) A. P. E. Roberts et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment

(2008) A. M. Copeland et al.   JOURNAL OF VIROLOGY

Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons

(2008) K.-O. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA