Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1

Diversification of importin-α isoforms in cellular trafficking and disease states

(2015) Ruth A. Pumroy et al.   BIOCHEMICAL JOURNAL

Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

(2015) Sigrid Milles et al.   CELL

Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins

(2015) Annemarie Kralt et al.   MOLECULAR BIOLOGY OF THE CELL

Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2

(2015) Ravi K. Lokareddy et al.   STRUCTURE

Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin α Isoforms 3 and 7

(2015) Ruth A. Pumroy et al.   STRUCTURE

Upgrade of MacCHESS facility for X-ray scattering of biological macromolecules in solution

(2015) Alvin Samuel Acerbo et al.   JOURNAL OF SYNCHROTRON RADIATION

Quantitative method for the assignment of hinge and shear mechanism in protein domain movements

(2014) Daniel Taylor et al.   BIOINFORMATICS

Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

(2014) Wei Xu et al.   Cell Host & Microbe

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

(2014) Stefan Reich et al.   NATURE

Flexible torsion-angle noncrystallographic symmetry restraints for improved macromolecular structure refinement

(2014) Jeffrey J. Headd et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Importin Alpha Subtypes Determine Differential Transcription Factor Localization in Embryonic Stem Cells Maintenance

(2013) Noriko Yasuhara et al.   DEVELOPMENTAL CELL

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-α

(2012) Mary Marfori et al.   TRAFFIC

Mapping the Phosphoproteome of Influenza A and B Viruses by Mass Spectrometry

(2012) Edward C. Hutchinson et al.   PLoS Pathogens

A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin α1

(2011) Kaylen Lott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

(2011) Gülsah Gabriel et al.   Nature Communications

The importin β binding domain as a master regulator of nucleocytoplasmic transport

(2010) Kaylen Lott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular basis for specificity of nuclear import and prediction of nuclear localization

(2010) Mary Marfori et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells

(2010) Ekarat Hitakomate et al.   BMC CELL BIOLOGY

Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors

(2010) Joshua B Kelley et al.   BMC CELL BIOLOGY

Novel Binding of the Mitotic Regulator TPX2 (Target Protein forXenopusKinesin-like Protein 2) to Importin-α

(2010) Astrid Giesecke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for the Recognition of Phosphorylated STAT1 by Importin α5

(2010) Jonathan Nardozzi et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural characterization of proteins and complexes using small-angle X-ray solution scattering

(2010) Haydyn D.T. Mertens et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of RCC1 chromatin factor bound to the nucleosome core particle

(2010) Ravindra D. Makde et al.   NATURE

NRMT is an α-N-methyltransferase that methylates RCC1 and retinoblastoma protein

(2010) Christine E. Schaner Tooley et al.   NATURE

FoXS: a web server for rapid computation and fitting of SAXS profiles

(2010) D. Schneidman-Duhovny et al.   NUCLEIC ACIDS RESEARCH

Quantitative Structural Analysis of Importin-β Flexibility: Paradigm for Solenoid Protein Structures

(2010) Jade K. Forwood et al.   STRUCTURE

BioXTAS RAW, a software program for high-throughput automated small-angle X-ray scattering data reduction and preliminary analysis

(2009) S. S. Nielsen et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

DAMMIF, a program for rapidab-initioshape determination in small-angle scattering

(2009) Daniel Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Evolution of the Metazoan-Specific Importin α Gene Family

(2009) D. Adam Mason et al.   JOURNAL OF MOLECULAR EVOLUTION

The molecular basis for the regulation of the cap-binding complex by the importins

(2009) Sandra M G Dias et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The RCC1 superfamily: From genes, to function, to disease

(2008) Ouadah Hadjebi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

NF-κB p52, RelB and c-Rel are transported into the nucleus via a subset of importin α molecules

(2008) Riku Fagerlund et al.   CELLULAR SIGNALLING

Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α

(2008) Shunichi Kosugi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1

(2008) Yi Hao et al.   JOURNAL OF CELL BIOLOGY

The RanGTP gradient - a GPS for the mitotic spindle

(2008) P. Kalab et al.   JOURNAL OF CELL SCIENCE