Herpes Simplex Virus Internalization into Epithelial Cells Requires Na+/H+ Exchangers and p21-Activated Kinases but neither Clathrin- nor Caveolin-Mediated Endocytosis

Virus entry at a glance

(2013) Y. Yamauchi et al.   JOURNAL OF CELL SCIENCE

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors

(2013) R. J. Park et al.   JOURNAL OF CELL SCIENCE

Alphaherpesviral US3 Kinase Induces Cofilin Dephosphorylation To Reorganize the Actin Cytoskeleton

(2013) T. Jacob et al.   JOURNAL OF VIROLOGY

Echovirus 1 Entry into Polarized Caco-2 Cells Depends on Dynamin, Cholesterol, and Cellular Factors Associated with Macropinocytosis

(2013) S. E. Krieger et al.   JOURNAL OF VIROLOGY

The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K Is Required for Virion Entry via the Paired Immunoglobulin-Like Type-2 Receptor Alpha

(2013) S. Chowdhury et al.   JOURNAL OF VIROLOGY

Type I Interferon and NF- B Activation Elicited by Herpes Simplex Virus gH/gL via  v 3 Integrin in Epithelial and Neuronal Cell Lines

(2013) T. Gianni et al.   JOURNAL OF VIROLOGY

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin-Propelled Invasive Membrane Protrusions Promote Fusogenic Protein Engagement During Cell-Cell Fusion

(2013) K. Shilagardi et al.   SCIENCE

Virus interactions with endocytic pathways in macrophages and dendritic cells

(2013) Jason Mercer et al.   TRENDS IN MICROBIOLOGY

αvβ6- and αvβ8-Integrins Serve As Interchangeable Receptors for HSV gH/gL to Promote Endocytosis and Activation of Membrane Fusion

(2013) Tatiana Gianni et al.   PLoS Pathogens

Host Cell Entry of Respiratory Syncytial Virus Involves Macropinocytosis Followed by Proteolytic Activation of the F Protein

(2013) Magdalena Anna Krzyzaniak et al.   PLoS Pathogens

Roles for Actin Assembly in Endocytosis

(2012) Olivia L. Mooren et al.   Annual Review of Biochemistry

Herpesvirus Transport to the Nervous System and Back Again

(2012) Gregory Smith   Annual Review of Microbiology

Cytosolic herpes simplex virus capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment

(2012) Malte Sandbaumhüter et al.   CELLULAR MICROBIOLOGY

Gulping rather than sipping: macropinocytosis as a way of virus entry

(2012) Jason Mercer et al.   CURRENT OPINION IN MICROBIOLOGY

Ultrastructural Visualization of Individual Tegument Protein Dissociation during Entry of Herpes Simplex Virus 1 into Human and Rat Dorsal Root Ganglion Neurons

(2012) A. Aggarwal et al.   JOURNAL OF VIROLOGY

The C Terminus of the Large Tegument Protein pUL36 Contains Multiple Capsid Binding Sites That Function Differently during Assembly and Cell Entry of Herpes Simplex Virus

(2012) J. Schipke et al.   JOURNAL OF VIROLOGY

Single-cell analysis of population context advances RNAi screening at multiple levels

(2012) Berend Snijder et al.   Molecular Systems Biology

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

(2012) Callista B. Harper et al.   TRENDS IN CELL BIOLOGY

Herpes Virus Fusion and Entry: A Story with Many Characters

(2012) Roselyn J. Eisenberg et al.   Viruses-Basel

Viral and cellular contributions to herpes simplex virus entry into the cell

(2012) Gabriella Campadelli-Fiume et al.   Current Opinion in Virology

Entry of Human Papillomavirus Type 16 by Actin-Dependent, Clathrin- and Lipid Raft-Independent Endocytosis

(2012) Mario Schelhaas et al.   PLoS Pathogens

Decoupling of the Catalytic and Transport Activities of Complex I fromRhodothermus marinusby Sodium/Proton Antiporter Inhibitor

(2011) Ana P. Batista et al.   ACS Chemical Biology

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

(2011) Lisa von Kleist et al.   CELL

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture

(2011) Florian Ingo Schmidt et al.   EMBO JOURNAL

Macropinocytosis: an endocytic pathway for internalising large gulps

(2011) Jet Phey Lim et al.   IMMUNOLOGY AND CELL BIOLOGY

Single cell detection of latent cytomegalovirus reactivation in host tissue

(2011) A. Marquardt et al.   JOURNAL OF GENERAL VIROLOGY

Ebola Virus Enters Host Cells by Macropinocytosis and Clathrin-Mediated Endocytosis

(2011) Paulina Aleksandrowicz et al.   JOURNAL OF INFECTIOUS DISEASES

 V 3-Integrin Relocalizes nectin1 and Routes Herpes Simplex Virus to Lipid Rafts

(2011) T. Gianni et al.   JOURNAL OF VIROLOGY

Low-pH-Dependent Changes in the Conformation and Oligomeric State of the Prefusion Form of Herpes Simplex Virus Glycoprotein B Are Separable from Fusion Activity

(2011) S. J. Dollery et al.   JOURNAL OF VIROLOGY

Subversion of the actin cytoskeleton during viral infection

(2011) Matthew P. Taylor et al.   NATURE REVIEWS MICROBIOLOGY

Fusing structure and function: a structural view of the herpesvirus entry machinery

(2011) Sarah A. Connolly et al.   NATURE REVIEWS MICROBIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Entry Pathways of Herpes Simplex Virus Type 1 into Human Keratinocytes Are Dynamin- and Cholesterol-Dependent

(2011) Elena Rahn et al.   PLoS One

At the Crossroads of Chemistry and Cell Biology: Inhibiting Membrane Traffic by Small Molecules

(2011) Lisa Kleist et al.   TRAFFIC

Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway

(2011) Erik de Vries et al.   PLoS Pathogens

Virus Entry by Endocytosis

(2010) Jason Mercer et al.   Annual Review of Biochemistry

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry

(2010) V. Tiwari et al.   JOURNAL OF GENERAL VIROLOGY

Macropinocytotic Uptake and Infection of Human Epithelial Cells with Species B2 Adenovirus Type 35

(2010) S. Kalin et al.   JOURNAL OF VIROLOGY

Structural Basis of Local, pH-Dependent Conformational Changes in Glycoprotein B from Herpes Simplex Virus Type 1

(2010) S. D. Stampfer et al.   JOURNAL OF VIROLOGY

 V 3-integrin routes herpes simplex virus to an entry pathway dependent on cholesterol-rich lipid rafts and dynamin2

(2010) T. Gianni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Entry of Ebola Virus Involves Uptake by a Macropinocytosis-Like Mechanism and Subsequent Trafficking through Early and Late Endosomes

(2010) Mohammad F. Saeed et al.   PLoS Pathogens

The Length of Vesicular Stomatitis Virus Particles Dictates a Need for Actin Assembly during Clathrin-Dependent Endocytosis

(2010) David K. Cureton et al.   PLoS Pathogens

Antiviral therapy for herpesvirus central nervous system infections: Neonatal herpes simplex virus infection, herpes simplex encephalitis, and congenital cytomegalovirus infection

(2009) Scott H. James et al.   ANTIVIRAL RESEARCH

A role for heparan sulfate in viral surfing

(2009) Myung-Jin Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Entry of Herpes Simplex Virus 1 and Other Alphaherpesviruses via the Paired Immunoglobulin-Like Type 2 Receptor  

(2009) J. Arii et al.   JOURNAL OF VIROLOGY

Virus entry by macropinocytosis

(2009) Jason Mercer et al.   NATURE CELL BIOLOGY

Defining Macropinocytosis

(2009) Markus C. Kerr et al.   TRAFFIC

Entry of herpesviruses into mammalian cells

(2008) E. E. Heldwein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase

(2008) Sean W. Deacon et al.   CHEMISTRY & BIOLOGY

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS

(2008) Prisca Liberali et al.   EMBO JOURNAL

Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3

(2008) Beat Amstutz et al.   EMBO JOURNAL

Rapid quantitative PCR assays for the simultaneous detection of herpes simplex virus, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and human herpesvirus 6 DNA in blood and other clinical specimens

(2008) I. Engelmann et al.   JOURNAL OF MEDICAL VIROLOGY

Shaping cups into phagosomes and macropinosomes

(2008) Joel A. Swanson   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clathrin and LRP-1-Independent Constitutive Endocytosis and Recycling of uPAR

(2008) Katia Cortese et al.   PLoS One

Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry

(2008) U. E. Maurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinia Virus Uses Macropinocytosis and Apoptotic Mimicry to Enter Host Cells

(2008) J. Mercer et al.   SCIENCE