Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

(2017) Erika Pellegrini et al.   STRUCTURE

Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression

(2016) Philipp Olias et al.   Cell Host & Microbe

Toxoplasma gondiiTgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses

(2016) Gabrielle Gay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Novel Secreted Protein, MYR1, Is Central to Toxoplasma ’s Manipulation of Host Cells

(2016) Magdalena Franco et al.   mBio

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole

(2015) Daniel A. Gold et al.   Cell Host & Microbe

The aspartyl protease TgASP5 mediates the export of theToxoplasmaGRA16 and GRA24 effectors into host cells

(2015) Aurélie Curt-Varesano et al.   CELLULAR MICROBIOLOGY

Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface

(2015) Pierre-Mehdi Hammoudi et al.   PLoS Pathogens

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell

(2015) Michael J Coffey et al.   eLife

The Toxoplasma Pseudokinase ROP5 Forms Complexes with ROP18 and ROP17 Kinases that Synergize to Control Acute Virulence in Mice

(2014) Ronald D. Etheridge et al.   Cell Host & Microbe

Infection by Toxoplasma gondii Specifically Induces Host c-Myc and the Genes This Pivotal Transcription Factor Regulates

(2014) Magdalena Franco et al.   EUKARYOTIC CELL

Selective and strain-specific NFAT4 activation by theToxoplasma gondiipolymorphic dense granule protein GRA6

(2014) Ji Su Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PTEX is an essential nexus for protein export in malaria parasites

(2014) Brendan Elsworth et al.   NATURE

PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes

(2014) Josh R. Beck et al.   NATURE

Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

(2014) B. Shen et al.   mBio

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

(2014) Lena Pernas et al.   PLOS BIOLOGY

Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression

(2013) Alexandre Bougdour et al.   Cell Host & Microbe

Poison Domains Block Transit of Translocated Substrates via the Legionella pneumophila Icm/Dot System

(2013) Whitney M. Amyot et al.   INFECTION AND IMMUNITY

AToxoplasmadense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

(2013) Laurence Braun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Nucleotide Sugar Transporter Involved in Glycosylation of the Toxoplasma Tissue Cyst Wall Is Required for Efficient Persistence of Bradyzoites

(2013) Carolina E. Caffaro et al.   PLoS Pathogens

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity

(2012) S. Minot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18

(2012) Michael S. Behnke et al.   PLoS Pathogens

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Efficient Gene Replacements inToxoplasma gondiiStrains Deficient for Nonhomologous End Joining

(2009) Barbara A. Fox et al.   EUKARYOTIC CELL

A newly discovered protein export machine in malaria parasites

(2009) Tania F. de Koning-Ward et al.   NATURE

The Gamma Interferon (IFN- )-Inducible GTP-Binding Protein IGTP Is Necessary for Toxoplasma Vacuolar Disruption and Induces Parasite Egression in IFN- -Stimulated Astrocytes

(2008) T. Melzer et al.   INFECTION AND IMMUNITY

The Toxoplasma gondii Dense Granule Protein GRA7 Is Phosphorylated upon Invasion and Forms an Unexpected Association with the Rhoptry Proteins ROP2 and ROP4

(2008) J. D. Dunn et al.   INFECTION AND IMMUNITY

Global Analysis of Gel Mobility of Proteins and Its Use in Target Identification

(2008) Atsuko Shirai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein unfolding is an essential requirement for transport across the parasitophorous vacuolar membrane ofPlasmodium falciparum

(2008) Nina Gehde et al.   MOLECULAR MICROBIOLOGY