Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

(2017) John D. Chan et al.   Nature Communications

Protein kinase A signalling in Schistosoma mansoni cercariae and schistosomules

(2016) Natasha L. Hirst et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Identification and profiling of microRNAs in two developmental stages of the model cestode parasite Mesocestoides corti

(2016) Tatiana Basika et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

(2016) A. J. Venkatakrishnan et al.   NATURE

A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

(2016) John D. Chan et al.   PLoS Pathogens

Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist

(2016) John D. Chan et al.   International Journal for Parasitology-Drugs and Drug Resistance

Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist

(2016) John D. Chan et al.   International Journal for Parasitology-Drugs and Drug Resistance

Chemoproteomic Approach to Explore the Target Profile of GPCR ligands: Application to 5-HT1A and 5-HT6 Receptors

(2015) Ana M. Gamo et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Structure and function of serotonin G protein-coupled receptors

(2015) John D. McCorvy et al.   PHARMACOLOGY & THERAPEUTICS

Threat of alveolar echinococcosis to public health – a challenge for Europe

(2015) Bruno Gottstein et al.   TRENDS IN PARASITOLOGY

Ergot Alkaloids (Re)generate New Leads as Antiparasitics

(2015) John D. Chan et al.   PLoS Neglected Tropical Diseases

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Serotonin Signaling in Schistosoma mansoni: A Serotonin–Activated G Protein-Coupled Receptor Controls Parasite Movement

(2014) Nicholas Patocka et al.   PLoS Pathogens

Near Full-Length Genome Identification of a Novel HIV Type 1 B′/C Recombinant Isolate JL100091 in Jilin, China

(2013) Chuanyi Ning et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)

(2013) Brian Kobilka   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The nervous and prenervous roles of serotonin in Echinococcus spp.

(2013) F. Camicia et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The genomes of four tapeworm species reveal adaptations to parasitism

(2013) Isheng J. Tsai et al.   NATURE

The genome of the hydatid tapeworm Echinococcus granulosus

(2013) Huajun Zheng et al.   NATURE GENETICS

Structural Basis for Molecular Recognition at Serotonin Receptors

(2013) C. Wang et al.   SCIENCE

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Serotonin and Synaptic Transmission at Invertebrate Neuromuscular Junctions

(2012) Wen-Hui Wu et al.   Experimental Neurobiology

Identification of Echinococcus granulosus microRNAs and their expression in different life cycle stages and parasite genotypes

(2011) M. Cucher et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective

(2010) Nicolas Guex et al.   ELECTROPHORESIS

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Phenotypic and genotypic characterisation of benzimidazole susceptible and resistant isolates of Haemonchus contortus

(2010) Patrícia Čudeková et al.   VETERINARY PARASITOLOGY

Development of Fluorescent Ligands for the Human 5-HT1A Receptor

(2010) Dulce Alonso et al.   ACS Medicinal Chemistry Letters

Treatment Response of Cystic Echinococcosis to Benzimidazoles: A Systematic Review

(2009) Marija Stojkovic et al.   PLoS Neglected Tropical Diseases

Serotonin Receptors

(2008) David E. Nichols et al.   CHEMICAL REVIEWS

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Agonist-selective mechanisms of GPCR desensitization

(2007) E Kelly et al.   BRITISH JOURNAL OF PHARMACOLOGY