A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

Forskolin-free cAMP assay for Gi-coupled receptors

(2015) Julie Gilissen et al.   BIOCHEMICAL PHARMACOLOGY

A constitutively active G protein-coupled acetylcholine receptor regulates motility of larval Schistosoma mansoni

(2015) Kevin MacDonald et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Ergot Alkaloids (Re)generate New Leads as Antiparasitics

(2015) John D. Chan et al.   PLoS Neglected Tropical Diseases

Schistosoma mansoni Egg, Adult Male and Female Comparative Gene Expression Analysis and Identification of Novel Genes by RNA-Seq

(2015) Letícia Anderson et al.   PLoS Neglected Tropical Diseases

The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer)

(2014) P. Olliaro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Human schistosomiasis

(2014) Daniel G Colley et al.   LANCET

Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics

(2014) Tulio D L Campos et al.   Parasites & Vectors

Serotonin Signaling in Schistosoma mansoni: A Serotonin–Activated G Protein-Coupled Receptor Controls Parasite Movement

(2014) Nicholas Patocka et al.   PLoS Pathogens

‘Death and Axes’: Unexpected Ca2+ Entry Phenologs Predict New Anti-schistosomal Agents

(2014) John D. Chan et al.   PLoS Pathogens

New approaches for understanding mechanisms of drug resistance in schistosomes

(2013) ROBERT M. GREENBERG   PARASITOLOGY

Muscle Cells Provide Instructions for Planarian Regeneration

(2013) Jessica N. Witchley et al.   Cell Reports

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction

(2012) Jia Bei Wang et al.   Future Medicinal Chemistry

Transcriptional analysis of Schistosoma mansoni treated with praziquantel in vitro

(2012) Jarrett Hines-Kay et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The functional role of a serotonin transporter in Schistosoma mansoni elucidated through immunolocalization and RNA interference (RNAi)

(2012) Nicholas Patocka et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Ca2+ channels and praziquantel: A view from the free world

(2012) John D. Chan et al.   PARASITOLOGY INTERNATIONAL

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

(2012) Wei Wang et al.   PARASITOLOGY RESEARCH

A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni

(2012) Anna V. Protasio et al.   PLoS Neglected Tropical Diseases

A Novel G Protein-Coupled Receptor of Schistosoma mansoni (SmGPR-3) Is Activated by Dopamine and Is Widely Expressed in the Nervous System

(2012) Fouad El-Shehabi et al.   PLoS Neglected Tropical Diseases

A Luminescent Biosensor with Increased Dynamic Range for Intracellular cAMP

(2011) Brock F. Binkowski et al.   ACS Chemical Biology

The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea

(2011) Mostafa Zamanian et al.   BMC GENOMICS

Opposing Roles of Voltage-Gated Ca2+ Channels in Neuronal Control of Regenerative Patterning

(2011) D. Zhang et al.   JOURNAL OF NEUROSCIENCE

Utility of Repeated Praziquantel Dosing in the Treatment of Schistosomiasis in High-Risk Communities in Africa: A Systematic Review

(2011) Charles H. King et al.   PLoS Neglected Tropical Diseases

Risperidone-Induced Inactivation and Clozapine-Induced Reactivation of Rat Cortical Astrocyte 5-Hydroxytryptamine7 Receptors: Evidence for In Situ G Protein-Coupled Receptor Homodimer Protomer Cross-Talk

(2010) C. Smith et al.   MOLECULAR PHARMACOLOGY

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

A Novel Biological Activity of Praziquantel Requiring Voltage-Operated Ca2+ Channel β Subunits: Subversion of Flatworm Regenerative Polarity

(2009) Taisaku Nogi et al.   PLoS Neglected Tropical Diseases

Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening

(2009) Maha-Hamadien Abdulla et al.   PLoS Neglected Tropical Diseases

Novel Genetically Encoded Biosensors Using Firefly Luciferase

(2008) Frank Fan et al.   ACS Chemical Biology

Towards an understanding of the mechanism of action of praziquantel

(2008) Anthony D. Aragon et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Pharmacological Analysis of the Novel, Rapid, and Potent Inactivation of the Human 5-Hydroxytryptamine7 Receptor by Risperidone, 9-OH-Risperidone, and Other Inactivating Antagonists

(2008) J. A. Knight et al.   MOLECULAR PHARMACOLOGY