Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin

(2017) Fan Yang et al.   Protein & Cell

Brown adipose tissue is involved in diet-induced thermogenesis and whole-body fat utilization in healthy humans

(2016) M Hibi et al.   INTERNATIONAL JOURNAL OF OBESITY

60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSH

(2016) Erica J P Anderson et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH

(2016) Henning Fenselau et al.   NATURE NEUROSCIENCE

Single-Cell Gene Expression Analysis of Cholinergic Neurons in the Arcuate Nucleus of the Hypothalamus

(2016) Jae Hoon Jeong et al.   PLoS One

Conditional Expression ofPomcin theLepr-Positive Subpopulation of POMC Neurons Is Sufficient for Normal Energy Homeostasis and Metabolism

(2015) Daniel D. Lam et al.   ENDOCRINOLOGY

Hypothalamic POMC neurons promote cannabinoid-induced feeding

(2015) Marco Koch et al.   NATURE

Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel

(2015) Fan Yang et al.   Nature Chemical Biology

TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response

(2015) Adrian T. Billeter et al.   SURGERY

Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons

(2015) Dong Kun Lee et al.   Nature Communications

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

(2015) Fredrick E Henry et al.   eLife

Capsaicin increases sensation of fullness in energy balance, and decreases desire to eat after dinner in negative energy balance☆

(2014) Pilou L.H.R. Janssens et al.   APPETITE

Hypothalamic Temperature of Rats Subjected to Treadmill Running in a Cold Environment

(2014) Cletiana Gonçalves Fonseca et al.   PLoS One

Dynamic and Permissive Roles of TRPV1 and TRPV4 Channels for Thermosensation in Mouse Supraoptic Magnocellular Neurosecretory Neurons

(2013) Jessica R. Sudbury et al.   JOURNAL OF NEUROSCIENCE

Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively

(2013) C. Zhan et al.   JOURNAL OF NEUROSCIENCE

Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence

(2012) Stephen Whiting et al.   APPETITE

Obesity-programmed mice are rescued by early genetic intervention

(2012) Viviana F. Bumaschny et al.   JOURNAL OF CLINICAL INVESTIGATION

Heteromeric Heat-sensitive Transient Receptor Potential Channels Exhibit Distinct Temperature and Chemical Response

(2011) Wei Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Region-Specific Changes in Transient Receptor Potential Vanilloid Channel Expression in the Vasopressin Magnocellular System in Hepatic Cirrhosis-Induced Hyponatraemia

(2011) T. P. Nedungadi et al.   JOURNAL OF NEUROENDOCRINOLOGY

Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Relative Number and Distribution of Murine Hypothalamic Proopiomelanocortin Neurons Innervating Distinct Target Sites

(2011) Connie M. King et al.   PLoS One

Neuroendocrine Proopiomelanocortin Neurons Are Excited by Hypocretin/Orexin

(2009) C. Acuna-Goycolea et al.   JOURNAL OF NEUROSCIENCE

Proopiomelanocortin Expression in both GABA and Glutamate Neurons

(2009) S. T. Hentges et al.   JOURNAL OF NEUROSCIENCE

Pharmacology of Vanilloid Transient Receptor Potential Cation Channels

(2009) J. Vriens et al.   MOLECULAR PHARMACOLOGY

Human thermoregulatory behavior during rest and exercise — A prospective review

(2009) Zachary J. Schlader et al.   PHYSIOLOGY & BEHAVIOR

Hot flash: TRPV channels in the brain

(2009) Julie A. Kauer et al.   TRENDS IN NEUROSCIENCES

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

(2008) Jennifer W. Hill et al.   JOURNAL OF CLINICAL INVESTIGATION

TRPV1 Gene Required for Thermosensory Transduction and Anticipatory Secretion from Vasopressin Neurons during Hyperthermia

(2008) Reza Sharif-Naeini et al.   NEURON