Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

Neural Control of Energy Balance: Translating Circuits to Therapies

(2015) Laurent Gautron et al.   CELL

The Hunger Genes: Pathways to Obesity

(2015) Agatha A. van der Klaauw et al.   CELL

Neurons for hunger and thirst transmit a negative-valence teaching signal

(2015) J. Nicholas Betley et al.   NATURE

Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity

(2015) Pedro J. Chacón et al.   NEUROBIOLOGY OF AGING

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Identification of a subnuclear body involved in sequence-specific cytokine RNA processing

(2015) Sungwook Lee et al.   Nature Communications

TRAP-seq defines markers for novel populations of hypothalamic and brainstem LepRb neurons

(2015) Margaret B. Allison et al.   Molecular Metabolism

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Molecular Profiling of Neurons Based on Connectivity

(2014) Mats I. Ekstrand et al.   CELL

Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis

(2014) Kevin W. Williams et al.   Cell Metabolism

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Cell-Type-Specific Repression by Methyl-CpG-Binding Protein 2 Is Biased toward Long Genes

(2014) K. Sugino et al.   JOURNAL OF NEUROSCIENCE

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Ablation of AgRP neurons impairs adaption to restricted feeding

(2014) Keith Tan et al.   Molecular Metabolism

Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation

(2013) J. Dalal et al.   GENES & DEVELOPMENT

Forkhead Box O1 (FOXO1) Protein, but Not p53, Contributes to Robust Induction of p21 Expression in Fasted Mice

(2013) Kelsey L. Tinkum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calculating Sample Size Estimates for RNA Sequencing Data

(2013) Steven N. Hart et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse

(2013) Urmi Bandyopadhyay et al.   PLoS One

SynDIG1 Promotes Excitatory Synaptogenesis Independent of AMPA Receptor Trafficking and Biophysical Regulation

(2013) Kathryn L. Lovero et al.   PLoS One

Interleukin-1 Receptor-Associated Kinase-2 (IRAK2) Is a Critical Mediator of Endoplasmic Reticulum (ER) Stress Signaling

(2013) Samir Benosman et al.   PLoS One

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake

(2012) Hongxia Ren et al.   CELL

Neuroendocrine control of female reproductive function by the activin receptor ALK7

(2012) Tatiana Sandoval-Guzmán et al.   FASEB JOURNAL

The human phosphatase interactome: An intricate family portrait

(2012) Francesca Sacco et al.   FEBS LETTERS

The Endoplasmic Reticulum Stress Transducer BBF2H7 Suppresses Apoptosis by Activating the ATF5-MCL1 Pathway in Growth Plate Cartilage

(2012) Soutarou Izumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein

(2012) Takashi Sato et al.   MOLECULAR CELL

Deconstruction of a neural circuit for hunger

(2012) Deniz Atasoy et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone

(2012) Tiemin Liu et al.   NEURON

Antibodies for Assessing Circadian Clock Proteins in the Rodent Suprachiasmatic Nucleus

(2012) Joseph LeSauter et al.   PLoS One

A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death

(2012) Danilo Maddalo et al.   PLoS One

Gene Profiling Reveals a Role for Stress Hormones in the Molecular and Behavioral Response to Food Restriction

(2011) Douglas J. Guarnieri et al.   BIOLOGICAL PSYCHIATRY

Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10

(2011) Peng Cao et al.   CELL

Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop

(2011) Yunlei Yang et al.   CELL

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

Fasting and 17 -Estradiol Differentially Modulate the M-Current in Neuropeptide Y Neurons

(2011) T. A. Roepke et al.   JOURNAL OF NEUROSCIENCE

COP35, a Cholangiocarcinoma-Binding Oligopeptide, Interacts with the Clathrin Heavy Chain Accompanied by GRP78

(2011) H. Kitahara et al.   MOLECULAR CANCER RESEARCH

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

A Quantitative Comparison of Cell-Type-Specific Microarray Gene Expression Profiling Methods in the Mouse Brain

(2011) Benjamin W. Okaty et al.   PLoS One

A Molecular Mechanism for Circadian Clock Negative Feedback

(2011) H. A. Duong et al.   SCIENCE

Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

(2011) Guillaume Rey et al.   PLOS BIOLOGY

Activity-dependent changes in the firing properties of neocortical fast-spiking interneurons in the absence of large changes in gene expression

(2010) Mark N. Miller et al.   Developmental Neurobiology

Identification of the global transcriptomic response of the hypothalamic arcuate nucleus to fasting and leptin

(2010) Zorica Jovanovic et al.   JOURNAL OF NEUROENDOCRINOLOGY

Postsynaptic Clustering and Activation of Pyk2 by PSD-95

(2010) J. A. Bartos et al.   JOURNAL OF NEUROSCIENCE

Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels

(2010) J. Qiu et al.   JOURNAL OF NEUROSCIENCE

SynDIG1: An Activity-Regulated, AMPA- Receptor-Interacting Transmembrane Protein that Regulates Excitatory Synapse Development

(2010) Evgenia Kalashnikova et al.   NEURON

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

(2009) Lale Ozcan et al.   Cell Metabolism

ATM blocks tunicamycin-induced endoplasmic reticulum stress

(2009) Long He et al.   FEBS LETTERS

TDP-43 is recruited to stress granules in conditions of oxidative insult

(2009) Claudia Colombrita et al.   JOURNAL OF NEUROCHEMISTRY

Neuromedin B and Gastrin-Releasing Peptide Excite Arcuate Nucleus Neuropeptide Y Neurons in a Novel Transgenic Mouse Expressing Strong Renilla Green Fluorescent Protein in NPY Neurons

(2009) A. N. van den Pol et al.   JOURNAL OF NEUROSCIENCE

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

(2008) Myriam Heiman et al.   CELL

A FLEX Switch Targets Channelrhodopsin-2 to Multiple Cell Types for Imaging and Long-Range Circuit Mapping

(2008) D. Atasoy et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Critical Role of CDK5 and Polo-like Kinase 2 in Homeostatic Synaptic Plasticity during Elevated Activity

(2008) Daniel P. Seeburg et al.   NEURON

Analysis of Gene Regulatory Networks in the Mammalian Circadian Rhythm

(2008) Jun Yan et al.   PLoS Computational Biology