Lysosome-dependent cell death and deregulated autophagy induced by amine-modified polystyrene nanoparticles

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Silica nanoparticles induce autophagy dysfunction via lysosomal impairment and inhibition of autophagosome degradation in hepatocytes

(2017) Ji Wang et al.   International Journal of Nanomedicine

Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease

(2017) Tim E. Moors et al.   Molecular Neurodegeneration

Lysosomal dysfunction and autophagy blockade contribute to IMB-6G-induced apoptosis in pancreatic cancer cells

(2017) Lu Liu et al.   Scientific Reports

The Intracellular Destiny of the Protein Corona: A Study on its Cellular Internalization and Evolution

(2016) Filippo Bertoli et al.   ACS Nano

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis

(2016) A Ruiz et al.   Cell Death & Disease

Selective autophagy: Lysophagy

(2015) Junya Hasegawa et al.   METHODS

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

(2015) Hui-Wen Chiu et al.   Nanoscale

The autophagic response to polystyrene nanoparticles is mediated by transcription factor EB and depends on surface charge

(2015) Wensi Song et al.   JOURNAL OF NANOBIOTECHNOLOGY

Nanoparticles modulate autophagic effect in a dispersity-dependent manner

(2015) Dengtong Huang et al.   Scientific Reports

Defining and measuring autophagosome flux—concept and reality

(2014) Ben Loos et al.   Autophagy

Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa

(2014) N Rodríguez-Muela et al.   CELL DEATH AND DIFFERENTIATION

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer

(2014) K. L. Cook et al.   CLINICAL CANCER RESEARCH

Low Dose of Amino-Modified Nanoparticles Induces Cell Cycle Arrest

(2013) Jong Ah Kim et al.   ACS Nano

Why should autophagic flux be assessed?

(2013) Xiao-jie Zhang et al.   ACTA PHARMACOLOGICA SINICA

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes

(2013) Fengjuan Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Time resolved study of cell death mechanisms induced by amine-modified polystyrene nanoparticles

(2013) Fengjuan Wang et al.   Nanoscale

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity

(2013) Amruta Manke et al.   Biomed Research International

Nanomaterials and Autophagy: New Insights in Cancer Treatment

(2013) Elisa Panzarini et al.   Cancers

Autophagic dysfunction in a lysosomal storage disorder due to impaired proteolysis

(2012) Matthew J. Elrick et al.   Autophagy

Mitophagy: mechanisms, pathophysiological roles, and analysis

(2012) Wen-Xing Ding et al.   BIOLOGICAL CHEMISTRY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH

(2012) Rikke V Benjaminsen et al.   MOLECULAR THERAPY

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Lysosomal Function and Dysfunction: Mechanism and Disease

(2011) Patricia Boya   ANTIOXIDANTS & REDOX SIGNALING

Lysosomes and lysosomal cathepsins in cell death

(2011) Urška Repnik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation

(2011) Stefaan J. Soenen et al.   Nano Today

Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics

(2011) Anna Salvati et al.   Nanomedicine-Nanotechnology Biology and Medicine

Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles

(2011) Pakatip Ruenraroengsak et al.   Nanotoxicology

Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population

(2011) Jong Ah Kim et al.   Nature Nanotechnology

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Regulation of apoptosis-associated lysosomal membrane permeabilization

(2010) Ann-Charlotte Johansson et al.   APOPTOSIS

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

(2010) C Oberle et al.   CELL DEATH AND DIFFERENTIATION

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

What the Cell “Sees” in Bionanoscience

(2010) Dorota Walczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line

(2010) Mariana G. Bexiga et al.   Nanotoxicology

Endosomal Chloride-Proton Exchange Rather Than Chloride Conductance Is Crucial for Renal Endocytosis

(2010) G. Novarino et al.   SCIENCE

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

What does the cell see?

(2009) Iseult Lynch et al.   Nature Nanotechnology

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

Nanoparticle-induced surface reconstruction of phospholipid membranes

(2008) B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA