Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity

Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity

(2013) Vijay Krishna Raghunathan et al.   BIOMATERIALS

Aptamer-conjugated gold nanoparticles for bioanalysis

(2013) Jiani Zhang et al.   Nanomedicine

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

Oxidative Stress Induced by Pure and Iron-Doped Amorphous Silica Nanoparticles in Subtoxic Conditions

(2012) Dorota Napierska et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidative stress-mediated cytotoxicity and apoptosis induction by TiO2 nanofibers in HeLa cells

(2012) Kunga Mohan Ramkumar et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Aluminium oxide nanoparticles induce mitochondrial-mediated oxidative stress and alter the expression of antioxidant enzymes in human mesenchymal stem cells

(2012) Ali A. Alshatwi et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Nickel oxide nanoparticles induce cytotoxicity, oxidative stress and apoptosis in cultured human cells that is abrogated by the dietary antioxidant curcumin

(2012) Maqsood A. Siddiqui et al.   FOOD AND CHEMICAL TOXICOLOGY

Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice

(2012) Ming-Fen Song et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos

(2012) Ashley R Murray et al.   Particle and Fibre Toxicology

Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

(2012) Anna A. Shvedova et al.   PLoS One

Transient oxidative stress and inflammation after intraperitoneal administration of multiwalled carbon nanotubes functionalized with single strand DNA in rats

(2012) Simona Clichici et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress

(2012) Anna A. Shvedova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways

(2012) Porntipa Chairuangkitti et al.   TOXICOLOGY IN VITRO

Reactive oxygen species-induced cytotoxic effects of zinc oxide nanoparticles in rat retinal ganglion cells

(2012) Dadong Guo et al.   TOXICOLOGY IN VITRO

Enzymatic biosensors based on SWCNT-conducting polymer electrodes

(2011) Alan Le Goff et al.   ANALYST

Carbon nanotubes and pleural damage: Perspectives of nanosafety in the light of asbestos experience

(2011) Giulia M. Stella   Biointerphases

Multiwalled Carbon Nanotubes Induce a Fibrogenic Response by Stimulating Reactive Oxygen Species Production, Activating NF-κB Signaling, and Promoting Fibroblast-to-Myofibroblast Transformation

(2011) Xiaoqing He et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nanoparticle-induced pulmonary toxicity

(2011) Jasmine Jia'en Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Engineered ZnO and TiO2 nanoparticles induce oxidative stress and DNA damage leading to reduced viability of Escherichia coli

(2011) Ashutosh Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell Permeability, Migration, and Reactive Oxygen Species Induced by Multiwalled Carbon Nanotubes in Human Microvascular Endothelial Cells

(2011) M. Pacurari et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Cytotoxic and genotoxic effects of multi-wall carbon nanotubes on human umbilical vein endothelial cells in vitro

(2011) Yuan-Yuan Guo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

ZnO nanorod-induced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax/bcl-2 pathways: role of oxidative stress

(2011) Maqusood Ahamed et al.   Nanomedicine-Nanotechnology Biology and Medicine

Contribution of nano-copper particles toin vivoliver dysfunction and cellular damage: Role of IκBα/NF-κB, MAPKs and mitochondrial signal

(2011) Prasenjit Manna et al.   Nanotoxicology

Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells

(2011) Igor Pujalté et al.   Particle and Fibre Toxicology

Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells

(2011) Maqusood Ahamed et al.   TOXICOLOGY

Multi-walled carbon nanotube-induced gene expression in the mouse lung: Association with lung pathology

(2011) M. Pacurari et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos?

(2011) E.R. Kisin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Titanium dioxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in human amnion epithelial (WISH) cells

(2011) Quaiser Saquib et al.   TOXICOLOGY IN VITRO

Genotoxicity of metal nanoparticles

(2011) Hong Xie et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Functional Assessment of Metal Oxide Nanoparticle Toxicity in Immune Cells

(2010) Melissa A. Maurer-Jones et al.   ACS Nano

Multiwalled carbon nanotubes activate NF-κB and AP-1 signaling pathways to induce apoptosis in rat lung epithelial cells

(2010) Prabakaran Ravichandran et al.   APOPTOSIS

Genotoxic potential of copper oxide nanoparticles in human lung epithelial cells

(2010) Maqusood Ahamed et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and oxidative stress associated with gold nanoparticles

(2010) Jasmine J. Li et al.   BIOMATERIALS

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity

(2010) Helinor J. Johnston et al.   CRITICAL REVIEWS IN TOXICOLOGY

p38 MAPK Activation, DNA Damage, Cell Cycle Arrest and Apoptosis As Mechanisms of Toxicity of Silver Nanoparticles in Jurkat T Cells

(2010) Hyun-Jeong Eom et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Comparative study of the clastogenicity of functionalized and nonfunctionalized multiwalled carbon nanotubes in bone marrow cells of Swiss-Webster mice

(2010) Anita K. Patlolla et al.   ENVIRONMENTAL TOXICOLOGY

Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress

(2010) Naqvi et al.   International Journal of Nanomedicine

Comparative Cytotoxicity of Al2O3, CeO2, TiO2 and ZnO Nanoparticles to Human Lung Cells

(2010) In-Sun Kim et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Pulmonary Inflammation After Intraperitoneal Administration of Ultrafine Titanium Dioxide (TiO2) At Rest or in Lungs Primed with Lipopolysaccharide

(2010) Changsuk Moon et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Direct Fibrogenic Effects of Dispersed Single-Walled Carbon Nanotubes on Human Lung Fibroblasts

(2010) Liying Wang et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

New Insights of Transmembranal Mechanism and Subcellular Localization of Noncovalently Modified Single-Walled Carbon Nanotubes

(2010) Feifan Zhou et al.   NANO LETTERS

Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats

(2010) Jane Y. Ma et al.   Nanotoxicology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Evaluation of oxidative stress and anti-oxidant status in rat serum following exposure of carbon nanotubes

(2010) A. Rama Narsimha Reddy et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Exposure to ZnO nanoparticles induces oxidative stress and cytotoxicity in human colon carcinoma cells

(2010) Barbara De Berardis et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line

(2010) Yiyi Ye et al.   TOXICOLOGY IN VITRO

ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

(2010) Ritesh K. Shukla et al.   TOXICOLOGY IN VITRO

Titanium dioxide nanoparticles cause apoptosis in BEAS-2B cells through the caspase 8/t-Bid-independent mitochondrial pathway

(2010) Yongli Shi et al.   TOXICOLOGY LETTERS

Translocation and extra pulmonary toxicities of multi wall carbon nanotubes in rats

(2010) A. Rama Narsimha Reddy et al.   TOXICOLOGY MECHANISMS AND METHODS

Toxicity of Transition Metal Oxide Nanoparticles: Recent Insights from in vitro Studies

(2010) Yue-Wern Huang et al.   Materials

Oxidative Stress Induced by Zero-Valent Iron Nanoparticles and Fe(II) in Human Bronchial Epithelial Cells

(2009) Christina R. Keenan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

In vitro toxicity of silica nanoparticles in myocardial cells

(2009) Yiyi Ye et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling

(2009) Patrick L Apopa et al.   Particle and Fibre Toxicology

Mesothelioma: Do asbestos and carbon nanotubes pose the same health risk?

(2009) Marie-Claude F Jaurand et al.   Particle and Fibre Toxicology

Induction of chronic inflammation in mice treated with titanium dioxide nanoparticles by intratracheal instillation

(2009) Eun-Jung Park et al.   TOXICOLOGY

Nanoparticles up-regulate tumor necrosis factor-α and CXCL8 via reactive oxygen species and mitogen-activated protein kinase activation

(2009) Hye-Mi Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells

(2009) Baher Fahmy et al.   TOXICOLOGY IN VITRO

Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells

(2009) Fen Wang et al.   TOXICOLOGY IN VITRO

Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles

(2009) Chuan-Chin Huang et al.   TOXICOLOGY IN VITRO

Size-dependent toxicity of metal oxide particles—A comparison between nano- and micrometer size

(2009) Hanna L. Karlsson et al.   TOXICOLOGY LETTERS

Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, Beas-2B

(2009) Hyun-Jeong Eom et al.   TOXICOLOGY LETTERS

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells

(2008) Julie Muller et al.   CARCINOGENESIS

Raw Single-Wall Carbon Nanotubes Induce Oxidative Stress and Activate MAPKs, AP-1, NF-κB, and Akt in Normal and Malignant Human Mesothelial Cells

(2008) Maricica Pacurari et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mechanisms of Fibrogenesis

(2008) Tatiana Kisseleva et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

(2008) Ning Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

The oxidation of glutathione by cobalt/tungsten carbide contributes to hard metal-induced oxidative stress

(2008) Ivana Fenoglio et al.   FREE RADICAL RESEARCH

Acute immunomodulatory effects of iron polyisomaltosate in rats

(2008) Marija Poljak-Blazi et al.   IMMUNOBIOLOGY

New Roles for Copper Metabolism in Cell Proliferation, Signaling, and Disease

(2008) Michelle L. Turski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manufactured nanoparticles: An overview of their chemistry, interactions and potential environmental implications

(2008) Yon Ju-Nam et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Particokinetics and Extrapulmonary Translocation of Intratracheally Instilled Ferric Oxide Nanoparticles in Rats and the Potential Health Risk Assessment

(2008) Mo-Tao Zhu et al.   TOXICOLOGICAL SCIENCES

Oxidative stress induced by cerium oxide nanoparticles in cultured BEAS-2B cells

(2008) Eun-Jung Park et al.   TOXICOLOGY

Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes

(2008) A.R. Murray et al.   TOXICOLOGY

Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: A rapid in vivo screening method for nanotoxicity

(2008) Ronghui Lei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells

(2008) Yi-Hong Hsin et al.   TOXICOLOGY LETTERS