Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors

(2018) Nithya Krishnamurthy et al.   CANCER TREATMENT REVIEWS

Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82

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Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling

(2016) Amnani Aminuddin et al.   Frontiers in Pharmacology

PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas

(2016) Vinay K. Kartha et al.   PLoS One

ASSIGN: context-specific genomic profiling of multiple heterogeneous biological pathways

(2015) Ying Shen et al.   BIOINFORMATICS

A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma

(2015) S. E. Hiemer et al.   MOLECULAR CANCER RESEARCH

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Orthotopic non-metastatic and metastatic oral cancer mouse models

(2015) Manish V. Bais et al.   ORAL ONCOLOGY

Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients

(2015) Swatishree Padhi et al.   Journal of Cancer

Canonical Wnt Pathway Inhibitor ICG-001 Induces Cytotoxicity of Multiple Myeloma Cells in Wnt-Independent Manner

(2015) Eileen R. Grigson et al.   PLoS One

Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin

(2015) King Chi Chan et al.   Scientific Reports

Wnt some lose some: transcriptional governance of stem cells by Wnt/ -catenin signaling

(2014) W.-H. Lien et al.   GENES & DEVELOPMENT

Wnt/β-catenin signalling maintains self-renewal and tumourigenicity of head and neck squamous cell carcinoma stem-like cells by activating Oct4

(2014) Sang Hyuk Lee et al.   JOURNAL OF PATHOLOGY

The CREB-Binding Protein Inhibitor ICG-001 Suppresses Pancreatic Cancer Growth

(2014) M. D. Arensman et al.   MOLECULAR CANCER THERAPEUTICS

Can we safely target the WNT pathway?

(2014) Michael Kahn   NATURE REVIEWS DRUG DISCOVERY

Wnt signaling in stem and cancer stem cells

(2013) Jane D Holland et al.   CURRENT OPINION IN CELL BIOLOGY

Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours

(2013) Peter Wend et al.   EMBO JOURNAL

N-Glycosylation Induces the CTHRC1 Protein and Drives Oral Cancer Cell Migration

(2013) Gangli Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer stem cells and their role in metastasis

(2013) Yusuke Shiozawa et al.   PHARMACOLOGY & THERAPEUTICS

The Small Molecule Wnt Signaling Modulator ICG-001 Improves Contractile Function in Chronically Infarcted Rat Myocardium

(2013) Tomoyo Sasaki et al.   PLoS One

In Vivo Imaging of Tumor-Propagating Cells, Regional Tumor Heterogeneity, and Dynamic Cell Movements in Embryonal Rhabdomyosarcoma

(2012) Myron S. Ignatius et al.   CANCER CELL

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

Cancer Stem Cells: Current Status and Evolving Complexities

(2012) Jane E. Visvader et al.   Cell Stem Cell

Wnt/beta-Catenin Signaling and Small Molecule Inhibitors

(2012) Andrey Voronkov et al.   CURRENT PHARMACEUTICAL DESIGN

The molecular pathogenesis of head and neck squamous cell carcinoma

(2012) S. Michael Rothenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells

(2011) Hunain Alam et al.   MOLECULAR BIOLOGY OF THE CELL

Characterization of Side Populations in HNSCC: Highly Invasive, Chemoresistant and Abnormal Wnt Signaling

(2010) Jun Song et al.   PLoS One

Wnt signaling in stem and cancer stem cells

(2010) Peter Wend et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY