Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-08-12
DOI
10.3389/fphar.2016.00244
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms
- (2015) Laura Novellasdemunt et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells
- (2015) Z. Kabiri et al. BLOOD
- Wnt signaling regulates the stemness of lung cancer stem cells and its inhibitors exert anticancer effect on lung cancer SPC-A1 cells
- (2015) Xueyan Zhang et al. MEDICAL ONCOLOGY
- Wnt addiction of genetically defined cancers reversed by PORCN inhibition
- (2015) B Madan et al. ONCOGENE
- Targeting the Wnt pathway in human cancers: Therapeutic targeting with a focus on OMP-54F28
- (2015) Phuong N. Le et al. PHARMACOLOGY & THERAPEUTICS
- A role for cancer stem cells in therapy resistance: Cellular and molecular mechanisms
- (2015) Monica Cojoc et al. SEMINARS IN CANCER BIOLOGY
- Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment
- (2015) Yue Cheng et al. Oncotarget
- Abstract 1907: Wnt pathway antagonist OMP-54F28 (FZD8-Fc) inhibits tumor growth and reduces tumor-initiating cell frequency in patient-derived hepatocellular carcinoma and ovarian cancer xenograft models
- (2015) Pete Yeung et al. CANCER RESEARCH
- Drug Discovery Approaches to Target Wnt Signaling in Cancer Stem Cells
- (2015) Oncotarget
- Cancer Stem Cells and Stemness Markers in Oral Squamous Cell Carcinomas
- (2014) Shanaya Saurin Patel et al. Asian Pacific Journal of Cancer Prevention
- Updating the Wnt pathways
- (2014) Jia Yu et al. BIOSCIENCE REPORTS
- Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition
- (2014) S Warrier et al. CANCER GENE THERAPY
- Functionalized curcumin analogs as potent modulators of the Wnt/β-catenin signaling pathway
- (2014) Pay-Chin Leow et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Expression of the cancer stem cell markers CD44v6 and ABCG2 in tongue cancer: Effect of neoadjuvant chemotherapy on local recurrence
- (2014) SOUICHI YANAMOTO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Wnt/β-catenin signalling maintains self-renewal and tumourigenicity of head and neck squamous cell carcinoma stem-like cells by activating Oct4
- (2014) Sang Hyuk Lee et al. JOURNAL OF PATHOLOGY
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Both Canonical and Non-Canonical Wnt Signaling Independently Promote Stem Cell Growth in Mammospheres
- (2014) Alexander M. Many et al. PLoS One
- Understanding and targeting cancer stem cells: therapeutic implications and challenges
- (2013) Ke Chen et al. ACTA PHARMACOLOGICA SINICA
- Emodin represses TWIST1-induced epithelial–mesenchymal transitions in head and neck squamous cell carcinoma cells by inhibiting the β-catenin and Akt pathways
- (2013) Tzong-Der Way et al. EUROPEAN JOURNAL OF CANCER
- Honokiol Eliminates Human Oral Cancer Stem-Like Cells Accompanied with Suppression of Wnt/β-Catenin Signaling and Apoptosis Induction
- (2013) Chih-Jung Yao et al. Evidence-based Complementary and Alternative Medicine
- Wnt Pathway Activity in Breast Cancer Sub-Types and Stem-Like Cells
- (2013) Rebecca Lamb et al. PLoS One
- Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
- (2013) J. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer
- (2012) K. D. Proffitt et al. CANCER RESEARCH
- NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells
- (2012) Satoshi Ota et al. EMBO JOURNAL
- All-trans-retinoic acid inhibits growth of head and neck cancer stem cells by suppression of Wnt/β-catenin pathway
- (2012) Young Chang Lim et al. EUROPEAN JOURNAL OF CANCER
- Epithelial to mesenchymal transition in head and neck squamous cell carcinoma
- (2012) Ashley Smith et al. ORAL ONCOLOGY
- Cancer stem cell-like cells from a single cell of oral squamous carcinoma cell lines
- (2011) O. Felthaus et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer stem cells hypothesis and stem cells in head and neck cancers
- (2011) Giuditta Mannelli et al. CANCER TREATMENT REVIEWS
- Isolation and characterization of cancer stem-like side population cells in human oral cancer cells
- (2011) Souichi Yanamoto et al. ORAL ONCOLOGY
- Evidence for Epithelial-Mesenchymal Transition in Cancer Stem Cells of Head and Neck Squamous Cell Carcinoma
- (2011) Chao Chen et al. PLoS One
- An Updated Overview on Wnt Signaling Pathways
- (2010) Tata Purushothama Rao et al. CIRCULATION RESEARCH
- Targeting Wnt Signaling: Can We Safely Eradicate Cancer Stem Cells?
- (2010) F. Takahashi-Yanaga et al. CLINICAL CANCER RESEARCH
- New avenues to target Wnt/β-catenin signaling
- (2010) Folkert Verkaar et al. DRUG DISCOVERY TODAY
- Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance
- (2010) Zhiwei Wang et al. DRUG RESISTANCE UPDATES
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways
- (2010) Naoko Takebe et al. Nature Reviews Clinical Oncology
- Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas
- (2010) Young Chang Lim et al. ORAL ONCOLOGY
- Characterization of Side Populations in HNSCC: Highly Invasive, Chemoresistant and Abnormal Wnt Signaling
- (2010) Jun Song et al. PLoS One
- Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer
- (2010) Randall F Holcombe et al. Cancer Management and Research
- Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-β1 in Renal Tubular Epithelial Cells
- (2009) Guoping Zheng et al. AMERICAN JOURNAL OF PATHOLOGY
- Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes
- (2009) Ping Zhang et al. CANCER LETTERS
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells
- (2009) Pay-Chin Leow et al. INVESTIGATIONAL NEW DRUGS
- Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
- (2009) Shih-Min A. Huang et al. NATURE
- The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/β-catenin pathway
- (2009) M Flahaut et al. ONCOGENE
- A basal-cell-like compartment in head and neck squamous cell carcinomas represents the invasive front of the tumor and is expressing MMP-9
- (2009) Carolina M. Sterz et al. ORAL ONCOLOGY
- GSK3: a multifaceted kinase in Wnt signaling
- (2009) Dianqing Wu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
- (2008) T. T. Onder et al. CANCER RESEARCH
- The cell-cell adhesion molecule E-cadherin
- (2008) F. van Roy et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Stem cell researchers find their niche
- (2008) E. Dzierzak et al. DEVELOPMENT
- Recent Advances in Head and Neck Cancer
- (2008) Robert I. Haddad et al. NEW ENGLAND JOURNAL OF MEDICINE
- The first five years of the Wnt targetome
- (2007) Annica Vlad et al. CELLULAR SIGNALLING
- Mechanisms that mediate stem cell self-renewal and differentiation
- (2007) Haojian Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started