Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks
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Title
Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks
Authors
Keywords
Alzheimer’s disease, GWAS, Transcription factor, Non-coding variation
Journal
Genome Medicine
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-26
DOI
10.1186/s13073-018-0523-8
References
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- (2008) Alan P. Boyle et al. CELL
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