Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks
出版年份 2018 全文链接
标题
Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks
作者
关键词
Alzheimer’s disease, GWAS, Transcription factor, Non-coding variation
出版物
Genome Medicine
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-02-26
DOI
10.1186/s13073-018-0523-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
- (2017) Kuan-lin Huang et al. NATURE NEUROSCIENCE
- Genetic regulatory signatures underlying islet gene expression and type 2 diabetes
- (2017) Arushi Varshney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An environment-dependent transcriptional network specifies human microglia identity
- (2017) David Gosselin et al. SCIENCE
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
- (2016) Jacqueline MacArthur et al. NUCLEIC ACIDS RESEARCH
- Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases
- (2016) Sarah A. Gagliano et al. Annals of Clinical and Translational Neurology
- Convergent genetic and expression data implicate immunity in Alzheimer's disease
- (2015) Lesley Jones et al. Alzheimers & Dementia
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease
- (2015) Elizabeta Gjoneska et al. NATURE
- Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
- (2015) Kyle J Gaulton et al. NATURE GENETICS
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease
- (2015) Hong-Hee Won et al. PLoS Genetics
- SNPsnap: a Web-based tool for identification and annotation of matched SNPs
- (2014) Tune H. Pers et al. BIOINFORMATICS
- Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
- (2014) Valentina Escott-Price et al. PLoS One
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
- (2013) Katrin Kierdorf et al. NATURE NEUROSCIENCE
- Linking disease associations with regulatory information in the human genome
- (2012) M. A. Schaub et al. GENOME RESEARCH
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
- (2011) L. Song et al. GENOME RESEARCH
- Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
- (2011) Sam John et al. NATURE GENETICS
- Inflammatory Bowel Disease
- (2010) Arthur Kaser et al. Annual Review of Immunology
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease
- (2010) Lesley Jones et al. PLoS One
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Isolation of neuronal chromatin from brain tissue
- (2008) Yan Jiang et al. BMC NEUROSCIENCE
- High-Resolution Mapping and Characterization of Open Chromatin across the Genome
- (2008) Alan P. Boyle et al. CELL
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now