GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling

cPLA2α mediates TGF-β-induced epithelial–mesenchymal transition in breast cancer through PI3k/Akt signaling

(2017) Lu Chen et al.   Cell Death & Disease

GRAM domain-containing protein 1B (GRAMD1B), a novel component of the JAK/STAT signaling pathway, functions in gastric carcinogenesis

(2017) Puja Khanna et al.   Oncotarget

Vertical inhibition of the PI3K/Akt/mTOR pathway is synergistic in breast cancer

(2017) S-U Woo et al.   Oncogenesis

TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein

(2017) W H Lee et al.   Oncogenesis

Epithelial-Mesenchymal Transition and Breast Cancer

(2016) Yanyuan Wu et al.   Journal of Clinical Medicine

Constitutive activation of STAT3 in breast cancer cells: A review

(2015) Kasturi Banerjee et al.   INTERNATIONAL JOURNAL OF CANCER

Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching

(2015) Yu Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition

(2015) Wenting Xu et al.   Cell Adhesion & Migration

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer

(2015) Min Soo Kim et al.   Oncotarget

The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis

(2015) Qing Chang et al.   NEOPLASIA

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

(2014) Sherry Y. Wu et al.   Nature Communications

The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers

(2014) Elisavet Paplomata et al.   Therapeutic Advances in Medical Oncology

Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention

(2014) Ailian Xiong et al.   Cancers

Critical role of the WASF3 gene in JAK2/STAT3 regulation of cancer cell motility

(2013) Yong Teng et al.   CARCINOGENESIS

STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits

(2013) SEYUNG S. CHUNG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

RAC1: An Emerging Therapeutic Option for Targeting Cancer Angiogenesis and Metastasis

(2013) H. K. Bid et al.   MOLECULAR CANCER THERAPEUTICS

JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer

(2012) Adrian Britschgi et al.   CANCER CELL

Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer

(2012) T. Sangai et al.   CLINICAL CANCER RESEARCH

Biology and significance of the JAK/STAT signalling pathways

(2012) Hiu Kiu et al.   GROWTH FACTORS

The JAK/STAT Pathway

(2012) D. A. Harrison   Cold Spring Harbor Perspectives in Biology

Akt/PKB-Mediated Phosphorylation of Twist1 Promotes Tumor Metastasis via Mediating Cross-Talk between PI3K/Akt and TGF-β Signaling Axes

(2012) Gongda Xue et al.   Cancer Discovery

The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association

(2011) Madhu Mahankali et al.   CELLULAR SIGNALLING

Stat3 Mediates Expression of Autotaxin in Breast Cancer

(2011) Janeen Azare et al.   PLoS One

The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer

(2010) Carlos A. Castaneda et al.   CANCER AND METASTASIS REVIEWS

Genetic Susceptibility Variants for Chronic Lymphocytic Leukemia

(2010) S. L. Slager et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways

(2009) Davide Schiavone et al.   BIOCHEMICAL JOURNAL

Stat3 promotes directional cell migration by regulating Rac1 activity via its activator  PIX

(2009) T. S. Teng et al.   JOURNAL OF CELL SCIENCE

Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells

(2009) N J Sullivan et al.   ONCOGENE

SOCS regulation of the JAK/STAT signalling pathway

(2008) Ben A. Croker et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Comparative transcriptional profiling and evolutionary analysis of the GRAM domain family in eukaryotes

(2007) Shu-Ye Jiang et al.   DEVELOPMENTAL BIOLOGY