C-reactive protein and pentraxin-3 binding of factor H-like protein 1 differs from complement factor H: implications for retinal inflammation

FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation

(2017) Ádám I. Csincsi et al.   JOURNAL OF IMMUNOLOGY

Complement factor H in host defense and immune evasion

(2016) Raffaella Parente et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pentraxins in the activation and regulation of innate immunity

(2016) Kenji Daigo et al.   IMMUNOLOGICAL REVIEWS

Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation

(2016) Lei Wang et al.   JOURNAL OF PATHOLOGY

Monomeric C-reactive protein and inflammation in age-related macular degeneration

(2016) Kathleen R Chirco et al.   JOURNAL OF PATHOLOGY

Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants

(2016) Blanca Molins et al.   Scientific Reports

Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix

(2015) David C. Briggs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H–like Protein 1 Reveal Functional Determinants of Complement Regulation

(2015) Markus J. Harder et al.   JOURNAL OF IMMUNOLOGY

Age-related macular degeneration and the role of the complement system

(2015) Selina McHarg et al.   MOLECULAR IMMUNOLOGY

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

(2015) Lars G Fritsche et al.   NATURE GENETICS

Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation

(2015) Alex Langford-Smith et al.   Frontiers in Immunology

Systemic and Ocular Long Pentraxin 3 in Patients with Age-Related Macular Degeneration

(2015) Helene Bæk Juel et al.   PLoS One

Dissociation of Pentameric to Monomeric C-Reactive Protein Localizes and Aggravates Inflammation

(2014) Jan R. Thiele et al.   CIRCULATION

Constitutive Expression of Pentraxin 3 (PTX3) Protein by Human Amniotic Membrane Cells Leads to Formation of the Heavy Chain (HC)-Hyaluronan (HA)-PTX3 Complex

(2014) Suzhen Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Incorporation of Pentraxin 3 into Hyaluronan Matrices Is Tightly Regulated and Promotes Matrix Cross-linking

(2014) Natalia S. Baranova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

(2014) L. Deban et al.   JOURNAL OF IMMUNOLOGY

Identification of Factor H–like Protein 1 as the Predominant Complement Regulator in Bruch’s Membrane: Implications for Age-Related Macular Degeneration

(2014) Simon J. Clark et al.   JOURNAL OF IMMUNOLOGY

Genetic variants in the complement system predisposing to age-related macular degeneration: A review

(2014) Elizabeth C. Schramm et al.   MOLECULAR IMMUNOLOGY

Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration

(2014) Simon Clark et al.   Journal of Clinical Medicine

The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules

(2013) Alberto Mantovani et al.   Annals of the New York Academy of Sciences

Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions

(2013) S. J. Clark et al.   JOURNAL OF IMMUNOLOGY

The Role of Complement in Age-Related Macular Degeneration: Heparan Sulphate, a ZIP Code for Complement Factor H?

(2013) Alex Langford-Smith et al.   Journal of Innate Immunity

Long Pentraxin 3/Tumor Necrosis Factor-Stimulated Gene-6 Interaction

(2012) Daria Leali et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

(2012) Reecha Sofat et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

(2012) M. Suzuki et al.   JOURNAL OF CELL SCIENCE

C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration

(2011) I. A. Bhutto et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

(2010) Lars G. Fritsche et al.   HUMAN MOLECULAR GENETICS

Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

(2010) Simon J. Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Angiogenic Inhibitor Long Pentraxin PTX3 Forms an Asymmetric Octamer with Two Binding Sites for FGF2

(2010) Antonio Inforzato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H

(2009) M Mihlan et al.   CELL DEATH AND DIFFERENTIATION

Complement Factor H Binds at Two Independent Sites to C-reactive Protein in Acute Phase Concentrations

(2009) Azubuike I. Okemefuna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6

(2009) Virginia Maina et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The dynamic nature of Bruch's membrane

(2009) J.C. Booij et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration

(2008) S V Goverdhan et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Complement Factor H Binds to Denatured Rather than to Native Pentameric C-reactive Protein

(2008) Svetlana Hakobyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells

(2008) Yuko Yamada et al.   JOURNAL OF NEUROCHEMISTRY