Quercetin inhibits renal cyst growth in vitro and via parenteral injection in a polycystic kidney disease mouse model

Quercetin nanoparticles display antitumor activity via proliferation inhibition and apoptosis induction in liver cancer cells

(2017) Ke-Wei Ren et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Peritoneal Dialysis for Patients with Autosomal Dominant Polycystic Kidney Disease

(2017) Sana Khan et al.   PERITONEAL DIALYSIS INTERNATIONAL

Changes in E-cadherin rigidity sensing regulate cell adhesion

(2017) Caitlin Collins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AXIN1 protects against testicular germ cell tumors via the PI3K/AKT/mTOR signaling pathway

(2017) Hailiang Xu et al.   Oncology Letters

TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein

(2017) W H Lee et al.   Oncogenesis

The effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppression

(2016) Cheng-lin Luo et al.   BIOMEDICINE & PHARMACOTHERAPY

Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells

(2016) Lucia de Stephanis et al.   Clinical and Experimental Nephrology

Molecular mechanisms of action of quercetin in cancer: recent advances

(2016) Dharambir Kashyap et al.   TUMOR BIOLOGY

mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex

(2016) Monika Pema et al.   Nature Communications

Tolvaptan: A Review in Autosomal Dominant Polycystic Kidney Disease

(2015) Hannah A. Blair et al.   DRUGS

Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells

(2015) Jen X. Xu et al.   PHYSIOLOGICAL GENOMICS

Steviol retards renal cyst growth through reduction of CFTR expression and inhibition of epithelial cell proliferation in a mouse model of polycystic kidney disease

(2014) Chaowalit Yuajit et al.   BIOCHEMICAL PHARMACOLOGY

Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease

(2014) Peter C. Harris et al.   JOURNAL OF CLINICAL INVESTIGATION

Vangl2 Regulates E-Cadherin in Epithelial Cells

(2014) Tadahiro Nagaoka et al.   Scientific Reports

Inhibition of Akt/mTOR Signaling by the Dietary Flavonoid Fisetin

(2013) Deeba Syed et al.   Anti-Cancer Agents in Medicinal Chemistry

Type of PKD1 Mutation Influences Renal Outcome in ADPKD

(2013) E. Cornec-Le Gall et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Strategies Targeting cAMP Signaling in the Treatment of Polycystic Kidney Disease

(2013) V. E. Torres et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dietary flavonoid fisetin: A novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management

(2012) Vaqar Mustafa Adhami et al.   BIOCHEMICAL PHARMACOLOGY

Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway

(2012) Tao Xu et al.   MOLECULAR BIOLOGY REPORTS

Drug discovery for polycystic kidney disease

(2011) Ying Sun et al.   ACTA PHARMACOLOGICA SINICA

Polycystic kidney disease and therapeutic approaches

(2011) Eun-Young Park et al.   BMB Reports

Polycystin-1, 2, and STIM1 Interact with IP3R to Modulate ER Ca2+ Release through the PI3K/Akt Pathway

(2011) Netty G. Santoso et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nutritional Approaches to Modulate Oxidative Stress in Alzheimers Disease

(2011) C. B. Pocernich et al.   Current Alzheimer Research

Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation

(2011) Liwei Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanism of the Mesenchymal-Epithelial Transition and Its Relationship with Metastatic Tumor Formation

(2011) D. Yao et al.   MOLECULAR CANCER RESEARCH

Polycystins and Primary Cilia: Primers for Cell Cycle Progression

(2009) Jing Zhou   Annual Review of Physiology

Chemoprotective Mechanism of the Natural Compounds, Epigallocatechin- 3-O-Gallate, Quercetin and Curcumin Against Cancer and Cardiovascular Diseases

(2009) Smita Jagtap et al.   CURRENT MEDICINAL CHEMISTRY

Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways

(2009) H. Happe et al.   HUMAN MOLECULAR GENETICS

Nanomolar Potency Pyrimido-pyrrolo-quinoxalinedione CFTR Inhibitor Reduces Cyst Size in a Polycystic Kidney Disease Model

(2009) Lukmanee Tradtrantip et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting Cyst Initiation in ADPKD

(2009) S. J. Leuenroth et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activation of the AKT/mTOR pathway in autosomal recessive polycystic kidney disease (ARPKD)

(2009) D.-C. Fischer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

Multitargeted cancer prevention by quercetin

(2008) Akira Murakami et al.   CANCER LETTERS

Strategies to Inhibit Cyst Formation in ADPKD

(2008) J. P. Calvet   Clinical Journal of the American Society of Nephrology

Small-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease

(2008) B. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY