Molecular mechanisms of action of quercetin in cancer: recent advances
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanisms of action of quercetin in cancer: recent advances
Authors
Keywords
Quercetin, Apoptosis, Cell cycle, Anti-angiogenesis, Anti-metastasis, Toxicity
Journal
TUMOR BIOLOGY
Volume 37, Issue 10, Pages 12927-12939
Publisher
Springer Nature
Online
2016-07-22
DOI
10.1007/s13277-016-5184-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Comparison of poly(ε-caprolactone) chain lengths of poly(ε-caprolactone)-co-d-α-tocopheryl-poly(ethylene glycol) 1000 succinate nanoparticles for enhancement of quercetin delivery to SKBR3 breast cancer cells
- (2016) Jiraphong Suksiriworapong et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Quercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathway
- (2016) Xin-Rong Xu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Ursolic acid (UA): A metabolite with promising therapeutic potential
- (2016) Dharambir Kashyap et al. LIFE SCIENCES
- Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives
- (2016) Gaurav Kumar et al. LIFE SCIENCES
- Complete Response and Fatigue Improvement With the Combined Use of Cyclophosphamide and Quercetin in a Patient With Metastatic Bladder Cancer
- (2016) Giuseppe Di Lorenzo et al. MEDICINE
- Effect of Quercetin-loaded liposomes on induced oxidative stress in human spermatozoa
- (2016) Elena Moretti et al. REPRODUCTIVE TOXICOLOGY
- The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis
- (2015) Guohua Lou et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Protection of Quercetin against Triptolide-induced apoptosis by suppressing oxidative stress in rat Leydig cells
- (2015) Jie Hu et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Quercetin in Cancer Treatment, Alone or in Combination with Conventional Therapeutics?
- (2015) Ana Brito et al. CURRENT MEDICINAL CHEMISTRY
- Exploring quercetin and luteolin derivatives as antiangiogenic agents
- (2015) Divyashree Ravishankar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The combination of resveratrol and quercetin enhances the individual effects of these molecules on triacylglycerol metabolism in white adipose tissue
- (2015) Noemí Arias et al. EUROPEAN JOURNAL OF NUTRITION
- Antiproliferative activity of long chain acylated esters of quercetin-3-O-glucoside in hepatocellular carcinoma HepG2 cells
- (2015) Sudhanshu Sudan et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Quercetin tests negative for genotoxicity in transcriptome analyses of liver and small intestine of mice
- (2015) Elise F. Hoek-van den Hil et al. FOOD AND CHEMICAL TOXICOLOGY
- Quercetin protects mouse liver against nickel-induced DNA methylation and inflammation associated with the Nrf2/HO-1 and p38/STAT1/NF-κB pathway
- (2015) Chan-Min Liu et al. FOOD AND CHEMICAL TOXICOLOGY
- The involvement of p62–Keap1–Nrf2 antioxidative signaling pathway and JNK in the protection of natural flavonoid quercetin against hepatotoxicity
- (2015) Li-Li Ji et al. FREE RADICAL BIOLOGY AND MEDICINE
- Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines
- (2015) Maria Grazia Refolo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Molecular aspects of metal oxide nanoparticle (MO-NPs) mediated pharmacological effects
- (2015) Hardeep Singh Tuli et al. LIFE SCIENCES
- Molecular aspects of melatonin (MLT)-mediated therapeutic effects
- (2015) Hardeep Singh Tuli et al. LIFE SCIENCES
- Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion
- (2015) Hui-Hui Cao et al. Molecular Cancer
- Nrf2 Expression and Apoptosis in Quercetin-treated Malignant Mesothelioma Cells
- (2015) Yoon-Jin Lee et al. MOLECULES AND CELLS
- Quercetin Enhances Cisplatin Sensitivity of Human Osteosarcoma Cells by Modulating microRNA-217-KRAS Axis
- (2015) Xian Zhang et al. MOLECULES AND CELLS
- Magnetoelectric ‘spin’ on stimulating the brain
- (2015) Rakesh Guduru et al. Nanomedicine
- Quercetin Inhibits Vascular Endothelial Growth Factor-Induced Choroidal and Retinal Angiogenesis in vitro
- (2015) Fangting Li et al. OPHTHALMIC RESEARCH
- Quercetin Affects Hsp70/IRE1αMediated Protection from Death Induced by Endoplasmic Reticulum Stress
- (2015) Antonello Storniolo et al. Oxidative Medicine and Cellular Longevity
- Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1
- (2015) Grace Y. Sun et al. PLoS One
- Isothiocyanates: a class of bioactive metabolites with chemopreventive potential
- (2015) Gaurav Kumar et al. TUMOR BIOLOGY
- Apoptotic effect of cordycepin on A549 human lung cancer cell line
- (2015) Hardeep Singh TULI et al. TURKISH JOURNAL OF BIOLOGY
- Substance Use and Dual Diagnosis Disorders: Future Epidemiology, Determinants, and Policies
- (2015) Sahoo Saddichha et al. Biomed Research International
- Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells
- (2015) Santhalakshmi Ranganathan et al. PLoS One
- Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft
- (2014) Wei-Jiunn Lee et al. ARCHIVES OF TOXICOLOGY
- Inhibition of protein kinase CK2 by quercetin enhances CD95-mediated apoptosis in a human thymus-derived T cell line
- (2014) Maria Russo et al. FOOD RESEARCH INTERNATIONAL
- Quercetin alleviates myocyte toxic and sensitizes anti-leukemic effect of adriamycin
- (2014) Yanqiu Han et al. Hematology
- Microbial pigments as natural color sources: current trends and future perspectives
- (2014) Hardeep S. Tuli et al. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
- The effect of quercetin and imperatorin on programmed cell death induction in T98G cells in vitro
- (2014) Dorota Bądziul et al. Pharmacological Reports
- Antigenotoxic potential of rutin and quercetin in Swiss mice exposed to gamma radiation
- (2014) ShrikantL Patil et al. Biomedical Journal
- Quercetin protects rat dorsal root ganglion neurons against high glucose-induced injury in vitro through Nrf-2/HO-1 activation and NF-κB inhibition
- (2013) Yue Shi et al. ACTA PHARMACOLOGICA SINICA
- Quercetin exerts anti-melanoma activities and inhibits STAT3 signaling
- (2013) Hui-Hui Cao et al. BIOCHEMICAL PHARMACOLOGY
- Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothelial cells
- (2013) Daxian Zhao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Quercetin Induces Apoptosis via the Mitochondrial Pathway in KB and KBv200 Cells
- (2013) Jian-ye Zhang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Cordycepin: A bioactive metabolite with therapeutic potential
- (2013) Hardeep S. Tuli et al. LIFE SCIENCES
- Quercetin prevents liver carcinogenesis by inducing cell cycle arrest, decreasing cell proliferation and enhancing apoptosis
- (2013) María Laura Casella et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Quercetin and EGCG Exhibit Chemopreventive Effects in Cholangiocarcinoma Cells via Suppression of JAK/STAT Signaling Pathway
- (2013) Laddawan Senggunprai et al. PHYTOTHERAPY RESEARCH
- Quercetin Enhances the Antitumor Activity of Trichostatin A through Upregulation of p53 Protein Expression In Vitro and In Vivo
- (2013) Shu-Ting Chan et al. PLoS One
- Newly discovered angiogenesis inhibitors and their mechanisms of action
- (2012) Ze-hong Miao et al. ACTA PHARMACOLOGICA SINICA
- Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes
- (2012) Shing-Chuan Shen et al. EXPERIMENTAL DERMATOLOGY
- ERK1/2 activation in quercetin-treated BEAS-2B cell plays a role in Nrf2-driven HO-1 expression
- (2012) Yoon-Jin Lee et al. Molecular & Cellular Toxicology
- The Influence of Curcumin, Quercetin, and Eicosapentaenoic Acid on the Expression of Phase II Detoxification Enzymes in the Intestinal Cell Lines HT-29, Caco-2, HuTu 80, and LT97
- (2012) Julia Odenthal et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways
- (2012) Poyil Pratheeshkumar et al. PLoS One
- Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin
- (2011) Jun-Shik Choi et al. ARCHIVES OF PHARMACAL RESEARCH
- Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38
- (2011) Ana Belén Granado-Serrano et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids
- (2011) Emilia Kansanen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
- (2011) Keiko Taguchi et al. GENES TO CELLS
- Quercetin and Rutin Reduced the Bioavailability of Cyclosporine from Neoral, an Immunosuppressant, through Activating P-Glycoprotein and CYP 3A4
- (2011) Chung-Ping Yu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Quercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells
- (2010) G. Niu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells
- (2010) Chu-Chung Chou et al. ARCHIVES OF PHARMACAL RESEARCH
- Induction of apoptosis by quercetin is mediated through AMPKα1/ASK1/p38 pathway
- (2010) Yun-Kyoung Lee et al. CANCER LETTERS
- The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition
- (2010) R. Vidya Priyadarsini et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Quercetin and naringenin reduce abnormal development of mouse embryos produced by hydroxyurea
- (2010) Ricardo Pérez-Pastén et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Protective effects of quercetin on liver injury induced by ethanol
- (2010) Xi Chen Pharmacognosy Magazine
- Prenatal Exposure to Flavonoids: Implication for Cancer Risk
- (2010) Kimberly Vanhees et al. TOXICOLOGICAL SCIENCES
- Protective Mechanism of Quercetin and Rutin Using Glutathione Metabolism on H2O2-induced Oxidative Stress in HepG2 Cells
- (2009) Gyo-Nam Kim et al. Annals of the New York Academy of Sciences
- SIMULTANEOUS ACTION OF THE FLAVONOID QUERCETIN ON CYTOCHROME P450 (CYP) 1A2, CYP2A6,N-ACETYLTRANSFERASE AND XANTHINE OXIDASE ACTIVITY IN HEALTHY VOLUNTEERS
- (2009) Yao Chen et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers
- (2009) Kyoung-Ah Kim et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Effects of the flavonol quercetin on the bioavailability of simvastatin in pigs
- (2009) Rainer Cermak et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells
- (2009) Su-Yu Chien et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Nrf2-dependent and -independent Responses to Nitro-fatty Acids in Human Endothelial Cells
- (2009) Emilia Kansanen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dietary chemoprevention strategies for induction of phase II xenobiotic-metabolizing enzymes in lung carcinogenesis: A review
- (2009) Xiang-Lin Tan et al. LUNG CANCER
- Angiogenesis and Anti-Angiogenic Molecularly Targeted Therapies in Malignant Gliomas
- (2009) Andreas A. Argyriou et al. ONCOLOGY
- Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis
- (2009) Qiang Zhang et al. TOXICOLOGY IN VITRO
- Quercetin pretreatment increases the bioavailability of pioglitazone in rats: Involvement of CYP3A inhibition
- (2008) Sudhir N. Umathe et al. BIOCHEMICAL PHARMACOLOGY
- Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib
- (2008) F.-T. Liu et al. BLOOD
- Raf and MEK Protein Kinases Are Direct Molecular Targets for the Chemopreventive Effect of Quercetin, a Major Flavonol in Red Wine
- (2008) K. W. Lee et al. CANCER RESEARCH
- Quercetin inhibition of tumor invasion via suppressing PKC /ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells
- (2008) C.-W. Lin et al. CARCINOGENESIS
- Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression
- (2008) Jae-Hoon Jeong et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Quercetin inhibits lymphocyte activation and proliferation without inducing apoptosis in peripheral mononuclear cells
- (2008) Enrico Lugli et al. LEUKEMIA RESEARCH
- Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: Possible contribution of P-glycoprotein
- (2008) Tripta Bansal et al. LIFE SCIENCES
- Antiangiogenic effects of flavonoids and chalcones
- (2008) J MOJZIS et al. PHARMACOLOGICAL RESEARCH
- The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90
- (2008) Ravikumar Aalinkeel et al. PROSTATE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now