Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells

The effect of tolvaptan on autosomal dominant polycystic kidney disease patients: a subgroup analysis of the Japanese patient subset from TEMPO 3:4 trial

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Therapeutic Advances in the Treatment of Polycystic Kidney Disease

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Genetics and Pathogenesis of Autosomal Dominant Polycystic Kidney Disease: 20 Years On

(2014) Emilie Cornec-Le Gall et al.   HUMAN MUTATION

Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease

(2014) Peter C. Harris et al.   JOURNAL OF CLINICAL INVESTIGATION

Tolvaptan plus Pasireotide Shows Enhanced Efficacy in a PKD1 Model

(2014) K. Hopp et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multidrug Therapy for Polycystic Kidney Disease: A Review and Perspective

(2013) Gianluca Aguiari et al.   AMERICAN JOURNAL OF NEPHROLOGY

Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease

(2013) Kevin F. Erickson et al.   ANNALS OF INTERNAL MEDICINE

Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial

(2013) Anna Caroli et al.   LANCET

Polycystin-1 regulates amphiregulin expression through CREB and AP1 signalling: implications in ADPKD cell proliferation

(2012) Gianluca Aguiari et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease

(2012) Vicente E. Torres et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resveratrol Inhibits Inflammatory Responses via the Mammalian Target of Rapamycin Signaling Pathway in Cultured LPS-Stimulated Microglial Cells

(2012) Lian-Mei Zhong et al.   PLoS One

Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease

(2010) Andreas L. Serra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

(2010) Gerd Walz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nephrocystin-1 Forms a Complex with Polycystin-1 via a Polyproline Motif/SH3 Domain Interaction and Regulates the Apoptotic Response in Mammals

(2010) Claas Wodarczyk et al.   PLoS One

Deficiency of polycystic kidney disease-1 gene (PKD1) expression increases A3 adenosine receptors in human renal cells: Implications for cAMP-dependent signalling and proliferation of PKD1-mutated cystic cells

(2009) Gianluca Aguiari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1

(2008) Sekiya Shibazaki et al.   HUMAN MOLECULAR GENETICS

Triptolide Reduces Cystogenesis in a Model of ADPKD

(2008) S. J. Leuenroth et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY