Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation

(2017) Pankaj Kumar et al.   MOLECULAR CANCER RESEARCH

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

(2017) Kristen M. Turner et al.   NATURE

Environmental change drives accelerated adaptation through stimulated copy number variation

(2017) Ryan M. Hull et al.   PLOS BIOLOGY

Sequencing the extrachromosomal circular mobilome reveals retrotransposon activity in plants

(2017) Sophie Lanciano et al.   PLoS Genetics

Characterization of the microDNA through the response to chemotherapeutics in lymphoblastoid cell lines

(2017) Pamela Mehanna et al.   PLoS One

w4CSeq: software and web application to analyze 4C-seq data

(2016) Mingyang Cai et al.   BIOINFORMATICS

Assessment of megabase-scale somatic copy number variation using single-cell sequencing

(2016) Kristin A. Knouse et al.   GENOME RESEARCH

A reference data set of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree

(2016) Michael A. Eberle et al.   GENOME RESEARCH

Detecting circular RNAs: bioinformatic and experimental challenges

(2016) Linda Szabo et al.   NATURE REVIEWS GENETICS

Epigenetic Repeat-Induced Gene Silencing in the Chromosomal and Extrachromosomal Contexts in Human Cells

(2016) Sho-hei Mitsuda et al.   PLoS One

Overview of recurrent chromosomal losses in retinoblastoma detected by low coverage next generation sequencing

(2016) A.J. García-Chequer et al.   Cancer Genetics

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells

(2016) Henrik D. Møller et al.   Jove-Journal of Visualized Experiments

Extrachromosomal circular DNA is common in yeast

(2015) Henrik D. Møller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOL1 Kidney Disease Risk Variants: An Evolving Landscape

(2015) Patrick D. Dummer et al.   SEMINARS IN NEPHROLOGY

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

(2015) Søren Besenbacher et al.   Nature Communications

Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity

(2015) Laura W. Dillon et al.   Cell Reports

Formation of Extrachromosomal Circular DNA from Long Terminal Repeats of Retrotransposons in Saccharomyces cerevisiae

(2015) Henrik D. Møller et al.   G3-Genes Genomes Genetics

Rapid Evolution of Recombinant Saccharomyces cerevisiae for Xylose Fermentation through Formation of Extra-chromosomal Circular DNA

(2015) Mekonnen M. Demeke et al.   PLoS Genetics

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression

(2014) K. Skourti-Stathaki et al.   GENES & DEVELOPMENT

Resolving the complexity of the human genome using single-molecule sequencing

(2014) Mark J. P. Chaisson et al.   NATURE

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma

(2014) Nicolas Vogt et al.   NUCLEIC ACIDS RESEARCH

An Improved Method for Including Upper Size Range Plasmids in Metamobilomes

(2014) Anders Norman et al.   PLoS One

A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection

(2014) Steve Hoffmann et al.   GENOME BIOLOGY

Life style and longevity among initially healthy middle-aged men: prospective cohort study

(2013) Trond Heir et al.   BMC PUBLIC HEALTH

De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes

(2013) Jing Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

The Database of Genomic Variants: a curated collection of structural variation in the human genome

(2013) Jeffrey R. MacDonald et al.   NUCLEIC ACIDS RESEARCH

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

(2013) David A. Nathanson et al.   SCIENCE

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

BEDOPS: high-performance genomic feature operations

(2012) Shane Neph et al.   BIOINFORMATICS

Serial translocation by means of circular intermediates underlies colour sidedness in cattle

(2012) Keith Durkin et al.   NATURE

Extrachromosomal MicroDNAs and Chromosomal Microdeletions in Normal Tissues

(2012) Y. Shibata et al.   SCIENCE

Human Copy Number Variation and Complex Genetic Disease

(2011) Santhosh Girirajan et al.   Annual Review of Genetics

Pybedtools: a flexible Python library for manipulating genomic datasets and annotations

(2011) Ryan K. Dale et al.   BIOINFORMATICS

Mechanisms of ring chromosome formation, ring instability and clinical consequences

(2011) Roberta S Guilherme et al.   BMC Medical Genetics

Amplification of a Zygosaccharomyces bailii DNA Segment in Wine Yeast Genomes by Extrachromosomal Circular DNA Formation

(2011) Virginie Galeote et al.   PLoS One

Gene amplification as double minutes or homogeneously staining regions in solid tumors: Origin and structure

(2010) C. T. Storlazzi et al.   GENOME RESEARCH

Metastasis-Inducing S100A4 and RANTES Cooperate in Promoting Tumor Progression in Mice

(2010) Birgitte Forst et al.   PLoS One

Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus

(2010) D. Gresham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cells

(2010) Sarit Cohen et al.   Mobile DNA

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and Metastasis

(2009) K. Pedersen et al.   MOLECULAR AND CELLULAR BIOLOGY

Survey of extrachromosomal circular DNA derived from plant satellite repeats

(2008) Alice Navrátilová et al.   BMC PLANT BIOLOGY