A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
Published 2018 View Full Article
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Title
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-06
DOI
10.1038/s41467-018-03061-x
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Note: Only part of the references are listed.- Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin
- (2017) Esben G. W. Schmidt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics
- (2017) Nicole M. Piche-Nicholas et al. mAbs
- Chaperone proteins as single component reagents to assess antibody nonspecificity
- (2017) Ryan L. Kelly et al. mAbs
- Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
- (2017) Michal Pyzik et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
- (2016) Stian Foss et al. JOURNAL OF IMMUNOLOGY
- The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery
- (2015) Malin Bern et al. JOURNAL OF CONTROLLED RELEASE
- Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions
- (2015) Algirdas Grevys et al. JOURNAL OF IMMUNOLOGY
- Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs
- (2015) Derry C Roopenian et al. mAbs
- High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice
- (2015) Ryan L Kelly et al. mAbs
- Targeting FcRn for the modulation of antibody dynamics
- (2015) E. Sally Ward et al. MOLECULAR IMMUNOLOGY
- Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
- (2015) Angela Schoch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling
- (2014) M. Jack Borrok et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dissection of the Neonatal Fc Receptor (FcRn)-Albumin Interface Using Mutagenesis and Anti-FcRn Albumin-blocking Antibodies
- (2014) Kine Marita Knudsen Sand et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms
- (2014) Vaheh Oganesyan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interaction with Both Domain I and III of Albumin Is Required for Optimal pH-dependent Binding to the Neonatal Fc Receptor (FcRn)
- (2014) Kine Marita Knudsen Sand et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding
- (2014) Jan Terje Andersen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge
- (2014) Bing Li et al. mAbs
- Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2014) Pernille Foged Jensen et al. MOLECULAR & CELLULAR PROTEOMICS
- There’s been a Flaw in Our Thinking
- (2014) Clark L. Anderson Frontiers in Immunology
- A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults
- (2013) Gabriel J. Robbie et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- An automated immunoassay for early specificity profiling of antibodies
- (2013) Katrin Frese et al. mAbs
- Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies
- (2013) Tilman Schlothauer et al. mAbs
- Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules
- (2013) Andrew W. Weflen et al. MOLECULAR BIOLOGY OF THE CELL
- Monoclonal antibodies directed against human FcRn and their applications
- (2012) Gregory J. Christianson et al. mAbs
- A strategy for risk mitigation of antibodies with fast clearance
- (2012) Isidro Hötzel et al. mAbs
- Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
- (2012) Jan Terje Andersen et al. Nature Communications
- Neonatal Fc Receptor Blockade by Fc Engineering Ameliorates Arthritis in a Murine Model
- (2011) D. A. Patel et al. JOURNAL OF IMMUNOLOGY
- Clinical chemistry of human FcRn transgenic mice
- (2011) Carsten Stein et al. MAMMALIAN GENOME
- Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
- (2011) Nigel M. Stapleton et al. Nature Communications
- Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization
- (2010) Tomoyuki Igawa et al. NATURE BIOTECHNOLOGY
- Enhanced antibody half-life improves in vivo activity
- (2010) Jonathan Zalevsky et al. NATURE BIOTECHNOLOGY
- Development trends for human monoclonal antibody therapeutics
- (2010) Aaron L. Nelson et al. NATURE REVIEWS DRUG DISCOVERY
- Reduced elimination of IgG antibodies by engineering the variable region
- (2010) T. Igawa et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Protein-binding assays in biological liquids using microscale thermophoresis
- (2010) Christoph J. Wienken et al. Nature Communications
- Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding
- (2009) Jan Terje Andersen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice
- (2009) Héctor Pérez Montoyo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analyses of the Recycling Receptor, FcRn, in Live Cells Reveal Novel Pathways for Lysosomal Delivery
- (2009) Zhuo Gan et al. TRAFFIC
- Neonatal Fc Receptor Mediates Internalization of Fc in Transfected Human Endothelial Cells
- (2008) Nancy A. Goebl et al. MOLECULAR BIOLOGY OF THE CELL
- Dependence of antibody-mediated presentation of antigen on FcRn
- (2008) S.-W. Qiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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