High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice

Plasmonic measurements of monoclonal antibody self-association using self-interaction nanoparticle spectroscopy

(2014) Jayapriya Jayaraman et al.   BIOTECHNOLOGY AND BIOENGINEERING

Improving Monoclonal Antibody Selection and Engineering using Measurements of Colloidal Protein Interactions

(2014) Steven B. Geng et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In silico selection of therapeutic antibodies for development: Viscosity, clearance, and chemical stability

(2014) Vikas K. Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Death receptor 5 agonistic antibody PRO95780: preclinical pharmacokinetics and concentration–effect relationship support clinical dose and regimen selection

(2013) Hong Xiang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

High throughput solution-based measurement of antibody-antigen affinity and epitope binning

(2013) Patricia Estep et al.   mAbs

High throughput detection of antibody self-interaction by bio-layer interferometry

(2013) Tingwan Sun et al.   mAbs

Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates

(2013) Shantanu V. Sule et al.   MOLECULAR PHARMACEUTICS

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

(2013) Y. Xu et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A strategy for risk mitigation of antibodies with fast clearance

(2012) Isidro Hötzel et al.   mAbs

High-Throughput Analysis of Concentration-Dependent Antibody Self-Association

(2011) Shantanu V. Sule et al.   BIOPHYSICAL JOURNAL

Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences

(2011) W. Wang et al.   DRUG METABOLISM AND DISPOSITION

Fc domain mediated self-association of an IgG1 monoclonal antibody under a low ionic strength condition

(2011) Hirotaka Nishi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR

(2010) Takuo Suzuki et al.   JOURNAL OF IMMUNOLOGY

Enhanced antibody half-life improves in vivo activity

(2010) Jonathan Zalevsky et al.   NATURE BIOTECHNOLOGY

Reduced elimination of IgG antibodies by engineering the variable region

(2010) T. Igawa et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Cross-Interaction Chromatography: A Rapid Method to Identify Highly Soluble Monoclonal Antibody Candidates

(2009) Steven A. Jacobs et al.   PHARMACEUTICAL RESEARCH