Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin

Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs

(2016) Dorthe Viuff et al.   JOURNAL OF CONTROLLED RELEASE

A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine

(2015) Mark E. B. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bio-reduction of Redox-Sensitive Albumin Conjugates in FcRn-Expressing Cells

(2014) Lorine Brülisauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

(2014) Vaheh Oganesyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding

(2014) Jan Terje Andersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Podocytes Degrade Endocytosed Albumin Primarily in Lysosomes

(2014) John M. Carson et al.   PLoS One

Albumin Is Recycled from the Primary Urine by Tubular Transcytosis

(2013) V. Tenten et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules

(2013) Andrew W. Weflen et al.   MOLECULAR BIOLOGY OF THE CELL

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

(2012) Jan Terje Andersen et al.   Nature Communications

Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal Tubule

(2010) S. Amsellem et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The production, characterisation and enhanced pharmacokinetics of scFv–albumin fusions expressed in Saccharomyces cerevisiae

(2010) Leslie Evans et al.   PROTEIN EXPRESSION AND PURIFICATION

Addition of a cysteine to glucagon-like peptide-1 (GLP-1) conjugates GLP-1 to albumin in serum and prolongs GLP-1 action in vivo

(2010) Ye-Lin Wu et al.   REGULATORY PEPTIDES

An Albumin-Conjugated Peptide Exhibits Potent Anti-HIV Activity and Long In Vivo Half-Life

(2009) D. Xie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity

(2009) Salit Tzaban et al.   JOURNAL OF CELL BIOLOGY

Analyses of the Recycling Receptor, FcRn, in Live Cells Reveal Novel Pathways for Lysosomal Delivery

(2009) Zhuo Gan et al.   TRAFFIC

An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis

(2008) Laurie L. Baggio et al.   GASTROENTEROLOGY