MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis

CD100–Plexin-B2 Promotes the Inflammation in Psoriasis by Activating NF-κB and the Inflammasome in Keratinocytes

(2018) Chen Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin

(2017) Julie Deckers et al.   IMMUNOLOGICAL REVIEWS

Psoriasis pathogenesis and the development of novel targeted immune therapies

(2017) Jason E. Hawkes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Oxidative stress drives CD8 + T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes

(2017) Shuli Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Semaphorin4D Drives CD8 + T-Cell Lesional Trafficking in Oral Lichen Planus via CXCL9/CXCL10 Upregulations in Oral Keratinocytes

(2017) Yao Ke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TGFβ/SMAD/microRNA-486-3p Signaling Axis Mediates Keratin 17 Expression and Keratinocyte Hyperproliferation in Psoriasis

(2017) Man Jiang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17

(2017) Luting Yang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Efficacy and safety of adalimumab every other week versus methotrexate once weekly in children and adolescents with severe chronic plaque psoriasis: a randomised, double-blind, phase 3 trial

(2017) Kim Papp et al.   LANCET

Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23–dependent murine model

(2017) A. E. Getschman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain

(2017) Atsushi Sakai et al.   Nature Communications

miR-17-92/p38α Dysregulation Enhances Wnt Signaling and Selects Lgr6+Cancer Stem-like Cells during Lung Adenocarcinoma Progression

(2016) Anna Guinot et al.   CANCER RESEARCH

New Insights Into miR-17–92 Cluster Regulation and Angiogenesis

(2016) Jan Fiedler et al.   CIRCULATION RESEARCH

miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice

(2016) Dinghong Wu et al.   EXPERIMENTAL DERMATOLOGY

Streptococcus pyogenes –induced cutaneous lymphocyte antigen–positive T cell–dependent epidermal cell activation triggers T H 17 responses in patients with guttate psoriasis

(2016) Ester Ruiz-Romeu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CX3CR1 deficiency attenuates imiquimod-induced psoriasis-like skin inflammation with decreased M1 macrophages

(2016) Sohshi Morimura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts

(2016) Nahid Akhtar et al.   JOURNAL OF IMMUNOLOGY

Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic miR-17-92 cluster expression

(2016) R Urtasun et al.   ONCOGENE

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

miRNA Biogenesis: A Dynamic Pathway

(2016) Natalia P. Achkar et al.   TRENDS IN PLANT SCIENCE

A review of the roles of keratinocyte-derived cytokines and chemokines in the pathogenesis of atopic dermatitis in humans and dogs

(2016) Ryota Asahina et al.   VETERINARY DERMATOLOGY

A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

(2016) Eric A. Hungate et al.   Nature Communications

Regulators of Tfh Cell Differentiation

(2016) Gajendra M. Jogdand et al.   Frontiers in Immunology

The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells

(2015) Michele Cioffi et al.   GUT

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth

(2015) Marija Mihailovich et al.   Nature Communications

CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma

(2015) A. S. McNeal et al.   Cancer Discovery

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

SOCS proteins in regulation of receptor tyrosine kinase signaling

(2014) Julhash U. Kazi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17–92-Bim pathway in macrophages

(2014) Yihong Cai et al.   CELLULAR SIGNALLING

The regulation role of interferon regulatory factor-1 gene and clinical relevance

(2014) Lei Dou et al.   HUMAN IMMUNOLOGY

Immuno-miRs: critical regulators of T-cell development, function and ageing

(2014) Bart-Jan Kroesen et al.   IMMUNOLOGY

miR-19b promotes tumor growth and metastasis via targeting TP53

(2014) Y. Fan et al.   RNA

Targeting miR-21 to Treat Psoriasis

(2014) J. Guinea-Viniegra et al.   Science Translational Medicine

Oral lichen planus: Focus on etiopathogenesis

(2013) Márcia Rodrigues Payeras et al.   ARCHIVES OF ORAL BIOLOGY

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Regulation of the Hif-system by micro-RNA 17 and 20a – Role during monocyte-to-macrophage differentiation

(2013) David M. Poitz et al.   MOLECULAR IMMUNOLOGY

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interplay between microRNAs and the STAT3 signaling pathway in human cancers

(2013) Qing Cao et al.   PHYSIOLOGICAL GENOMICS

Tumor Necrosis Factor α-Induced MicroRNA-18a Activates Rheumatoid Arthritis Synovial Fibroblasts Through a Feedback Loop in NF-κB Signaling

(2012) Michelle Trenkmann et al.   ARTHRITIS AND RHEUMATISM

STAT1 expression and activation is increased in lesional psoriatic skin

(2012) A. Hald et al.   BRITISH JOURNAL OF DERMATOLOGY

MicroRNA-31 Is Overexpressed in Psoriasis and Modulates Inflammatory Cytokine and Chemokine Production in Keratinocytes via Targeting Serine/Threonine Kinase 40

(2012) N. Xu et al.   JOURNAL OF IMMUNOLOGY

Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

(2011) Mark Boguniewicz et al.   IMMUNOLOGICAL REVIEWS