CD47-ligation induced cell death in T-acute lymphoblastic leukemia

Cancer immunotherapy targeting the CD47/SIRPα axis

(2017) Kipp Weiskopf   EUROPEAN JOURNAL OF CANCER

Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies

(2017) E C Pietsch et al.   Blood Cancer Journal

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding

(2016) Penka S. Petrova et al.   CLINICAL CANCER RESEARCH

A review of new agents evaluated against pediatric acute lymphoblastic leukemia by the Pediatric Preclinical Testing Program

(2016) L Jones et al.   LEUKEMIA

Honokiol targets mitochondria to halt cancer progression and metastasis

(2016) Jing Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

α-Integrin expression and function modulates presentation of cell surface calreticulin

(2016) C-C Liu et al.   Cell Death & Disease

Pharmacogenetics predictive of response and toxicity in acute lymphoblastic leukemia therapy

(2015) Lin Mei et al.   BLOOD REVIEWS

Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms

(2015) M. Cioffi et al.   CLINICAL CANCER RESEARCH

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

(2015) Xiaojuan Liu et al.   NATURE MEDICINE

Treatment of Pediatric Acute Lymphoblastic Leukemia

(2015) Stacy L. Cooper et al.   PEDIATRIC CLINICS OF NORTH AMERICA

CD47 Agonist Peptides Induce Programmed Cell Death in Refractory Chronic Lymphocytic Leukemia B Cells via PLCγ1 Activation: Evidence from Mice and Humans

(2015) Ana-Carolina Martinez-Torres et al.   PLOS MEDICINE

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

(2015) Jie Liu et al.   PLoS One

CD47 does not mediate amyloid-β(1–42) protofibril-stimulated microglial cytokine release

(2014) Sanjib Karki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Honokiol Induces Cell Cycle Arrest and Apoptosis Via Inhibiting Class I Histone Deacetylases in Acute Myeloid Leukemia

(2014) Hai-Ying Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CD47-dependent immunomodulatory and angiogenic activities of extracellular vesicles produced by T cells

(2014) Sukhbir Kaur et al.   MATRIX BIOLOGY

CD47-Independent Effects Mediated by the TSP-Derived 4N1K Peptide

(2014) Pascal Leclair et al.   PLoS One

A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity

(2013) Valerie R. Wiersma et al.   BRITISH JOURNAL OF HAEMATOLOGY

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest

(2012) E Sick et al.   BRITISH JOURNAL OF PHARMACOLOGY

Honokiol: A Novel Natural Agent for Cancer Prevention and Therapy

(2012) S. Arora et al.   CURRENT MOLECULAR MEDICINE

The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications

(2012) Mark P Chao et al.   CURRENT OPINION IN IMMUNOLOGY

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new disulfide-linked dimer of a single-chain antibody fragment against human CD47 induces apoptosis in lymphoid malignant cells via the hypoxia inducible factor-1α pathway

(2011) Morihiko Sagawa et al.   CANCER SCIENCE

Heparan Sulfate Modification of the Transmembrane Receptor CD47 Is Necessary for Inhibition of T Cell Receptor Signaling by Thrombospondin-1

(2011) Sukhbir Kaur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Late Effects of Childhood Leukemia Therapy

(2011) Joy M. Fulbright et al.   Current Hematologic Malignancy Reports

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

(2009) Levi E. Fried et al.   ANTIOXIDANTS & REDOX SIGNALING

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton

(2009) S. Barbier et al.   HAEMATOLOGICA

Noxa: at the tip of the balance between life and death

(2009) C Ploner et al.   ONCOGENE

Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling

(2009) J. B. Maxhimer et al.   Science Translational Medicine

Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death

(2008) Dipanjan Chowdhury et al.   Annual Review of Immunology

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer

(2008) Hongyu Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY