CD47 Agonist Peptides Induce Programmed Cell Death in Refractory Chronic Lymphocytic Leukemia B Cells via PLCγ1 Activation: Evidence from Mice and Humans

Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1

(2014) Joanne L. Parker et al.   NATURE

Genetic and epigenetic basis of chronic lymphocytic leukemia

(2013) José I. Martín-Subero et al.   CURRENT OPINION IN HEMATOLOGY

Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia

(2013) John C. Byrd et al.   NEW ENGLAND JOURNAL OF MEDICINE

Engineered SIRP  Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies

(2013) K. Weiskopf et al.   SCIENCE

B cell receptor signaling in chronic lymphocytic leukemia

(2013) Jan A. Burger et al.   TRENDS IN IMMUNOLOGY

Blockade of CD47 increases survival of mice exposed to lethal total body irradiation

(2013) David R. Soto-Pantoja et al.   Scientific Reports

Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors

(2013) Sukhbir Kaur et al.   Scientific Reports

The degree of BCR and NFAT activation predicts clinical outcomes in chronic lymphocytic leukemia

(2012) C. Le Roy et al.   BLOOD

CD47 functions as a molecular switch for erythrocyte phagocytosis

(2012) P. Burger et al.   BLOOD

Thrombospondin-1-derived 4N1K peptide expression is negatively associated with malignant aggressiveness and prognosis in urothelial carcinoma of the upper urinary tract

(2012) Yasuyoshi Miyata et al.   BMC CANCER

Mitochondrial Ca2+ and apoptosis

(2012) Carlotta Giorgi et al.   CELL CALCIUM

The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications

(2012) Mark P Chao et al.   CURRENT OPINION IN IMMUNOLOGY

Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47

(2012) David R Soto-Pantoja et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Molecular pathogenesis of chronic lymphocytic leukemia

(2012) Gianluca Gaidano et al.   JOURNAL OF CLINICAL INVESTIGATION

The TRPM4 Channel Controls Monocyte and Macrophage, but Not Neutrophil, Function for Survival in Sepsis

(2012) N. Serafini et al.   JOURNAL OF IMMUNOLOGY

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

(2012) Wan Zhang et al.   NATURE CELL BIOLOGY

CD47Low Status on CD4 Effectors Is Necessary for the Contraction/Resolution of the Immune Response in Humans and Mice

(2012) Vu Quang Van et al.   PLoS One

On the mechanism of CD47 targeting in cancer

(2012) X. W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new disulfide-linked dimer of a single-chain antibody fragment against human CD47 induces apoptosis in lymphoid malignant cells via the hypoxia inducible factor-1α pathway

(2011) Morihiko Sagawa et al.   CANCER SCIENCE

CD47-signal regulatory protein-  (SIRP ) interactions form a barrier for antibody-mediated tumor cell destruction

(2011) X. W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional assessment of p53 in chronic lymphocytic leukemia

(2011) M Le Garff-Tavernier et al.   Blood Cancer Journal

Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

(2010) Patrick G. Hogan et al.   Annual Review of Immunology

Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma

(2010) Mark P. Chao et al.   CELL

Molecular basis of CLL

(2010) Yuri Pekarsky et al.   SEMINARS IN CANCER BIOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

A novel Rag2-/- c-/--xenograft model of human CLL

(2009) M. T. S. Bertilaccio et al.   BLOOD

How I treat CLL up front

(2009) J. G. Gribben   BLOOD

Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

(2009) Maike Buchner et al.   CANCER RESEARCH

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

Activation of CD47 receptors causes histamine secretion from mast cells

(2009) E. Sick et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton

(2009) S. Barbier et al.   HAEMATOLOGICA

Selective control of SIRP-α–positive airway dendritic cell trafficking through CD47 is critical for the development of TH2-mediated allergic inflammation

(2009) Marianne Raymond et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human thrombospondin’s (TSP-1) C-terminal domain opens to interact with the CD-47 receptor: A molecular modeling study

(2008) Nicolas Floquet et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

CD47 in the Immune Response: Role of Thrombospondin and SIRP-α Reverse Signaling

(2008) Marika Sarfati et al.   CURRENT DRUG TARGETS

Microenvironmental regulation of cancer development

(2008) Min Hu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Differential Interactions of Thrombospondin-1, -2, and -4 with CD47 and Effects on cGMP Signaling and Ischemic Injury Responses

(2008) Jeff S. Isenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic lymphocytic leukaemia

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Caspase-independent type III PCD: a new means to modulate cell death in chronic lymphocytic leukemia

(2008) H Merle-Béral et al.   LEUKEMIA

Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with CD47

(2008) Deborah Hatherley et al.   MOLECULAR CELL

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells

(2008) Gaëtan Barbet et al.   NATURE IMMUNOLOGY