Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
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Title
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
Authors
Keywords
-
Journal
mBio
Volume 9, Issue 2, Pages -
Publisher
American Society for Microbiology
Online
2018-03-05
DOI
10.1128/mbio.00221-18
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Note: Only part of the references are listed.- Middle East Respiratory Syndrome
- (2017) Yaseen M. Arabi et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2016) Erik De Clercq et al. CLINICAL MICROBIOLOGY REVIEWS
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- Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
- (2016) Travis K. Warren et al. NATURE
- Coronaviruses — drug discovery and therapeutic options
- (2016) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- SARS-like WIV1-CoV poised for human emergence
- (2016) Vineet D. Menachery et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease
- (2016) Raymond Taylor et al. Journal of Infection and Public Health
- Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease
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- L159F and V321A Sofosbuvir-Associated Hepatitis C Virus NS5B Substitutions
- (2015) Evguenia S. Svarovskaia et al. JOURNAL OF INFECTIOUS DISEASES
- A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
- (2015) Vineet D Menachery et al. NATURE MEDICINE
- Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
- (2015) Auda Eltahla et al. Viruses-Basel
- Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430
- (2014) Travis K. Warren et al. NATURE
- One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
- (2014) Lorenzo Subissi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
- (2014) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant
- (2014) S. Agnihothram et al. mBio
- Mechanism of Action of T-705 Ribosyl Triphosphate against Influenza Virus RNA Polymerase
- (2013) Hidehiro Sangawa et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Clinical management and infection control of SARS: Lessons learned
- (2013) Vincent C.C. Cheng et al. ANTIVIRAL RESEARCH
- SARS-CoV ORF1b-encoded nonstructural proteins 12–16: Replicative enzymes as antiviral targets
- (2013) Lorenzo Subissi et al. ANTIVIRAL RESEARCH
- Release of Severe Acute Respiratory Syndrome Coronavirus Nuclear Import Block Enhances Host Transcription in Human Lung Cells
- (2013) A. C. Sims et al. JOURNAL OF VIROLOGY
- T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro
- (2013) T. Baranovich et al. JOURNAL OF VIROLOGY
- Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
- (2013) T. Scobey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury
- (2013) L. E. Gralinski et al. mBio
- Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics
- (2013) Everett Clinton Smith et al. PLoS Pathogens
- Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides
- (2012) Aesop Cho et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- A time-of–drug addition approach to target identification of antiviral compounds
- (2011) Dirk Daelemans et al. Nature Protocols
- Arbovirus high fidelity variant loses fitness in mosquitoes and mice
- (2011) L. L. Coffey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing
- (2010) Lance D. Eckerle et al. PLoS Pathogens
- In Vivo Fitness Cost of the M184V Mutation in Multidrug-Resistant Human Immunodeficiency Virus Type 1 in the Absence of Lamivudine
- (2008) R. Paredes et al. JOURNAL OF VIROLOGY
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