Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus

(2016) Laura K. McMullan et al.   ANTIVIRAL RESEARCH

Sequelae of Ebola Virus Disease, Kenema District, Sierra Leone

(2015) Margaret Nanyonga et al.   CLINICAL INFECTIOUS DISEASES

Respiratory Syncytial Virus Inhibitor AZ-27 Differentially Inhibits Different Polymerase Activities at the Promoter

(2015) Sarah L. Noton et al.   JOURNAL OF VIROLOGY

Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study

(2015) Luke Hunt et al.   LANCET INFECTIOUS DISEASES

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

(2015) Emily P. Thi et al.   NATURE

Molecular Evidence of Sexual Transmission of Ebola Virus

(2015) Suzanne E. Mate et al.   NEW ENGLAND JOURNAL OF MEDICINE

Persistence of Ebola Virus in Ocular Fluid during Convalescence

(2015) Jay B. Varkey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications

(2015) Rodrigo Jácome et al.   PLoS One

Ebola drug trials lurch ahead

(2015) K. Kupferschmidt et al.   SCIENCE

Characterization of Clinical and Immunological Parameters During Ebola Virus Infection of Rhesus Macaques

(2015) Karen Martins et al.   VIRAL IMMUNOLOGY

Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail

(2015) Jeffrey R. Kugelman et al.   Cell Reports

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

(2014) Lisa Oestereich et al.   ANTIVIRAL RESEARCH

High-throughput, luciferase-based reverse genetics systems for identifying inhibitors of Marburg and Ebola viruses

(2014) Luke S. Uebelhoer et al.   ANTIVIRAL RESEARCH

Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model

(2014) Sophie J. Smither et al.   ANTIVIRAL RESEARCH

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430

(2014) Travis K. Warren et al.   NATURE

Euthanasia Assessment in Ebola Virus Infected Nonhuman Primates

(2014) Travis Warren et al.   Viruses-Basel

Respiratory Syncytial Virus Polymerase Can Initiate Transcription from Position 3 of the Leader Promoter

(2013) C. Z. Tremaglio et al.   JOURNAL OF VIROLOGY

Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides

(2012) Aesop Cho et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Species Difference of Esterase Expression and Hydrolase Activity in Plasma

(2012) Fatma Goksin Bahar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Ebola Virus Genome Plasticity as a Marker of Its Passaging History: A Comparison of In Vitro Passaging to Non-Human Primate Infection

(2012) Jeffrey R. Kugelman et al.   PLoS One

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

(2012) G. G. Olinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Respiratory Syncytial Virus Polymerase Has Multiple RNA Synthesis Activities at the Promoter

(2012) Sarah L. Noton et al.   PLoS Pathogens

Identification of Multiple Rate-limiting Steps during the Human Mitochondrial Transcription Cyclein Vitro

(2010) Maria F. Lodeiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleotide Analogue Prodrug Tenofovir Disoproxil Enhances Lymphoid Cell Loading following Oral Administration in Monkeys

(2009) Lucie Durand-Gasselin et al.   MOLECULAR PHARMACEUTICS