A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling

(2014) K. L. Matthews et al.   JOURNAL OF GENERAL VIROLOGY

Attenuation and Restoration of Severe Acute Respiratory Syndrome Coronavirus Mutant Lacking 2'-O-Methyltransferase Activity

(2014) V. D. Menachery et al.   JOURNAL OF VIROLOGY

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

(2013) Nianshuang Wang et al.   CELL RESEARCH

Coronaviruses in bats from Mexico

(2013) S. J. Anthony et al.   JOURNAL OF GENERAL VIROLOGY

Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests

(2013) Kwok-Hung Chan et al.   JOURNAL OF INFECTION

Evaluation of Serologic and Antigenic Relationships Between Middle Eastern Respiratory Syndrome Coronavirus and Other Coronaviruses to Develop Vaccine Platforms for the Rapid Response to Emerging Coronaviruses

(2013) Sudhakar Agnihothram et al.   JOURNAL OF INFECTIOUS DISEASES

Chimeric Exchange of Coronavirus nsp5 Proteases (3CLpro) Identifies Common and Divergent Regulatory Determinants of Protease Activity

(2013) Christopher C. Stobart et al.   JOURNAL OF VIROLOGY

Genetic Characterization of Betacoronavirus Lineage C Viruses in Bats Reveals Marked Sequence Divergence in the Spike Protein of Pipistrellus Bat Coronavirus HKU5 in Japanese Pipistrelle: Implications for the Origin of the Novel Middle East Respiratory Syndrome Coronavirus

(2013) S. K. P. Lau et al.   JOURNAL OF VIROLOGY

Release of Severe Acute Respiratory Syndrome Coronavirus Nuclear Import Block Enhances Host Transcription in Human Lung Cells

(2013) A. C. Sims et al.   JOURNAL OF VIROLOGY

The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies

(2013) S. Gierer et al.   JOURNAL OF VIROLOGY

Assessing Activity and Inhibition of Middle East Respiratory Syndrome Coronavirus Papain-Like and 3C-Like Proteases Using Luciferase-Based Biosensors

(2013) A. Kilianski et al.   JOURNAL OF VIROLOGY

Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study

(2013) Chantal BEM Reusken et al.   LANCET INFECTIOUS DISEASES

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

(2013) Xing-Yi Ge et al.   NATURE

Middle East Respiratory Syndrome Coronavirus Infections in Health Care Workers

(2013) Ziad A. Memish et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

(2013) T. Scobey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

(2013) P. R. Dormitzer et al.   Science Translational Medicine

Pathogenesis of Venezuelan equine encephalitis

(2013) Katherine G. Taylor et al.   VETERINARY MICROBIOLOGY

Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate

(2013) F. Almazan et al.   mBio

A Strategy To Estimate Unknown Viral Diversity in Mammals

(2013) S. J. Anthony et al.   mBio

Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus

(2013) L. Josset et al.   mBio

Phase I Safety and Immunogenicity Evaluations of an Alphavirus Replicon HIV-1 Subtype CgagVaccine in Healthy HIV-1-Uninfected Adults

(2012) M. Wecker et al.   Clinical and Vaccine Immunology

Evidence Supporting a Zoonotic Origin of Human Coronavirus Strain NL63

(2012) J. Huynh et al.   JOURNAL OF VIROLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

(2012) Chien-Te Tseng et al.   PLoS One

A phase I dose escalation trial of vaccine replicon particles (VRP) expressing prostate-specific membrane antigen (PSMA) in subjects with prostate cancer

(2012) Susan F. Slovin et al.   VACCINE

Genomic Characterization of a Newly Discovered Coronavirus Associated with Acute Respiratory Distress Syndrome in Humans

(2012) S. van Boheemen et al.   mBio

Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice

(2011) Jincun Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Determinants of Severe Acute Respiratory Syndrome Coronavirus Pathogenesis and Virulence in Young and Aged Mouse Models of Human Disease

(2011) M. Frieman et al.   JOURNAL OF VIROLOGY

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

(2011) M. Bolles et al.   JOURNAL OF VIROLOGY

Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV

(2011) Matthew Frieman et al.   PLoS One

SARS-CoV and emergent coronaviruses: viral determinants of interspecies transmission

(2011) Meagan Bolles et al.   Current Opinion in Virology

Successful Vaccination Strategies That Protect Aged Mice from Lethal Challenge from Influenza Virus and Heterologous Severe Acute Respiratory Syndrome Coronavirus

(2010) T. Sheahan et al.   JOURNAL OF VIROLOGY

Role of Mouse Hepatitis Virus (MHV) Receptor Murine CEACAM1 in the Resistance of Mice to MHV Infection: Studies of Mice with Chimeric mCEACAM1a and mCEACAM1b

(2010) A. Hirai et al.   JOURNAL OF VIROLOGY

Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures

(2010) K. Pyrc et al.   JOURNAL OF VIROLOGY

Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates

(2010) Saskia L. Smits et al.   PLoS Pathogens

Acute Lung Injury Review

(2009) Kenji Tsushima et al.   INTERNAL MEDICINE

Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission

(2009) R. L. Graham et al.   JOURNAL OF VIROLOGY

Synthetic viruses: a new opportunity to understand and prevent viral disease

(2009) Eckard Wimmer et al.   NATURE BIOTECHNOLOGY

Comparison of Histochemical Methods for Murine Eosinophil Detection in an RSV Vaccine-enhanced Inflammation Model

(2009) David K. Meyerholz et al.   TOXICOLOGIC PATHOLOGY

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

(2009) Craig W. Day et al.   VIROLOGY

Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors

(2008) Arun K. Ghosh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Systematic Assembly of a Full-Length Infectious Clone of Human Coronavirus NL63

(2008) E. F. Donaldson et al.   JOURNAL OF VIROLOGY

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

(2008) K. Ratia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

(2008) M. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA