T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

Favipiravir (T-705) inhibits in vitro norovirus replication

(2012) J. Rocha-Pereira et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

(2011) H.-H. Hoffmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

(2011) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection of hepatitis C virus resistant to ribavirin

(2011) Dino A Feigelstock et al.   Virology Journal

Lethal mutagenesis of viruses

(2011) Celia Perales et al.   Current Opinion in Virology

In Vitro System for Modeling Influenza A Virus Resistance under Drug Pressure

(2010) A. N. Brown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture

(2010) Michelle Mendenhall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Antiviral Activity of Favipiravir (T-705) against Drug-Resistant Influenza and 2009 A(H1N1) Viruses

(2010) K. Sleeman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Drugs in Development for Influenza

(2010) David A. Boltz et al.   DRUGS

Structures of influenza A proteins and insights into antiviral drug targets

(2010) Kalyan Das et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biochemical Characterization of Enzyme Fidelity of Influenza A Virus RNA Polymerase Complex

(2010) Shilpa Aggarwal et al.   PLoS One

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

(2010) C.-Y. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds

(2010) Laura I. Levi et al.   PLoS Pathogens

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

(2009) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Intracellular metabolism of favipiravir (T-705) in uninfected and influenza A (H5N1) virus-infected cells

(2009) D. F. Smee et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis

(2009) V. Martin et al.   JOURNAL OF GENERAL VIROLOGY

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

T-705 (favipiravir) activity against lethal H5N1 influenza A viruses

(2009) M. Kiso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defective interfering viruses and their potential as antiviral agents

(2009) A. C. Marriott et al.   REVIEWS IN MEDICAL VIROLOGY

Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106

(2008) J. G. Julander et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity

(2008) H HOFFMANN et al.   ANTIVIRAL RESEARCH