Synthesis of biologically active boron-containing compounds

Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate

(2017) Yong-Kang Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and characterization of peptidyl boronate analogues as effective antimicrobial agents

(2017) D. V. R. Venugopal et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Chalcone–benzoxaborole hybrids as novel anticancer agents

(2016) Jiong Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Characterisation, and Antifungal Activities of Novel Benzodiazaborines

(2015) Jiyoung Yang et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Boron-Based Drug Design

(2015) Hyun Seung Ban et al.   CHEMICAL RECORD

Recent Developments in the Chemistry and Biological Applications of Benzoxaboroles

(2015) Agnieszka Adamczyk-Woźniak et al.   CHEMICAL REVIEWS

Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

(2015) Yong-Kang Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Investigational Agents for the Treatment of Gram-Negative Bacterial Infections: A Reality Check

(2015) Karen Bush   ACS Infectious Diseases

The unique chemistry of benzoxaboroles: Current and emerging applications in biotechnology and therapeutic treatments

(2014) C. Tony Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, Characterization, and Antibacterial Activity of Structurally Complex 2-Acylated 2,3,1-Benzodiazaborines and Related Compounds

(2014) Divya Kanichar et al.   CHEMISTRY & BIODIVERSITY

Tavaborole: First Global Approval

(2014) Anthony Markham   DRUGS

Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy

(2014) Marvin A Soriano-Ursúa et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Synthesis and Pharmacology of Proteasome Inhibitors

(2013) Andreas Rentsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure–activity relationships of 6-(aminomethylphenoxy)-benzoxaborole derivatives as anti-inflammatory agent

(2013) Tsutomu Akama et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and study of antibacterial activities of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles

(2013) SS Printsevskaya et al.   Future Medicinal Chemistry

Boron chemicals in diagnosis and therapeutics

(2013) Bhaskar C Das et al.   Future Medicinal Chemistry

Structural Optimization, Biological Evaluation, and Application of Peptidomimetic Prostate Specific Antigen Inhibitors

(2013) Maya B. Kostova et al.   JOURNAL OF MEDICINAL CHEMISTRY

Syntheses and anti-tubercular activity ofβ-substituted andα,β-disubstituted peptidylβ-aminoboronates and boronic acids

(2013) Alexey S. Gorovoy et al.   JOURNAL OF PEPTIDE SCIENCE

The synthesis of benzoxaboroles and their applications in medicinal chemistry

(2013) Jiong Zhang et al.   Science China-Chemistry

Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase

(2013) Qing-Hua Hu et al.   Scientific Reports

Boron-Containing Compounds as Preventive and Chemotherapeutic Agents for Cancer

(2012) Romulus I. Scorei et al.   Anti-Cancer Agents in Medicinal Chemistry

Boron-Containing Peptidomimetics - A Novel Class of Selective Anti-tubercular Drugs

(2012) Alexey S. Gorovoy et al.   Chemical Biology & Drug Design

Boron Containing Compounds as Protease Inhibitors

(2012) Reem Smoum et al.   CHEMICAL REVIEWS

Boron as a platform for new drug design

(2012) Laura Ciani et al.   Expert Opinion on Drug Discovery

Benzoxaborole antimalarial agents. Part 3: design and syntheses of (carboxy-13C-3,3-2H2)-labeled and (3-14C)-labeled 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

(2012) Yong-Kang Zhang et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Chalcone–Benzoxaborole Hybrid Molecules as Potent Antitrypanosomal Agents

(2012) Zhitao Qiao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties

(2011) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors

(2011) Yi Xia et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

(2011) Yong-Kang Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Alkoxyamine-cyanoborane adducts: efficient cyanoborane transfer agents

(2011) José M. Márquez et al.   CHEMICAL COMMUNICATIONS

Boron-containing inhibitors of synthetases

(2011) Stephen J. Baker et al.   CHEMICAL SOCIETY REVIEWS

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

(2011) Robert T. Jacobs et al.   PLoS Neglected Tropical Diseases

Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates

(2010) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease

(2010) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease

(2010) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease

(2010) Charles Z. Ding et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents

(2010) Yong-Kang Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, in Vitro and in Vivo Biological Evaluation, and Comprehensive Understanding of Structure−Activity Relationships of Dipeptidyl Boronic Acid Proteasome Inhibitors Constructed from β-Amino Acids

(2010) Yongqiang Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase Inhibitors

(2010) Oliv Eidam et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of dipeptidyl peptidase-4 inhibitors: a brief overview

(2010) Naveen Mulakayala et al.   TETRAHEDRON

Diverse reactivity of 2-formylphenylboronic acid with secondary amines: synthesis of 3-amino-substituted benzoxaboroles

(2010) Agnieszka Adamczyk-Woźniak et al.   TETRAHEDRON LETTERS

Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents

(2010) Dazhong Ding et al.   ACS Medicinal Chemistry Letters

Synthesis and antiviral activity of HCV NS3/4A peptidomimetic boronic acid inhibitors

(2009) Amogh Boloor et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Benzoxaboroles – Old compounds with new applications

(2009) Agnieszka Adamczyk-Woźniak et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Convenient and versatile synthesis of formyl-substituted benzoxaboroles

(2009) Long Ye et al.   TETRAHEDRON

Synthesis, Characterization, and Antifungal Activity of Boron-Containing Thiosemicarbazones

(2008) Justin W. Hicks et al.   CHEMISTRY & BIODIVERSITY