Boron chemicals in diagnosis and therapeutics

Effects of bortezomib in sensitizing human prostate cancer cell lines to NK-mediated cytotoxicity

(2012) Wei Hu et al.   ASIAN JOURNAL OF ANDROLOGY

Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C

(2012) Astrid Zervosen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Development of Boronic Acids as Sensors and Separation Tools

(2012) John S. Fossey et al.   CHEMICAL RECORD

Boron Containing Compounds as Protease Inhibitors

(2012) Reem Smoum et al.   CHEMICAL REVIEWS

Disclosing the Structure/Activity Correlation in Trivalent Boron-Containing Compounds: A Tendency Map

(2012) Jessica Cid et al.   CHEMISTRY-A EUROPEAN JOURNAL

ROS-Inducible DNA Cross-Linking Agent as a New Anticancer Prodrug Building Block

(2012) Sheng Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis, chemical and enzymatic hydrolysis, and aqueous solubility of amino acid ester prodrugs of 3-carboranyl thymidine analogs for boron neutron capture therapy of brain tumors

(2012) Sherifa Hasabelnaby et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Boron as a platform for new drug design

(2012) Laura Ciani et al.   Expert Opinion on Drug Discovery

New therapeutic options for onychomycosis

(2012) Aditya K Gupta et al.   EXPERT OPINION ON PHARMACOTHERAPY

Dietary boron: Progress in establishing essential roles in human physiology

(2012) Curtiss D. Hunt   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer

(2012) Rolf F Barth et al.   Radiation Oncology

Design and synthesis of boron containing potential pan-RAR inverse agonists

(2012) Bhaskar C. Das et al.   TETRAHEDRON LETTERS

Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs

(2012) Bhaskar C. Das et al.   TETRAHEDRON LETTERS

Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer

(2012) Quan Jiang et al.   ACS Medicinal Chemistry Letters

Boronated unnatural cyclic amino acids as potential delivery agents for neutron capture therapy

(2011) George W. Kabalka et al.   APPLIED RADIATION AND ISOTOPES

Boron neutron capture in prostate cancer cells

(2011) Linda Yasui et al.   APPLIED RADIATION AND ISOTOPES

Molecular targets of oxidative stress

(2011) Simon V. Avery   BIOCHEMICAL JOURNAL

Target identification of bioactive compounds

(2011) Etsu Tashiro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

BODIPY-modified 2′-deoxyguanosine as a novel tool to detect DNA damages

(2011) Takeji Takamura-Enya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The formulation of polyhedral boranes for the boron neutron capture therapy of cancer

(2011) Gianpiero Calabrese et al.   DRUG DISCOVERY TODAY

Reactive oxygen species in cardiovascular disease

(2011) Koichi Sugamura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Topological Principles of Borosilicate Glass Chemistry

(2011) Morten M. Smedskjaer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Hydrogen Peroxide Inducible DNA Cross-Linking Agents: Targeted Anticancer Prodrugs

(2011) Yunyan Kuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease

(2011) Yifei Zhong et al.   PLoS One

Design and synthesis of 3,5-disubstituted 1,2,4-oxadiazole containing retinoids from a retinoic acid receptor agonist

(2011) Bhaskar C. Das et al.   TETRAHEDRON LETTERS

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

(2011) Robert T. Jacobs et al.   PLoS Neglected Tropical Diseases

Boron Nitride Nanotubes and Nanosheets

(2010) Dmitri Golberg et al.   ACS Nano

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates

(2010) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease

(2010) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease

(2010) Xianfeng Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1α inhibitors

(2010) Kazuki Shimizu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel Matrix Metalloproteinase Inhibitor [18F]Marimastat-Aryltrifluoroborate as a Probe for In vivo Positron Emission Tomography Imaging in Cancer

(2010) U. auf dem Keller et al.   CANCER RESEARCH

Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer

(2010) E. Kupperman et al.   CANCER RESEARCH

Assembling Ligands In Situ Using Bioorthogonal Boronate Ester Synthesis

(2010) Sung Bin Y. Shin et al.   CHEMISTRY & BIOLOGY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Proteasome Inhibitors: Recent Advances and New Perspectives In Medicinal Chemistry

(2010) E. Genin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

(2010) Lawrence R. Dick et al.   DRUG DISCOVERY TODAY

Current Challenges in Antimicrobial Chemotherapy

(2010) Carine Bebrone et al.   DRUGS

Potential applications of boron nitride nanotubes as drug delivery systems

(2010) Gianni Ciofani   Expert Opinion on Drug Delivery

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib

(2010) Ioannis A. Voutsadakis et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Regulation of Lung Cancer Cell Migration and Invasion by Reactive Oxygen Species and Caveolin-1

(2010) Sudjit Luanpitpong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Convection enhanced delivery of carboranylporphyrins for neutron capture therapy of brain tumors

(2010) Shinji Kawabata et al.   JOURNAL OF NEURO-ONCOLOGY

A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells

(2010) Bryan C. Dickinson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Forward Chemical Screen in Zebrafish Identifies a Retinoic Acid Derivative with Receptor Specificity

(2010) Bhaskar C. Das et al.   PLoS One

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

(2010) G. C. Van de Bittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

(2010) H. M. H. G. Albers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Toxicological Investigation and Antinociceptive Property of Potassium Thiophene-3-Trifluoroborate

(2009) Roberta A. Oliveira et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

A novel carborane analog, BE360, with a carbon-containing polyhedral boron-cluster is a new selective estrogen receptor modulator for bone

(2009) Michiko Hirata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Design, synthesis and biological evaluation of tripeptide boronic acid proteasome inhibitors

(2009) Yongqiang Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of boronic acid derivatives of tyropeptin: Proteasome inhibitors

(2009) Takumi Watanabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Reversibility of symptomatic peripheral neuropathy with bortezomib in the phase III APEX trial in relapsed multiple myeloma: impact of a dose-modification guideline

(2009) Paul G. Richardson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Phase II Trial of Talabostat and Docetaxel in Advanced Non-small Cell Lung Cancer

(2009) R.M. Eager et al.   CLINICAL ONCOLOGY

Therapeutic potential of boron-containing compounds

(2009) Stephen J Baker et al.   Future Medicinal Chemistry

Design, Synthesis, and Biological Activity of Boronic Acid-Based Histone Deacetylase Inhibitors

(2009) Nobuaki Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Evaluation of 3-(Dihydroxyboryl)benzoic Acids asd,d-Carboxypeptidase R39 Inhibitors

(2009) Steven R. Inglis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight

(2009) Ian M. Fearon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles

(2009) Elena Seiradake et al.   JOURNAL OF MOLECULAR BIOLOGY

Fluorescent BODIPY-Based Zn(II) Complex as a Molecular Probe for Selective Detection of Neurofibrillary Tangles in the Brains of Alzheimer’s Disease Patients

(2009) Akio Ojida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Boron Nitride Nanotubes Are Noncytotoxic and Can Be Functionalized for Interaction with Proteins and Cells

(2009) Xing Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A phase I/II study of bortezomib and capecitabine in patients with metastatic breast cancer previously treated with taxanes and/or anthracyclines

(2008) P. Schmid et al.   ANNALS OF ONCOLOGY

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

(2008) S. D. Seiwert et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase Inhibitors

(2008) Kavya Ramkumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potent inhibitors of HCV-NS3 protease derived from boronic acids

(2008) Srikanth Venkatraman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Characterization, and Antifungal Activity of Boron-Containing Thiosemicarbazones

(2008) Justin W. Hicks et al.   CHEMISTRY & BIODIVERSITY

Potent and Selective Peptidyl Boronic Acid Inhibitors of the Serine Protease Prostate-Specific Antigen

(2008) Aaron M. LeBeau et al.   CHEMISTRY & BIOLOGY

Discovery of Aryltrifluoroborates as Potent Sodium/Iodide Symporter (NIS) Inhibitors

(2008) Nathalie Lecat-Guillet et al.   ChemMedChem

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

(2008) R. Z. Orlowski et al.   CLINICAL CANCER RESEARCH

The dipeptidyl peptidase-4 inhibitor PHX1149 improves blood glucose control in patients with type 2 diabetes mellitus

(2008) G. Garcia-Soria et al.   DIABETES OBESITY & METABOLISM

Toward [18F]-Labeled Aryltrifluoroborate Radiotracers: In Vivo Positron Emission Tomography Imaging of Stable Aryltrifluoroborate Clearance in Mice

(2008) Richard Ting et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Recognition of Protein Tetraserine Motifs with a Cell-Permeable, Pro-fluorescent Bis-boronic Acid

(2008) Tiffany L. Halo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folate Functionalized Boron Nitride Nanotubes and their Selective Uptake by Glioblastoma Multiforme Cells: Implications for their Use as Boron Carriers in Clinical Boron Neutron Capture Therapy

(2008) Gianni Ciofani et al.   Nanoscale Research Letters

Application of PET/CT in the Development of Novel Anticancer Drugs

(2008) D. S. Boss et al.   ONCOLOGIST

Structure-based optimization of cephalothin-analogue boronic acids as β-lactamase inhibitors

(2007) Stefania Morandi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Biologically active compounds of semi-metals

(2007) Tomáš Řezanka et al.   PHYTOCHEMISTRY